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Microplastics in human urine: characterisation using µFTIR and sampling challenges using healthy donors and endometriosis participants. (2024)
Journal Article
Rotchell, J. M., Austin, C., Chapman, E., Atherall, C. A., Liddle, C. R., Dunstan, T. S., …Guinn, B. (2024). Microplastics in human urine: characterisation using µFTIR and sampling challenges using healthy donors and endometriosis participants. Ecotoxicology and environmental safety, 274, Article 116208. https://doi.org/10.1016/j.ecoenv.2024.116208

Microplastics (MPs) are found in all environments, within the human food chain, and have been recently detected in several human tissues. The objective herein was to undertake an analysis of MP contamination in human urine samples, from healthy indiv... Read More about Microplastics in human urine: characterisation using µFTIR and sampling challenges using healthy donors and endometriosis participants..

Cytotoxic effects of Ridolfia segetum (L.) Moris phytoproducts in cancer cells (2020)
Journal Article
Beeby, E., Magalhães, M., Lemos, M. F. L., Pires, I. M., & Cabral, C. (in press). Cytotoxic effects of Ridolfia segetum (L.) Moris phytoproducts in cancer cells. Journal of Ethnopharmacology, Article 113515. https://doi.org/10.1016/j.jep.2020.113515

Ethnopharmacological relevance: The past few years have witnessed an increasing interest in essential oils (EOs) as potential therapeutic agents against a wide variety of pathologies, including cancer. EOs extracted from Ridolfia segetum (L.) Moris (... Read More about Cytotoxic effects of Ridolfia segetum (L.) Moris phytoproducts in cancer cells.

Secondary metabolites (essential oils) from sand-dune plants induce cytotoxic effects in cancer cells (2020)
Journal Article
Beeby, E., Magalhães, M., Poças, J., Collins, T., Lemos, M., Barros, L., …Pires, I. M. (2020). Secondary metabolites (essential oils) from sand-dune plants induce cytotoxic effects in cancer cells. Journal of Ethnopharmacology, 258, Article 112803. https://doi.org/10.1016/j.jep.2020.112803

Ethnopharmacological relevance: Despite advances in modern therapeutic strategies, cancer remains the second leading cause of death worldwide. Therefore, there is a constant need to develop more efficient anticancer targeting strategies. The anticanc... Read More about Secondary metabolites (essential oils) from sand-dune plants induce cytotoxic effects in cancer cells.

WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer (2018)
Journal Article
Poujade, F., Mannion, A., Brittain, N., Theodosi, A., Beeby, E., Leszczynska, K. B., …Pires, I. M. (2018). WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer. The British Journal of Cancer, 118(9), 1229-1237. https://doi.org/10.1038/s41416-018-0056-3

© 2018 Cancer Research UK. Background: Metastatic spread is responsible for the majority of cancer-associated deaths. The tumour microenvironment, including hypoxia, is a major driver of metastasis. The aim of this study was to investigate the role o... Read More about WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer.

Low molecular weight heparin suppresses tissue factor-mediated cancer cell invasion and migration in vitro (2011)
Journal Article
Ettelaie, C., Fountain, D., Collier, M. E. W., Beeby, E., Xiao, Y. P., & Maraveyas, A. (2011). Low molecular weight heparin suppresses tissue factor-mediated cancer cell invasion and migration in vitro. Experimental and Therapeutic Medicine, 2(2), 363-367. https://doi.org/10.3892/etm.2011.211

Elevated expression of tissue factor (TF) has been associated with an increased risk of thrombosis in the majority of cancers. Moreover, treatment of cancer patients with low molecular weight heparin (LMWH) appears to have beneficial effects that rea... Read More about Low molecular weight heparin suppresses tissue factor-mediated cancer cell invasion and migration in vitro.