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Mapping arginine methylation in the human body and cardiac disease (2016)
Journal Article
Onwuli, D. O., Cawthorne, C., Beltran-Alvarez, P., Cawthorne, C., Onwuli, D., & Rigau-Roca, L. (2017). Mapping arginine methylation in the human body and cardiac disease. Proteomics. Clinical applications, 11(1-2), 1600106. https://doi.org/10.1002/prca.201600106

Purpose Arginine methylation (ArgMe) is one of the most ubiquitous post-translational modifications, and hundreds of proteins undergo ArgMe in e.g. brain. However, the scope of ArgMe in many tissues, including the heart, is currently under explored.... Read More

An update on transcriptional and post-translational regulation of brain voltage-gated sodium channels (2015)
Journal Article
Beltran-Alvarez, P., & Onwuli, D. O. (2016). An update on transcriptional and post-translational regulation of brain voltage-gated sodium channels. Amino acids, 48(3), 641-651. https://doi.org/10.1007/s00726-015-2122-y

Voltage-gated sodium channels are essential proteins in brain physiology, as they generate the sodium currents that initiate neuronal action potentials. Voltage-gated sodium channels expression, localisation and function are regulated by a range of t... Read More