MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes
(2014)
Journal Article
Ardestani, A., Paroni, F., Azizi, Z., Kaur, S., Khobragade, V., Yuan, T., Frogne, T., Tao, W., Oberholzer, J., Pattou, F., Kerr Conte, J., & Maedler, K. (2014). MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes. Nature Medicine, 20(4), 385-397. https://doi.org/10.1038/nm.3482
Apoptotic cell death is a hallmark of the loss of insulin-producing beta cells in all forms of diabetes mellitus. Current treatments fail to halt the decline in functional beta cell mass, and strategies to prevent beta cell apoptosis and dysfunction... Read More about MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes.