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BiCyCLE NMES—neuromuscular electrical stimulation in the perioperative treatment of sarcopenia and myosteatosis in advanced rectal cancer patients: design and methodology of a phase II randomised controlled trial (2021)
Journal Article
Pring, E. T., Gould, L. E., Malietzis, G., Lung, P., Bharal, M., Fadodun, T., …Jenkins, J. T. (2021). BiCyCLE NMES—neuromuscular electrical stimulation in the perioperative treatment of sarcopenia and myosteatosis in advanced rectal cancer patients: design and methodology of a phase II randomised controlled trial. Trials, 22(1), Article 621. https://doi.org/10.1186/s13063-021-05573-2

Background: Colorectal cancer is associated with secondary sarcopenia (muscle loss) and myosteatosis (fatty infiltration of muscle) and patients who exhibit these host characteristics have poorer outcomes following surgery. Furthermore, patients, who... Read More about BiCyCLE NMES—neuromuscular electrical stimulation in the perioperative treatment of sarcopenia and myosteatosis in advanced rectal cancer patients: design and methodology of a phase II randomised controlled trial.

Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study (2020)
Journal Article
Nichols, S., Taylor, C., Goodman, T., Page, R., Kallvikbacka-Bennett, A., Nation, F., Clark, A. L., Birkett, S. T., Carroll, S., & Ingle, L. (2020). Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study. International journal of cardiology, 305, 25-34. https://doi.org/10.1016/j.ijcard.2020.01.044

© 2020 The Authors Background: Recent evidence suggests that routine exercise-based cardiac rehabilitation (CR) may not lead to a substantial increase in estimated peak oxygen uptake (V̇O2peak). This could reduce the potential benefits of CR and expl... Read More about Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study.

Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease - a CARE CR study (2018)
Journal Article
Nichols, S., O'Doherty, A. F., Taylor, C., Clark, A. L., Carroll, S., & Ingle, L. (2019). Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease - a CARE CR study. Clinical physiology and functional imaging, 39(1), 93-102. https://doi.org/10.1111/cpf.12539

BACKGROUND
In patients with chronic heart failure, there is a positive linear relationship between skeletal muscle mass (SMM) and peak oxygen consumption (V˙O2peak ); an independent predictor of all-cause mortality. We investigated the association b... Read More about Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease - a CARE CR study.

Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study (2018)
Journal Article
Nichols, S., Taylor, C., Page, R., Kallvikbacka-Bennett, A., Nation, F., Goodman, T., Clark, A. L., Carroll, S., & Ingle, L. (2018). Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study. Sports Medicine - Open, 4(1), https://doi.org/10.1186/s40798-018-0138-z

© 2018, The Author(s). Background: Higher cardiorespiratory fitness (CRF) is associated with lower morbidity and mortality in patients with coronary heart disease (CHD). The mechanisms for this are not fully understood. A more favourable cardiometabo... Read More about Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study.

Exercise dose and all-cause mortality within extended cardiac rehabilitation: a cohort study (2017)
Journal Article
Taylor, C., Tsakirides, C., Moxon, J., Moxon, J. W., Dudfield, M., Witte, K., Ingle, L., & Carroll, S. (2017). Exercise dose and all-cause mortality within extended cardiac rehabilitation: a cohort study. Open heart, 4(2), e000623. https://doi.org/10.1136/openhrt-2017-000623

Aims: To investigate the relationship between exercise participation, exercise ‘dose’ expressed as metabolic equivalent (MET) hours (h) per week, and prognosis in individuals attending an extended, community-based exercise rehabilitation programme. M... Read More about Exercise dose and all-cause mortality within extended cardiac rehabilitation: a cohort study.

Submaximal fitness and mortality risk reduction in coronary heart disease: A retrospective cohort study of community-based exercise rehabilitation (2016)
Journal Article
Taylor, C., Tsakirides, C., Moxon, J., Moxon, J. W., Dudfield, M., Witte, K. K., Ingle, L., & Carroll, S. (2016). Submaximal fitness and mortality risk reduction in coronary heart disease: A retrospective cohort study of community-based exercise rehabilitation. BMJ open, 6(6), Article e011125. https://doi.org/10.1136/bmjopen-2016-011125

Objectives To examine the association between submaximal cardiorespiratory fitness (sCRF) and all-cause mortality in a cardiac rehabilitation (CR) cohort. Design Retrospective cohort study of participants entering CR between 26 May 1993 and 16 Octob... Read More about Submaximal fitness and mortality risk reduction in coronary heart disease: A retrospective cohort study of community-based exercise rehabilitation.

A clinician's guide to cardiopulmonary exercise testing 2: test interpretation (2015)
Journal Article
Nichols, S., Taylor, C., & Ingle, L. (2015). A clinician's guide to cardiopulmonary exercise testing 2: test interpretation. British journal of hospital medicine, 76(5), 281-289. https://doi.org/10.12968/hmed.2015.76.5.281

Data obtained from cardiopulmonary exercise testing offer additional interpretive power over conventional exercise tolerance testing. When used correctly, these data allow improved clinical decision making in patients with cardiometabolic and respira... Read More about A clinician's guide to cardiopulmonary exercise testing 2: test interpretation.

A clinician's guide to cardiopulmonary exercise testing 1: An introduction (2015)
Journal Article
Nichols, S., Taylor, C., & Ingle, L. (2015). A clinician's guide to cardiopulmonary exercise testing 1: An introduction. British journal of hospital medicine, 76(4), 192-195. https://doi.org/10.12968/hmed.2015.76.4.192

Compared to standard exercise tolerance testing, cardiopulmonary exercise testing is a reliable and powerful tool that can be used for risk stratification, exercise prescription and clinical diagnosis.