Murine Creld1 controls cardiac development through activation of calcineurin/NFATc1 signaling

Mass, Elvira; Wachten, Dagmar; Aschenbrenner, Anna C.; Voelzmann, André; Hoch, Michael

doi:10.1016/j.devcel.2014.02.012

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Murine Creld1 controls cardiac development through activation of calcineurin/NFATc1 signaling (2014)
Journal Article
Mass, E., Wachten, D., Aschenbrenner, A. C., Voelzmann, A., & Hoch, M. (2014). Murine Creld1 controls cardiac development through activation of calcineurin/NFATc1 signaling. Developmental Cell, 28(6), 711-726. https://doi.org/10.1016/j.devcel.2014.02.012

Calcineurin is a heteromeric Ca<sup>2+</sup>-dependent serine/threonine phosphatase. It dephosphorylates the transcription factor nuclear factor of activated Tcells (NFAT) in the cytoplasm, which subsequently undergoes nuclear translocation. NFAT reg... Read More about Murine Creld1 controls cardiac development through activation of calcineurin/NFATc1 signaling.