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Relationships between walking speed, T-score and age with gait parameters in older post-menopausal women with low bone mineral density (2018)
Journal Article
Dostanpor, A., Dobson, C. A., & Vanicek, N. (2018). Relationships between walking speed, T-score and age with gait parameters in older post-menopausal women with low bone mineral density. Gait and Posture, 64, (230-237). doi:10.1016/j.gaitpost.2018.05.005. ISSN 0966-6362

Background: The gait patterns of women with low bone mineral density (BMD) or osteoporosis have not been thoroughly explored, and when examined, often studied in relation to falls and kyphosis. Research question: The aim of this study was to investig... Read More

The potential role of variations in juvenile hip geometry on the development of Legg-Calvé-Perthes disease: a biomechanical investigation (2018)
Journal Article
Pinheiro, M. D. S., Dobson, C., Clarke, N. M., & Fagan, M. (2018). The potential role of variations in juvenile hip geometry on the development of Legg-Calvé-Perthes disease: a biomechanical investigation. Computer methods in biomechanics and biomedical engineering, 21(2), (194-200). doi:10.1080/10255842.2018.1437151. ISSN 1025-5842

© 2018 Informa UK Limited, trading as Taylor & Francis Group Legg-Calvé-Perthes disease (LCP) is one of the most poorly understood diseases in paediatric orthopaedics. One common trait of LCP is the marked morphological difference between healthy a... Read More

New insights into the biomechanics of Legg-Calvé-Perthes’ disease: The role of epiphyseal skeletal immaturity in vascular obstruction (2018)
Journal Article
Pinheiro, M., Dobson, C. A., Perry, D., & Fagan, M. J. (2018). New insights into the biomechanics of Legg-Calvé-Perthes’ disease: The role of epiphyseal skeletal immaturity in vascular obstruction. Bone & joint research, 7(2), (148-156). doi:10.1302/2046-3758.72.bjr-2017-0191.r1. ISSN 2046-3758

Objectives Legg–Calvé–Perthes’ disease (LCP) is an idiopathic osteonecrosis of the femoral head that is most common in children between four and eight years old. The factors that lead to the onset of LCP are still unclear; however, it is believed tha... Read More

The effect of boundary constraints on finite element modelling of the human pelvis (2017)
Journal Article
Watson, P., Dostanpor, A., Fagan, M. J., & Dobson, C. A. (2017). The effect of boundary constraints on finite element modelling of the human pelvis. Medical engineering & physics, 43, (48-57). doi:10.1016/j.medengphy.2017.02.001. ISSN 1350-4533

The use of finite element analysis (FEA) to investigate the biomechanics of anatomical systems critically relies on the specification of physiologically representative boundary conditions. The biomechanics of the pelvis has been the specific focus of... Read More

Tibial impacts and muscle activation during walking, jogging and running when performed overground, and on motorised and non-motorised treadmills (2016)
Journal Article
Montgomery, G., Abt, G., Dobson, C., Smith, T., & Ditroilo, M. (2016). Tibial impacts and muscle activation during walking, jogging and running when performed overground, and on motorised and non-motorised treadmills. Gait and Posture, 49, 120-126. doi:10.1016/j.gaitpost.2016.06.037

Purpose To examine tibial acceleration and muscle activation during overground (OG), motorised treadmill (MT) and non-motorised treadmill conditions (NMT) when walking, jogging and running at matched velocities. Methods An accelerometer recorded acce... Read More

Skeletal immaturity, rostral sparing, and disparate hip morphologies as biomechanical causes for Legg-Calvé-Perthes’ disease (2016)
Journal Article
Berthaume, M. A., Perry, D. C., Dobson, C. A., Witzel, U., Clarke, N. M., & Fagan, M. J. (2016). Skeletal immaturity, rostral sparing, and disparate hip morphologies as biomechanical causes for Legg-Calvé-Perthes’ disease. Clinical Anatomy, 29(6), (759-772). doi:10.1002/ca.22690. ISSN 0897-3806

Legg-Calvé-Perthes' (Perthes') disease is a developmental disease of the hip joint that may result in numerous short and long term problems. The etiology of the disease remains largely unknown, but the mechanism is believed to be vascular and/or biom... Read More

Sensitivity to model geometry in finite element analyses of reconstructed skeletal structures: Experience with a juvenile pelvis (2014)
Journal Article
Watson, P. J., Fagan, M. J., & Dobson, C. A. (2015). Sensitivity to model geometry in finite element analyses of reconstructed skeletal structures: Experience with a juvenile pelvis. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 229(1), 9-19. https://doi.org/10.1177/0954411914564476

Biomechanical analysis of juvenile pelvic growth can be used in the evaluation of medical devices and investigation of hip joint disorders. This requires access to scan data of healthy juveniles, which are not always freely available. This article an... Read More

Validation of a morphometric reconstruction technique applied to a juvenile pelvis (2010)
Journal Article
Watson, P., O'Higgins, P., Fagan, M. J., & Dobson, C. A. (2011). Validation of a morphometric reconstruction technique applied to a juvenile pelvis. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 225(1), 48-57. doi:10.1243/09544119jeim810

Three-dimensional reconstructions of bone geometry from microCT (computed tomography) data are frequently used in biomechanical and finite element analyses. Digitization of bone models is usually a simple process for specimens with a complete geometr... Read More

Masticatory loading and bone adaptation in the supraorbital torus of developing macaques (2008)
Journal Article
Fagan, M. J., Oxnard, C. E., Crompton, R. H., Dobson, C. A., Kupczik, K., O'Higgins, P., …Fagan, M. (2009). Masticatory loading and bone adaptation in the supraorbital torus of developing macaques. American journal of physical anthropology, 139(2), 193-203. doi:10.1002/ajpa.20972

Research on the evolution and adaptive significance of primate craniofacial morphologies has focused on adult, fully developed individuals. Here, we investigate the possible relationship between the local stress environment arising from masticatory l... Read More

Assessing mechanical function of the zygomatic region in macaques: validation and sensitivity testing of finite element models (2006)
Journal Article
Kupczik, K., Dobson, C. A., Fagan, M. J., Crompton, R. H., Oxnard, C. E., & O'Higgins, P. (2007). Assessing mechanical function of the zygomatic region in macaques: validation and sensitivity testing of finite element models. Journal of anatomy, 210(1), (41-53). doi:10.1111/j.1469-7580.2006.00662.x. ISSN 0021-8782

Crucial to the interpretation of the results of any finite element analysis of a skeletal system is a test of the validity of the results and an assessment of the sensitivity of the model parameters. We have therefore developed finite element models... Read More

Three dimensional stereolithography models of cancellous bone structures from μCT data: Testing and validation of finite element results (2006)
Journal Article
Dobson, C. A., Sisias, G., Phillips, R., Langton, C. M., & Fagan, M. J. (2006). Three dimensional stereolithography models of cancellous bone structures from μCT data: Testing and validation of finite element results. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 220(3), (481-484). doi:10.1243/09544119H00405. ISSN 0954-4119

Stereolithography (STL) models of complex cancellous bone structures have been produced from three-dimensional micro-computed tomography data sets of human cancellous bone histological samples from four skeletal sites. The STL models have been mechan... Read More

Stereo visualization of 3D trabecular bone structures produced by bone remodelling simulation (2003)
Journal Article
Sisias, G., Ward, J. W., Grunchec, J. A., Langton, C. M., Phillips, R., Dobson, C. A., …Fagan, M. J. (2003). Stereo visualization of 3D trabecular bone structures produced by bone remodelling simulation. Studies in health technology and informatics, 94, 258-264. doi:10.3233/978-1-60750-938-7-258

Adult human bone is constantly being renewed by a process known as remodelling. For cancellous bone this renewal process occurs at the interface between bone and marrow where bone is depleted by osteoclasts and rebuilt by osteoblasts. This remodellin... Read More

Algorithms for accurate rapid prototyping replication of cancellous bone voxel maps (2002)
Journal Article
Sisias, G., Langton, C., Phillips, R., Dobson, C., & Fagan, M. (2002). Algorithms for accurate rapid prototyping replication of cancellous bone voxel maps. Rapid Prototyping Journal, 8(1), (6-24). doi:10.1108/13552540210413266. ISSN 1355-2546

A set of algorithms has been developed and evaluated for 3D and 21/2D rapid prototyping replication of 3D reconstructions of cancellous bone samples. The algorithms replicate a voxel map without any loss of fidelity, so as to increase the validity of... Read More

Smoothing of pixelated finite element models of cancellous bone structures and the effect on the predicted structural properties of the bone (2002)
Journal Article
Sisias, G., Langton, C. M., Phillips, R., Dobson, C. A., & Fagan, M. J. (2002). Smoothing of pixelated finite element models of cancellous bone structures and the effect on the predicted structural properties of the bone. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 216(2), 145-149. doi:10.1243/0954411021536360

Many areas of biomedical engineering involve the modelling of biological systems, often using data from medical scanning techniques such as computed microtomography (μCT), and the prediction of the mechanical properties of these systems via finite el... Read More

Stochastically simulated assessment of anabolic treatment following varying degrees of cancellous bone resorption (2000)
Journal Article
Fagan, M., Dobson, C., Ganney, P., Haire, T., Langton, C., Sisias, G., …Fagan, M. (2000). Stochastically simulated assessment of anabolic treatment following varying degrees of cancellous bone resorption. Bone, 27(1), 111-118. doi:10.1016/s8756-3282(00)00290-8

The aim of this study was to investigate the recovery in cancellous bone stiffness resulting from anabolic treatment following varying degrees of resorption, using a stochastic simulation applied to a simplistic structure consisting of five vertical... Read More