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Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study (2020)
Journal Article
Nichols, S., Taylor, C., Goodman, T., Page, R., Kallvikbacka-Bennett, A., Nation, F., …Ingle, L. (2020). Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study. International journal of cardiology, 305, 25-34. https://doi.org/10.1016/j.ijcard.2020.01.044

© 2020 The Authors Background: Recent evidence suggests that routine exercise-based cardiac rehabilitation (CR) may not lead to a substantial increase in estimated peak oxygen uptake (V̇O2peak). This could reduce the potential benefits of CR and expl... Read More about Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study.

Clinical and prognostic association of total atrial and conduction time in patients with heart failure: a report from Studies Investigating Co-morbidities Aggravating Heart Failure (2019)
Journal Article
Nuzzi, V., Pellicori, P., Nikolaidou, T., Kallvikbacka-Bennett, A., Torromeo, C., Barilla, F., …Clark, A. (2019). Clinical and prognostic association of total atrial and conduction time in patients with heart failure: a report from Studies Investigating Co-morbidities Aggravating Heart Failure. European journal of heart failure, 20(7), 442–449. https://doi.org/10.2459/JCM.0000000000000802

Background The total atrial conduction time can be measured as the time from the onset of the P wave on the ECG to the peak of the A wave recorded at the mitral annulus using tissue Doppler imaging (A′; P-A′TDI); when prolonged, it might predict inci... Read More about Clinical and prognostic association of total atrial and conduction time in patients with heart failure: a report from Studies Investigating Co-morbidities Aggravating Heart Failure.

Characteristics and outcome of acute heart failure patients according to the severity of peripheral oedema (2019)
Journal Article
Shoaib, A., Mamas, M. A., Ahmad, Q. S., McDonagh, T. M., Hardman, S. M., Rashid, M., …Cleland, J. G. F. (2019). Characteristics and outcome of acute heart failure patients according to the severity of peripheral oedema. International journal of cardiology, 285, 40-46. https://doi.org/10.1016/j.ijcard.2019.03.020

Background Most trials of patients hospitalized for heart failure focus on breathlessness (alveolar pulmonary oedema) but worsening peripheral oedema is also an important presentation. We investigated the relationship between the severity of periphe... Read More about Characteristics and outcome of acute heart failure patients according to the severity of peripheral oedema.

Prevalence, pattern and clinical relevance of ultrasound indices of congestion in outpatients with heart failure (2019)
Journal Article
Pellicori, P., Shah, P., Cuthbert, J., Urbinati, A., Zhang, J., Kallvikbacka-Bennett, A., …Cleland, J. G. F. (2019). Prevalence, pattern and clinical relevance of ultrasound indices of congestion in outpatients with heart failure. European journal of heart failure, 21(7), 904-916. https://doi.org/10.1002/ejhf.1383

Aims Even if treatment controls symptoms, patients with heart failure may still be congested. We aimed at assessing the prevalence and clinical relevance of congestion in outpatients with chronic heart failure. Conclusions Many patients with chr... Read More about Prevalence, pattern and clinical relevance of ultrasound indices of congestion in outpatients with heart failure.

Are there patients missing from community heart failure registers? An audit of clinical practice (2018)
Journal Article
Cuthbert, J. J., Gopal, J., Crundall-Goode, A., & Clark, A. L. (2019). Are there patients missing from community heart failure registers? An audit of clinical practice. European Journal of Preventive Cardiology, 26(3), 204748731881083. https://doi.org/10.1177/2047487318810839

Background General practitioners in the UK are financially incentivised, via the Quality Outcomes Framework, to maintain a record of all patients at their practice with heart failure and manage them appropriately. The prevalence of heart failure rec... Read More about Are there patients missing from community heart failure registers? An audit of clinical practice.

Mode of presentation and mortality amongst patients hospitalized with heart failure? A report from the First Euro Heart Failure Survey (2018)
Journal Article
Shoaib, A., Farag, M., Nolan, J., Rigby, A., Patwala, A., Rashid, M., …Cleland, J. G. (2019). Mode of presentation and mortality amongst patients hospitalized with heart failure? A report from the First Euro Heart Failure Survey. Clinical Research in Cardiology, 108(5), 510-519. https://doi.org/10.1007/s00392-018-1380-6

© 2018, The Author(s). Background: Heart failure is heterogeneous in aetiology, pathophysiology, and presentation. Despite this diversity, clinical trials of patients hospitalized for HF deal with this problem as a single entity, which may be one rea... Read More about Mode of presentation and mortality amongst patients hospitalized with heart failure? A report from the First Euro Heart Failure Survey.

Warm water immersion in patients with chronic heart failure: a pilot study: Shah immerse: HF (2018)
Journal Article
Shah, P., Pellicori, P., Kallvikbacka-Bennett, A., Zhang, J., Pan, D., & Clark, A. L. (2019). Warm water immersion in patients with chronic heart failure: a pilot study: Shah immerse: HF. Clinical Research in Cardiology, 108(5), 468–476. https://doi.org/10.1007/s00392-018-1376-2

Background Patients with chronic conditions, such as heart failure, swim regularly and most rehabilitation exercises are conducted in warm hydrotherapy pools. However, little is known about the acute effects of warm water immersion (WWI) on cardiac... Read More about Warm water immersion in patients with chronic heart failure: a pilot study: Shah immerse: HF.

Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation? (2017)
Journal Article
Nichols, S., Gleadall-Siddall, D. O., Antony, R., Clark, A. L., Cleland, J. G. F., Carroll, S., & Ingle, L. (2018). Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation?. Clinical physiology and functional imaging, 38(4), 681-688. https://doi.org/10.1111/cpf.12468

Summary Objective Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method of determining VO2peak. When CPET is unavailable, VO2peak may be estimated from treadmill or cycle ergometer workloads and expressed as estimated metabolic equiva... Read More about Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation?.

Influence of case definition on incidence and outcome of acute coronary syndromes (2016)
Journal Article
Torabi, A., Cleland, J. G. F., Sherwi, N., Atkin, P., Panahi, H., Kilpatrick, E., …Rigby, A. (2016). Influence of case definition on incidence and outcome of acute coronary syndromes. Open heart, 3(2), e000487. https://doi.org/10.1136/openhrt-2016-000487

© 2016, BMJ Publishing Group. All rights reserved. Objective: Acute coronary syndromes (ACS) are common, but their incidence and outcome might depend greatly on how data are collected. We compared case ascertainment rates for ACS and myocardial infar... Read More about Influence of case definition on incidence and outcome of acute coronary syndromes.

Microvascular dysfunction in the immediate aftermath of chronic total coronary occlusion recanalization (2016)
Journal Article
Ladwiniec, A., Cunnington, M. S., Rossington, J., Thackray, S., Alamgir, F., & Hoye, A. (2016). Microvascular dysfunction in the immediate aftermath of chronic total coronary occlusion recanalization. Catheterization and Cardiovascular Interventions, 87(6), 1071-1079 . https://doi.org/10.1002/ccd.26392

Objectives The aim of this study was to compare microvascular resistance under both baseline and hyperemic conditions immediately after percutaneous coronary intervention (PCI) of a chronic total occlusion (CTO) with an unobstructed reference vessel... Read More about Microvascular dysfunction in the immediate aftermath of chronic total coronary occlusion recanalization.