The role of high resolution oesophageal manometry in occult respiratory symptoms

Burke, Jennifer M.; Jackson, Warren; Morice, Alyn H.

Abstract

Purpose: Cough Hypersensitivity Syndrome is the urge to cough following minimal stimulation, but its mechanism and method of provocation remain unexplained. 121 patients (44 males, 77 females; age range 18–81 years) were evaluated. Procedures: High resolution manometry was performed on consecutive patients presenting with unexplained respiratory symptoms (Respiratory Group 61). Data were compared with matched controls, i.e. dyspepsia without respiratory symptoms (Dyspepsia Group 60). Main findings: Results showed increased inspiratory gastro-oesophageal pressure gradient due to significantly lower intra-oesophageal pressure on inspiration (p = 0.001), and reduced oesophageal motility in the Respiratory Group. Conclusions: Further research in respiratory conditions characterised by decreased intrathoracic pressure during inspiration is needed.

Citation

Burke, J. M., Jackson, W., & Morice, A. H. (2018). The role of high resolution oesophageal manometry in occult respiratory symptoms. Respiratory medicine, 138, 47-49. https://doi.org/10.1016/j.rmed.2018.03.027

• Journal Article Type: Article
• Acceptance Date: Mar 24, 2018
• Online Publication Date: Mar 27, 2018
• Publication Date: 2018-05
• Deposit Date: May 10, 2022
• Journal: Respiratory Medicine
• Print ISSN: 0954-6111
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 138
• Pages: 47-49
• DOI: https://doi.org/10.1016/j.rmed.2018.03.027
• Keywords: Cough; Manometry; Respiratory hypersensitivity
• Public URL: https://hull-repository.worktribe.com/output/816949