Skip to main content

Prevalence of hepatitis B virus infection among blood donors at the Tamale Teaching Hospital, Ghana (2009)

Dongdem, Julius Tieroyaare; Kampo, Sylvanus; Soyiri, Ireneous N.; Asebga, Patrick Nsobila; Ziem, Juventus B.; Sagoe, Kenneth

Authors

Julius Tieroyaare Dongdem

Sylvanus Kampo

Patrick Nsobila Asebga

Juventus B. Ziem

Kenneth Sagoe



Abstract

Background: Despite education and availability of drugs and vaccines, hepatitis B virus (HBV) is still the most common severe liver infection in the world accounting for >1 million annual deaths worldwide. Transfusion of infected blood, unprotected sex and mother to child transmission are 3 key transmission routes of HBV in Ghana. There is high incidence of blood demanding health situations in northern Ghana resulting from anemia, accidents, malnutrition, etc. The higher the demand, the higher the possibility of transmitting HBV through infected blood. The aim of the investigation was to estimate the prevalence of HBV in blood donors which will provide justification for interventions that will help minimize or eliminate HBV infection in Ghana. Findings. We investigated the prevalence of HBV infection among blood donors at Tamale Teaching Hospital. The Wondfo HBsAg test kit was used to determine the concentration of HBsAg in 6,462 (576 voluntary and 5,878 replacement) donors as being 1 ng/ml. 10.79% of voluntary donors and 11.59% of replacement donors were HBsAg+. The 20-29 year group of voluntary donors was >2 times more likely to be HBsAg + than 40-60. Also the 20-29 year category of replacement donors was >4 times as likely to be HBsAg + than 50-69. Conclusions: Risk of infection was age, sex and donor type dependent. The 20-29 year category had the highest prevalence of HBsAg + cases, mostly males residing within the metropolis. © 2012 Dongdem et al; licensee BioMed Central Ltd.

Journal Article Type Article
Publication Date 2012
Journal BMC Research Notes
Print ISSN 1756-0500
Electronic ISSN 1756-0500
Publisher Springer Verlag
Peer Reviewed Peer Reviewed
Volume 5
Article Number 115
APA6 Citation Dongdem, J. T., Kampo, S., Soyiri, I. N., Asebga, P. N., Ziem, J. B., & Sagoe, K. (2012). Prevalence of hepatitis B virus infection among blood donors at the Tamale Teaching Hospital, Ghana (2009). BMC research notes, 5, https://doi.org/10.1186/1756-0500-5-115
DOI https://doi.org/10.1186/1756-0500-5-115
Keywords Blood donor; Adefovir; Voluntary donor; HBsAg level; Voluntary blood donor
Publisher URL https://bmcresnotes.biomedcentral.com/articles/10.1186/1756-0500-5-115
Additional Information © 2012 Dongdem et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative
Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is properly cited.

Files

Article (325 Kb)
PDF

Copyright Statement
© 2012 Dongdem et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative
Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is properly cited.





You might also like



Downloadable Citations

;