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Antitumor and Protective Effects of Melatonin: The Potential Roles of MicroRNAs (2022)
Book Chapter
Ashrafizadeh, M., Ahmadi, Z., Yaribeygi, H., Sathyapalan, T., Jamialahmadi, T., & Sahebkar, A. (2022). Antitumor and Protective Effects of Melatonin: The Potential Roles of MicroRNAs. In A. Sahebkar, & T. Sathyapalan (Eds.), Natural Products and Human Diseases (463-471). Cham: Springer. https://doi.org/10.1007/978-3-030-73234-9_31

MicroRNAs (miRNAs) are endogenous short noncoding RNAs with approximately 22 nucleotides. The primary function of miRNAs is the negative regulation of target gene expression via mRNA degradation or translation inhibition. During recent years, much at... Read More about Antitumor and Protective Effects of Melatonin: The Potential Roles of MicroRNAs.

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase 2b Trial of P2X3 Receptor Antagonist Sivopixant for Refractory or Unexplained Chronic Cough (2022)
Journal Article
McGarvey, L., Smith, J. A., Morice, A., Birring, S. S., Chung, K. F., Dicpinigaitis, P. V., …Gomez, J. C. (2022). A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase 2b Trial of P2X3 Receptor Antagonist Sivopixant for Refractory or Unexplained Chronic Cough. Lung, https://doi.org/10.1007/s00408-022-00592-5

Introduction: To determine the optimal dose of sivopixant, a highly selective P2X3 receptor antagonist, for refractory or unexplained chronic cough (RCC/UCC). Methods: In this phase 2b, randomized, double-blind, placebo-controlled, parallel-group, mu... Read More about A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase 2b Trial of P2X3 Receptor Antagonist Sivopixant for Refractory or Unexplained Chronic Cough.

European respiratory society guidelines on the diagnosis and treatment of chronic cough in adults and children (2021)
Journal Article
Morice, A. H., Millqvist, E., Bieksiene, K., Birring, S. S., Dicpinigaitis, P., Ribas, C. D., …Zacharasiewicz, A. (2021). European respiratory society guidelines on the diagnosis and treatment of chronic cough in adults and children. Pulmonologiya, 31(4), 418-438. https://doi.org/10.18093/0869-0189-2021-31-4-418-438

These guidelines incorporate the recent advances in chronic cough pathophysiology, diagnosis and treatment. The concept of cough hypersensitivity has allowed an umbrella term that explains the exquisite sensitivity of patients to external stimuli suc... Read More about European respiratory society guidelines on the diagnosis and treatment of chronic cough in adults and children.

Preface (2021)
Book Chapter
Sahebkar, A., & Sathyapalan, T. (2021). Preface. In A. Sahebkar, & T. Sathyapalan (Eds.), Natural Products and Human Diseases : Pharmacology, Molecular Targets, and Therapeutic Benefits (v). Cham: Springer Verlag. https://doi.org/10.1007/978-3-030-73234-9

Impact of COVID-19 on vascular patients worldwide: analysis of the COVIDSurg data (2021)
Journal Article
Hitchman, L., & Machin, M. (2021). Impact of COVID-19 on vascular patients worldwide: analysis of the COVIDSurg data. Journal of Cardiovascular Surgery, 62(6), 558-70. https://doi.org/10.23736/S0021-9509.21.12024-5

BACKGROUND: The COVIDSurg collaborative was an international multicenter prospective analysis of perioperative data from 235 hospitals in 24 countries. it found that perioperative COVID-19 infection was associated with a mortality rate of 24%. at the... Read More about Impact of COVID-19 on vascular patients worldwide: analysis of the COVIDSurg data.

The use of perioperative prophylactic antibiotics following excision of ulcerated skin lesions in the UK – A national, multi-speciality survey of clinicians (2021)
Journal Article
Totty, J., Matin, R., Wernham, A., Ray, R., Thomas-Jones, E., & Abbott, R. (in press). The use of perioperative prophylactic antibiotics following excision of ulcerated skin lesions in the UK – A national, multi-speciality survey of clinicians. Clinical and experimental dermatology, https://doi.org/10.1111/ced.15075

Skin cancer is the most common malignancy in the UK, and up to a third of lesions are ulcerated at the time of excision. Ulceration has been shown to increase the risk of developing surgical site infection post-excision, with some studies finding inf... Read More about The use of perioperative prophylactic antibiotics following excision of ulcerated skin lesions in the UK – A national, multi-speciality survey of clinicians.

Impact of pharmacological interventions on anthropometric indices in women with polycystic ovary syndrome: a systematic review and meta‐analysis of randomised controlled trials (2021)
Journal Article
Abdalla, M. A., Shah, N., Deshmukh, H., Sahebkar, A., Östlundh, L., Al‐Rifai, R. H., …Sathyapalan, T. (in press). Impact of pharmacological interventions on anthropometric indices in women with polycystic ovary syndrome: a systematic review and meta‐analysis of randomised controlled trials. Clinical Endocrinology, https://doi.org/10.1111/cen.14663

Context: Polycystic ovary syndrome (PCOS) is a heterogeneous condition affecting women of reproductive age and is associated with increased body weight. Objective: To review the literature on the effect of different pharmacological interventions on t... Read More about Impact of pharmacological interventions on anthropometric indices in women with polycystic ovary syndrome: a systematic review and meta‐analysis of randomised controlled trials.

Genetic risk for the polycystic ovary syndrome, bone mineral density and fractures in women and men: A UK Biobank Mendelian randomisation study (2021)
Journal Article
Deshmukh, H., Shah, N., Papageorgiou, M., Abdalla, M. A., Lhaf, F., Aye, M., & Sathyapalan, T. (2022). Genetic risk for the polycystic ovary syndrome, bone mineral density and fractures in women and men: A UK Biobank Mendelian randomisation study. Bone, 155, Article 116285. https://doi.org/10.1016/j.bone.2021.116285

Introduction: There is conflicting data on the effect of polycystic ovary syndrome (PCOS) on bone mineral density (BMD) and fracture risk. Recent genetic data suggest that men may also carry genetic risk factors for PCOS; the associations of these fa... Read More about Genetic risk for the polycystic ovary syndrome, bone mineral density and fractures in women and men: A UK Biobank Mendelian randomisation study.