All Outputs (4)

Biological function and clinical implication of coagulation proteins during malignant transformation of pancreatic cells (2023)
Thesis
Haque, F. Biological function and clinical implication of coagulation proteins during malignant transformation of pancreatic cells. (Thesis). Hull York Medical School. https://hull-repository.worktribe.com/output/4371279

The premalignant pancreatic cellular genotype can remain stable for years before rapid malignant transformation, often associated with inflammation. Tissue factor (TF) is an inflammatory modulator regulated by factor VIIa (fVIIa) for its levels and a... Read More about Biological function and clinical implication of coagulation proteins during malignant transformation of pancreatic cells.

Investigation of the effects of anticoagulants on tissue factor mediated cellular processes (2021)
Thesis
Featherby, S. Investigation of the effects of anticoagulants on tissue factor mediated cellular processes. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4223521

Thrombotic complications are common in cancer patients and are amongst the leading causes of morbidity and mortality. Recently, it was reported that treatment of cancer patients with the low molecular weight heparin (LMWH) family of anticoagulants ca... Read More about Investigation of the effects of anticoagulants on tissue factor mediated cellular processes.

An investigation into the regulation of cellular homeostasis through modulation of cell-surface tissue factor (2020)
Thesis
Madkhali, Y. A. An investigation into the regulation of cellular homeostasis through modulation of cell-surface tissue factor. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4836545

In recent years it has become evident that cell-derived microvesicles (MV) influence the recipient cells through inducing signalling mechanisms which lead to cell proliferation or apoptosis. In addition, the excessive release of procoagulant MV durin... Read More about An investigation into the regulation of cellular homeostasis through modulation of cell-surface tissue factor.

Identification and functional characterization of putative mitochondrial iron transporters from the human pathogen Trypanosoma brucei (2017)
Thesis
Zheng, F. Identification and functional characterization of putative mitochondrial iron transporters from the human pathogen Trypanosoma brucei. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4221817

Trypanosoma brucei is a medically important protozoan parasite causing African sleeping sickness in humans. Treatment of this disease is possible, but is hindered by the limited availability of effective drugs as well as the rapid emergence of drug r... Read More about Identification and functional characterization of putative mitochondrial iron transporters from the human pathogen Trypanosoma brucei.