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Long-term Clinical and Cost-effectiveness of Early Endovenous Ablation in Venous Ulceration: A Randomized Clinical Trial (2020)
Journal Article
Gohel, M. S., Mora, MSc, J., Szigeti, M., Epstein, D. M., Heatley, F., Bradbury, A., …Davies, A. H. (in press). Long-term Clinical and Cost-effectiveness of Early Endovenous Ablation in Venous Ulceration: A Randomized Clinical Trial. JAMA Surgery, https://doi.org/10.1001/jamasurg.2020.3845

Importance One-year outcomes from the Early Venous Reflux Ablation (EVRA) randomized trial showed accelerated venous leg ulcer healing and greater ulcer-free time for participants who are treated with early endovenous ablation of lower extremity sup... Read More about Long-term Clinical and Cost-effectiveness of Early Endovenous Ablation in Venous Ulceration: A Randomized Clinical Trial.

A randomised clinical trial of ultrasound guided cannulation of difficult fistulae for dialysis access (2020)
Journal Article
Latham, R., Smith, G., Chetter, I., Carradice, D., Cai, P., Eves, J., …Lathan, R. (in press). A randomised clinical trial of ultrasound guided cannulation of difficult fistulae for dialysis access. The journal of vascular access, https://doi.org/10.1177/1129729820954725

Background: Arteriovenous fistulae (AVF) are preferred for dialysis access but require accurate cannulation for effective dialysis. Evidence supports improvements in cannulation and complication rates using ultrasound guidance (USG) in cannulating ot... Read More about A randomised clinical trial of ultrasound guided cannulation of difficult fistulae for dialysis access.

Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication (2018)
Journal Article
Harwood, A. E., Totty, J. P., Pymer, S., Huang, C., Hitchman, L., Carradice, D., …Chetter, I. C. (2019). Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication. Journal of vascular surgery, 69(6), 1899-1908.e1. https://doi.org/10.1016/j.jvs.2018.10.065

Objective Intermittent claudication occurs in 20 % of the population over 70 and treatment includes a supervised exercise programme (SEP). Whilst there is evidence demonstrating walking improvements following a SEP there is conflicting data on the ph... Read More about Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication.

Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery (2017)
Journal Article
Carradice, D., Chetter, I. C., Totty, J. P., Wallace, T., Bua, N., Pan, D., & Smith, G. E. (2017). Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery. Annals of vascular surgery, 44, 387-392. https://doi.org/10.1016/j.avsg.2017.03.198

© 2017 Elsevier Inc. Background Dressings coated with dialkylcarbamoyl chloride (DACC) are highly hydrophobic and irreversibly bind multiple types of bacteria, trapping them in the dressing and reducing the number of organisms at the wound surface. W... Read More about Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery.

Long-term outcomes of a randomized clinical trial of supervised exercise, percutaneous transluminal angioplasty or combined treatment for patients with intermittent claudication due to femoropopliteal disease (2017)
Journal Article
Mazari, F. A., Khan, J. A., Samuel, N., Smith, G., Carradice, D., McCollum, P., & Chetter, I. (2017). Long-term outcomes of a randomized clinical trial of supervised exercise, percutaneous transluminal angioplasty or combined treatment for patients with intermittent claudication due to femoropopliteal disease. Journal of vascular surgery, 65(4), 1239-1240. doi:10.1016/j.jvs.2017.02.014

Background: To compare the long-term outcomes of angioplasty (PTA), supervised exercise (SEP) and combined treatment (PTA+SEP) in patients with intermittent claudication (IC) due to femoropopliteal disease. Methods: Patients recruited to PTA, SEP and... Read More about Long-term outcomes of a randomized clinical trial of supervised exercise, percutaneous transluminal angioplasty or combined treatment for patients with intermittent claudication due to femoropopliteal disease.

Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial) (2017)
Journal Article
Harwood, A. E., Smith, G. E., Totty, J. P., Carradice, D., Chetter, I. C., Harwood, A., …Smith, G. (2017). Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial). Trials, 18(1), https://doi.org/10.1186/s13063-017-1844-4

© 2017 The Author(s). Background: Peripheral arterial disease (PAD) has a population prevalence of 4.6% with intermittent claudication (IC) presenting as one of the earliest and most common symptoms. PAD has detrimental effects on patients' walking a... Read More about Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial).

Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review (2017)
Journal Article
Totty, J., Bua, N., Smith, G., Harwood, A., Carradice, D., Wallace, T., & Chetter, I. (2017). Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review. Journal of Wound Care, 26(3), 107-114 . https://doi.org/10.12968/jowc.2017.26.3.107

Objective: Dialkylcarbomoyl chloride (DACC)-coated dressings (Leukomed Sorbact and Cutimed Sorbact) irreversibly bind bacteria at the wound surface that are then removed when the dressing is changed. They are a recent addition to the wound care profe... Read More about Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review.

A systematic review of management of inadvertent arterial injury during central venous catheterisation (2016)
Journal Article
Dixon, O. G. B., Smith, G. E., Carradice, D., & Chetter, I. C. (2017). A systematic review of management of inadvertent arterial injury during central venous catheterisation. The journal of vascular access, 18(2), 97-102. https://doi.org/10.5301/jva.5000611

© 2017 Wichtig Publishing. Introduction: Central venous catheterisation (CVC) is a technique commonly used to obtain vascular access and over five million CVCs are inserted annually. This systematic review of CVC-related arterial injury aims to compa... Read More about A systematic review of management of inadvertent arterial injury during central venous catheterisation.

A systematic review and meta-analysis of systemic intraoperative anticoagulation during arteriovenous access formation for dialysis (2015)
Journal Article
Smith, G. E., Souroullos, P., Cayton, T., Harwood, A., Carradice, D., & Chetter, I. C. (2016). A systematic review and meta-analysis of systemic intraoperative anticoagulation during arteriovenous access formation for dialysis. The journal of vascular access, 17(1), 1-5 . https://doi.org/10.5301/jva.5000484

Purpose: Surgical arteriovenous fistula (AVF) or graft (AVG) is preferred to a central venous catheter for dialysis access. Surgical access may suffer thrombosis early after placement and systemic anticoagulation during surgical access formation may... Read More about A systematic review and meta-analysis of systemic intraoperative anticoagulation during arteriovenous access formation for dialysis.

Systematic review of compression following treatment for varicose veins (2015)
Journal Article
El-Sheikha, J., Carradice, D., Nandhra, S., Leung, C., Smith, G., Campbell, B., & Chetter, I. (2015). Systematic review of compression following treatment for varicose veins. British journal of surgery : BJS, 102(7), 719-725. https://doi.org/10.1002/bjs.9788

Background Consensus regarding compression following treatment of varicose veins has yet to be reached. This systematic review aims to establish the optimal compression regimen after venous treatment. Methods A systematic review of MEDLINE, Embase an... Read More about Systematic review of compression following treatment for varicose veins.

A randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins (2015)
Journal Article
Nandhra, S., El-sheikha, J., Carradice, D., Wallace, T., Souroullas, P., Samuel, N., …Chetter, I. C. (2015). A randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins. Journal of vascular surgery, 61(3), 741-746. https://doi.org/10.1016/j.jvs.2014.09.037

Background: This randomized clinical trial compared endovenous laser ablation (EVLA) and surgical ligation with attempted stripping in the treatment of small saphenous vein (SSV) insufficiency. The early results demonstrated that EVLA was more likely... Read More about A randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins.

Compression regimes after endovenous ablation for superficial venous insufficiency – A survey of members of the Vascular Society of Great Britain and Ireland (2015)
Journal Article
El-Sheikha, J., Nandhra, S., Carradice, D., Acey, C., Smith, G., Campbell, B., & Chetter, I. (2016). Compression regimes after endovenous ablation for superficial venous insufficiency – A survey of members of the Vascular Society of Great Britain and Ireland. Phlebology, 31(1), 16-22. https://doi.org/10.1177/0268355514567732

Introduction: The optimal compression regime following ultrasound guided foam sclerotherapy (UGFS), radiofrequency ablation (RFA) and endovenous laser ablation (EVLA) for varicose veins is not known. The aim of this study was to document current prac... Read More about Compression regimes after endovenous ablation for superficial venous insufficiency – A survey of members of the Vascular Society of Great Britain and Ireland.

A comparison of the effectiveness of treating those with and without the complications of superficial venous insufficiency (2014)
Journal Article
Carradice, D., Wallace, T., Gohil, R., & Chetter, I. (2014). A comparison of the effectiveness of treating those with and without the complications of superficial venous insufficiency. Annals of Surgery, 260(2), 396-401. https://doi.org/10.1097/sla.0000000000000541

Objective: To test the hypothesis that patients with soft tissue changes related to superficial venous insufficiency (SVI) have greater benefits from treatment than those with only symptomatic varicose veins. Background: A commonly held view is that... Read More about A comparison of the effectiveness of treating those with and without the complications of superficial venous insufficiency.

Clinical outcomes and quality of life 5 years after a randomized trial of concomitant or sequential phlebectomy following endovenous laser ablation for varicose veins (2014)
Journal Article
El-Sheikha, J., Nandhra, S., Carradice, D., Wallace, T., Samuel, N., Smith, G., & Chetter, I. C. (2014). Clinical outcomes and quality of life 5 years after a randomized trial of concomitant or sequential phlebectomy following endovenous laser ablation for varicose veins. British journal of surgery : BJS, 101(9), 1093-1097. https://doi.org/10.1002/bjs.9565

BackgroundEndovenous laser ablation (EVLA) is a popular treatment for superficial venous insufficiency. Debate continues regarding the optimal management of symptomatic varicose tributaries following ablation of the main saphenous trunk. This randomi... Read More about Clinical outcomes and quality of life 5 years after a randomized trial of concomitant or sequential phlebectomy following endovenous laser ablation for varicose veins.

Economic analysis of a randomized trial of percutaneous angioplasty, supervised exercise or combined treatment for intermittent claudication due to femoropopliteal arterial disease (2013)
Journal Article
Mazari, F. A. K., Khan, J. A., Carradice, D., Samuel, N., Gohil, R., McCollum, P. T., & Chetter, I. C. (2013). Economic analysis of a randomized trial of percutaneous angioplasty, supervised exercise or combined treatment for intermittent claudication due to femoropopliteal arterial disease. British journal of surgery : BJS, 100(9), 1172-1179. https://doi.org/10.1002/bjs.9200

BackgroundThe aim was to compare costs and utilities of percutaneous transluminal angioplasty (PTA), a supervised exercise programme (SEP) and combined treatment (PTA + SEP) in patients with intermittent claudication (IC) to establish the most cost-e... Read More about Economic analysis of a randomized trial of percutaneous angioplasty, supervised exercise or combined treatment for intermittent claudication due to femoropopliteal arterial disease.

Comparison of 12-W versus 14-W endovenous laser ablation in the treatment of great saphenous varicose veins: 5-year outcomes from a randomized controlled trial (2013)
Journal Article
Samuel, N., Wallace, T., Carradice, D., Mazari, F. A., & Chetter, I. C. (2013). Comparison of 12-W versus 14-W endovenous laser ablation in the treatment of great saphenous varicose veins: 5-year outcomes from a randomized controlled trial. Vascular and endovascular surgery, 47(5), 346-352. https://doi.org/10.1177/1538574413487265

Introduction: Endovenous laser ablation (EVLA) has been demonstrated to be an effective treatment for lower limb varicose veins in the short and midterm results. This study reports the 5-year outcomes of EVLA technique at different power settings. Me... Read More about Comparison of 12-W versus 14-W endovenous laser ablation in the treatment of great saphenous varicose veins: 5-year outcomes from a randomized controlled trial.

Randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins (2013)
Journal Article
Samuel, N., Carradice, D., Wallace, T., Mekako, A., Hatfield, J., & Chetter, I. (2013). Randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins. Annals of Surgery, 257(3), 419-426. https://doi.org/10.1097/SLA.0b013e318275f4e4

Introduction: No randomized clinical trial comparing treatment options for small saphenous vein (SSV) incompetence exists, and there is no clear evidence that this axis behaves the same as the great saphenous vein after treatment. This means that the... Read More about Randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins.