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All Outputs (15)

One evidence base; three stories: do opioids relieve chronic breathlessness? (2017)
Journal Article
Ekstrom, M., Currow, D. C., Johnson, M. J., Ekström, M., Bajwah, S., Bland, J. M., …Johnson, M. (2018). One evidence base; three stories: do opioids relieve chronic breathlessness?. Thorax, 73(1), 88-90. https://doi.org/10.1136/thoraxjnl-2016-209868

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/. The efficacy of low-dose systemic opioids for chronic br... Read More about One evidence base; three stories: do opioids relieve chronic breathlessness?.

Insights from Australians with respiratory disease living in the community with experience of self-managing through an emergency department 'near miss' for breathlessness: A strengths-based qualitative study (2017)
Journal Article
Luckett, T., Phillips, J., Johnson, M., Garcia, M., Bhattarai, P., Carrieri-Kohlman, V., …Davidson, P. M. (2017). Insights from Australians with respiratory disease living in the community with experience of self-managing through an emergency department 'near miss' for breathlessness: A strengths-based qualitative study. BMJ open, 7(12), e017536. https://doi.org/10.1136/bmjopen-2017-017536

Objectives Breathlessness ‘crises’ in people with chronic respiratory conditions are a common precipitant for emergency department (ED) presentations, many of which might be avoided through improved self-management and support. This study sought insi... Read More about Insights from Australians with respiratory disease living in the community with experience of self-managing through an emergency department 'near miss' for breathlessness: A strengths-based qualitative study.

Psychometric validation of the needs assessment tool: Progressive disease in interstitial lung disease (2017)
Journal Article
Johnson, M. J., Jamali, A., Ross, J., Fairhurst, C., Boland, J., Reigada, C., …Yorke, J. (2018). Psychometric validation of the needs assessment tool: Progressive disease in interstitial lung disease. Thorax, 73(9), 880-883. https://doi.org/10.1136/thoraxjnl-2017-210911

© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. The inter-rater/test-retest reliability and construct validity... Read More about Psychometric validation of the needs assessment tool: Progressive disease in interstitial lung disease.

Conference presentation in palliative medicine: Predictors of subsequent publication (2017)
Journal Article
Hanchanale, S., Kerr, M., Ashwood, P., Curran, E., Ekstrom, M., Allen, S., …Johnson, M. J. (2018). Conference presentation in palliative medicine: Predictors of subsequent publication. BMJ Supportive & Palliative Care, 8(1), 73-77. https://doi.org/10.1136/bmjspcare-2017-001425

© 2018 Article author(s) (or their employer(s) unless otherwise stated in the text of the article). All rights reserved. Objectives Concerns have been raised about poor-quality palliative care research and low publication rate from conference abstrac... Read More about Conference presentation in palliative medicine: Predictors of subsequent publication.

The independent association of overweight and obesity with breathlessness in adults: a cross-sectional, population-based study (2017)
Journal Article
Currow, D. C., Dal Grande, E., Sidhu, C., Ekström, M., & Johnson, M. J. (2017). The independent association of overweight and obesity with breathlessness in adults: a cross-sectional, population-based study. European respiratory journal, 50(3), Article 1700558. https://doi.org/10.1183/13993003.00558-2017

Obesity is an independent risk factor for chronic breathlessness and should be assessed in people with this symptom.

Pharmacovigilance in hospice/palliative care: Net effect of haloperidol for nausea or vomiting (2017)
Journal Article
Digges, M., Hussein, A., Wilcock, A., Crawford, G. B., Boland, J. W., Agar, M. R., …Johnson, M. J. (2018). Pharmacovigilance in hospice/palliative care: Net effect of haloperidol for nausea or vomiting. Journal of palliative medicine, 21(1), 37-43. https://doi.org/10.1089/jpm.2017.0159

Background Haloperidol is widely prescribed as an anti-emetic in patients receiving palliative care, but there is limited evidence to support and refine its use. Objective To explore the immediate and short-term net clinical effects of haloperidol wh... Read More about Pharmacovigilance in hospice/palliative care: Net effect of haloperidol for nausea or vomiting.

ROMANA 3: a phase 3 safety extension study of anamorelin in advanced non-small-cell lung cancer (NSCLC) patients with cachexia (2017)
Journal Article
Currow, D., Temel, J. S., Abernethy, A., Milanowski, J., Friend, J., & Fearon, K. C. (2017). ROMANA 3: a phase 3 safety extension study of anamorelin in advanced non-small-cell lung cancer (NSCLC) patients with cachexia. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, 28(8), 1949-1956. https://doi.org/10.1093/annonc/mdx192

© The Author 2017. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. Background: Cancer anorexia-cachexia is a debilitating condition frequently observed in NSCLC patients, characterized... Read More about ROMANA 3: a phase 3 safety extension study of anamorelin in advanced non-small-cell lung cancer (NSCLC) patients with cachexia.

A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol (2017)
Journal Article
Currow, D., Watts, G. J., Johnson, M., McDonald, C. F., Miners, J. O., Somogyi, A. A., …Ekström, M. (2017). A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol. BMJ open, 7(7), 1-18. https://doi.org/10.1136/bmjopen-2017-018100

© Article author(s). Introduction Chronic breathlessness is highly prevalent and distressing to patients and families. No medication is registered for its symptomatic reduction. The strongest evidence is for regular, low-dose, extended-release (ER) o... Read More about A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol.

The complex relationship between household income of family caregivers, access to palliative care services and place of death: A national household population survey (2017)
Journal Article
Chen, H., Currow, D. C., Dunn, L., Johnson, M. J., Macleod, U., & Allgar, V. (2018). The complex relationship between household income of family caregivers, access to palliative care services and place of death: A national household population survey. Palliative medicine, 32(2), 357-365. https://doi.org/10.1177/0269216317711825

Background: Previous work shows that more affluent patients with cancer are more likely to die at home, whereas those dying from non-cancer conditions are more likely to die in hospital. Family caregivers are an important factor in determining place... Read More about The complex relationship between household income of family caregivers, access to palliative care services and place of death: A national household population survey.

Effect of opioids and benzodiazepines on clinical outcomes in patients receiving palliative care: an exploratory analysis (2017)
Journal Article
Boland, J. W., Allgar, V., Boland, E. G., Oviasu, O., Agar, M., Currow, D. C., & Johnson, M. J. (2017). Effect of opioids and benzodiazepines on clinical outcomes in patients receiving palliative care: an exploratory analysis. Journal of palliative medicine, 20(11), 1274-1279. https://doi.org/10.1089/jpm.2017.0129

Background: Medications for symptom management in palliative care have associated, but poorly understood, harms. Drug-related harms have important clinical implications, may impact on patients’ compliance and contribute to symptoms. Objective: To exp... Read More about Effect of opioids and benzodiazepines on clinical outcomes in patients receiving palliative care: an exploratory analysis.

Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review (2017)
Journal Article
Hussain, J. A., Johnson, M. J., Currow, D. C., White, I. R., Currow, D., Hussain, J., …White, I. (2017). Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review. Journal of clinical epidemiology, 88, 81-91. https://doi.org/10.1016/j.jclinepi.2017.05.009

Objectives Assess (i) the quality of reporting and handling of missing data (MD) in palliative care trials, (ii) whether there are differences in the reporting of criteria specified by the Consolidated Standards of Reporting Trials (CONSORT) 2010 sta... Read More about Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review.

Towards an expert consensus to delineate a clinical syndrome of chronic breathlessness (2017)
Journal Article
Johnson, M. J., Yorke, J., Hansen-Flaschen, J., Lansing, R., Ekström, M., Similowski, T., & Currow, D. (2017). Towards an expert consensus to delineate a clinical syndrome of chronic breathlessness. European respiratory journal, 49(5), Article 1602277. https://doi.org/10.1183/13993003.02277-2016

Copyright ©ERS 2017. Breathlessness that persists despite treatment for the underlying conditions is debilitating. Identifying this discrete entity as a clinical syndrome should raise awareness amongst patients, clinicians, service providers, researc... Read More about Towards an expert consensus to delineate a clinical syndrome of chronic breathlessness.

Chronic breathlessness associated with poorer physical and mental health-related quality of life (SF-12) across all adult age groups (2017)
Journal Article
Currow, D. C., Johnson, M. J., Dal Grande, E., Ekström, M., Ferreira, D., & McCaffrey, N. (2017). Chronic breathlessness associated with poorer physical and mental health-related quality of life (SF-12) across all adult age groups. Thorax, 72(12), 1151-1153. https://doi.org/10.1136/thoraxjnl-2016-209908

© 2017 Published by the BMJ Publishing Group Limited. Little is known about the impact of chronic breathlessness (modified Medical Research Council (mMRC) score ≥2 for most days, at least three of the last six months) on health-related quality of lif... Read More about Chronic breathlessness associated with poorer physical and mental health-related quality of life (SF-12) across all adult age groups.

Non-opioid medications for the relief of chronic breathlessness: current evidence (2017)
Journal Article
Barbetta, C., Currow, D. C., & Johnson, M. J. (2017). Non-opioid medications for the relief of chronic breathlessness: current evidence. Expert Review of Respiratory Medicine, 11(4), 333-341. https://doi.org/10.1080/17476348.2017.1305896

Introduction: To evaluate systematically randomised clinical trials investigating non-opioid medications for the management and treatment of chronic breathlessness. Areas covered: The evidence for the role of benzodiazepines, anxiolytics, selective s... Read More about Non-opioid medications for the relief of chronic breathlessness: current evidence.

Efficacy of oral risperidone, haloperidol, or placebo for symptoms of delirium among patients in palliative care: A randomized clinical trial (2017)
Journal Article
Agar, M. R., Lawlor, P. G., Quinn, S., Draper, B., Caplan, G. A., Rowett, D., …Currow, D. C. (2017). Efficacy of oral risperidone, haloperidol, or placebo for symptoms of delirium among patients in palliative care: A randomized clinical trial. JAMA Internal Medicine, 177(1), 34-42. https://doi.org/10.1001/jamainternmed.2016.7491

IMPORTANCE Antipsychotics are widely used for distressing symptoms of delirium, but efficacy has not been established in placebo-controlled trials in palliative care. OBJECTIVE To determine efficacy of risperidone or haloperidol relative to placebo i... Read More about Efficacy of oral risperidone, haloperidol, or placebo for symptoms of delirium among patients in palliative care: A randomized clinical trial.