All Outputs (2)

Western diet impairs metabolic remodelling and contractile efficiency in cardiac hypertrophy (2008)
Journal Article
Akki, A., & Seymour, A. L. (2009). Western diet impairs metabolic remodelling and contractile efficiency in cardiac hypertrophy. Cardiovascular research, 81(3), 610-617. https://doi.org/10.1093/cvr/cvn316

Metabolic remodelling in cardiac hypertrophy is underscored by a reduction in fatty acid (FA) oxidation. We tested whether this decline in FA oxidation in the presence of enhanced FA supply may predispose the hypertrophied myocardium to lipid accumul... Read More about Western diet impairs metabolic remodelling and contractile efficiency in cardiac hypertrophy.

Compensated cardiac hypertrophy is characterised by a decline in palmitate oxidation (2008)
Journal Article
Akki, A., Smith, K., & Seymour, A. M. L. (2008). Compensated cardiac hypertrophy is characterised by a decline in palmitate oxidation. Molecular and Cellular Biochemistry, 311(1-2), 215-224. https://doi.org/10.1007/s11010-008-9711-y

Cardiac hypertrophy is an independent risk factor in the development of heart failure. However, the cellular mechanisms underlying the transition from compensated hypertrophy to heart failure are incompletely understood. The aim of this study was to... Read More about Compensated cardiac hypertrophy is characterised by a decline in palmitate oxidation.