@article { , title = {PVC Does Not Influence Cadmium Uptake or Effects in the Mussel (Mytilus edulis)}, abstract = {Microplastics have become a global concern in recent years. In this study, we studied (i) whether the presence of polyvinyl chloride (PVC) microparticles may affect cadmium (Cd) uptake in mussel (Mytilus edulis); and (ii) the biological effects of PVC microparticles exposure alone or in combination with Cd. Significant Cd uptake in digestive gland was observed following Cd exposure. However, PVC did not significantly increase Cd uptake compared with Cd alone treatment. In terms of biological impacts, significantly lower neutral red retention (NRR) time and elevated expression of Metallothionein isoform 20-IV (MT-20) were observed in mussels exposed to Cd alone, or combined with microplastics, yet there was no significant difference between them. catalase (CAT) expression only showed a significant increase in mussels exposed to Cd alone. This work provides an insight into the relationship on resulting biological impacts between these two contaminants.}, doi = {10.1007/s00128-020-02789-x}, eissn = {1432-0800}, issn = {0007-4861}, issue = {3}, journal = {Bulletin of Environmental Contamination and Toxicology}, pages = {315-320}, publicationstatus = {Published}, publisher = {Springer (part of Springer Nature)}, url = {https://hull-repository.worktribe.com/output/3378414}, volume = {104}, keyword = {Specialist Research - Other, Toxicology, Pollution, Health, Toxicology and Mutagenesis, General Medicine, PVC microplastics, Cd, Mussel, Toxicity}, year = {2020}, author = {Li, Jiana and Chapman, Emma C. and Shi, Huahong and Rotchell, Jeanette M.} }