All Outputs (378)

Diseases and impairments as risk factors for onset of disability in the older population in England and Wales: Findings from the medical research council cognitive function and ageing study (2005)
Journal Article
Spiers, N. A., Matthews, R. J., Jagger, C., Matthews, F. E., Boult, C., Robinson, T. G., & Brayne, C. (2005). Diseases and impairments as risk factors for onset of disability in the older population in England and Wales: Findings from the medical research council cognitive function and ageing study. The journals of gerontology. Series A, Biological sciences and medical sciences, 60(2), 248-254. https://doi.org/10.1093/gerona/60.2.248

Background. This paper reports the association between self-reported diseases and impairments and 2-year onset of disability in a prospective study of people aged 65 years or older in five urban and rural centers in England and Wales (Medical Researc... Read More about Diseases and impairments as risk factors for onset of disability in the older population in England and Wales: Findings from the medical research council cognitive function and ageing study.

A systematic literature review of attrition between waves in longitudinal studies in the elderly shows a consistent pattern of dropout between differing studies (2005)
Journal Article
Chatfield, M. D., Brayne, C. E., & Matthews, F. E. (2005). A systematic literature review of attrition between waves in longitudinal studies in the elderly shows a consistent pattern of dropout between differing studies. Journal of clinical epidemiology, 58(1), 13-19. https://doi.org/10.1016/j.jclinepi.2004.05.006

Longitudinal studies of the elderly are complicated by the loss of individuals between waves due to death or other dropout mechanisms. Factors that affect dropout may well be similar from one study to another. This article systematically reviews all... Read More about A systematic literature review of attrition between waves in longitudinal studies in the elderly shows a consistent pattern of dropout between differing studies.

Challenges in the epidemiological investigation of the relationships between physical activity, obesity, diabetes, dementia and depression (2005)
Presentation / Conference Contribution
Brayne, C., Gao, L., & Matthews, F. Challenges in the epidemiological investigation of the relationships between physical activity, obesity, diabetes, dementia and depression

There are many challenges facing epidemiologists wishing to investigate relationships between physical activity, obesity, diabetes, dementia and depression, all of which are complex fields in their own right. There is a large literature investigating... Read More about Challenges in the epidemiological investigation of the relationships between physical activity, obesity, diabetes, dementia and depression.

Comparison of the pathology of cerebral white matter with post-mortem magnetic resonance imaging (MRI) in the elderly brain (2004)
Journal Article
Fernando, M. S., O'Brien, J. T., Perry, R. H., English, P., Forster, G., McMeekin, W., Slade, J. Y., Golkhar, A., Matthews, F. E., Barber, R., Kalaria, R. N., & Ince, P. G. (2004). Comparison of the pathology of cerebral white matter with post-mortem magnetic resonance imaging (MRI) in the elderly brain. Neuropathology and Applied Neurobiology, 30(4), 385-395. https://doi.org/10.1111/j.1365-2990.2004.00550.x

White matter lesions (WML) on magnetic resonance imaging (MRI) brain scans are associated with ageing. They are unrelated to specific disorders, and their impact on cognitive and other brain functions is poorly characterized. Pathological studies oft... Read More about Comparison of the pathology of cerebral white matter with post-mortem magnetic resonance imaging (MRI) in the elderly brain.

The cervical cancer epidemic that screening has prevented in the UK (2004)
Journal Article
Peto, P. J., Gilham, P. C., Fletcher, O., & Matthews, F. E. (2004). The cervical cancer epidemic that screening has prevented in the UK. Lancet, 364(9430), 249-256. https://doi.org/10.1016/S0140-6736%2804%2916674-9

Background Recent reports suggest that the reduction in mortality achieved by the UK national cervical screening programme is too small to justify its financial and psychosocial costs, except perhaps in a few high-risk women. Methods We analysed tren... Read More about The cervical cancer epidemic that screening has prevented in the UK.

Attrition and bias in the MRC cognitive function and ageing study: An epidemiological investigation (2004)
Journal Article
Matthews, F. E., Chatfield, M., Freeman, C., McCracken, C., & Brayne, C. (2004). Attrition and bias in the MRC cognitive function and ageing study: An epidemiological investigation. BMC public health, 4, 1-27. https://doi.org/10.1186/1471-2458-4-12

Background: Any hypothesis in longitudinal studies may be affected by attrition and poor response rates. The MRC Cognitive Function and Ageing study (MRC CFAS) is a population based longitudinal study in five centres with identical methodology in Eng... Read More about Attrition and bias in the MRC cognitive function and ageing study: An epidemiological investigation.

Performance and normative values of a concise neuropsychological test (CAMCOG) in an elderly population sample (2003)
Journal Article
Williams, J. G., Huppert, F. A., Matthews, F. E., & Nickson, J. (2003). Performance and normative values of a concise neuropsychological test (CAMCOG) in an elderly population sample. International journal of geriatric psychiatry, 18(7), 631-644. https://doi.org/10.1002/gps.886

Background: CAMCOG is a widely used brief neuropsychological test. To date no normative values are available for English speaking individuals representative of the general population. Objectives: The aims of the study were to describe the population... Read More about Performance and normative values of a concise neuropsychological test (CAMCOG) in an elderly population sample.

Gender Differences in Life Expectancy Free of Impairment at Older Ages (2002)
Journal Article
Jagger, C., & Matthews, F. (2002). Gender Differences in Life Expectancy Free of Impairment at Older Ages. Journal of Women and Aging, 14(1-2), 85-97. https://doi.org/10.1300/J074v14n01_06

This article uses data from the United Kingdom Medical Research Council Cognitive Function and Ageing study (MRC CFAS) to analyze morbidity associated with three areas of impairment. We use cognitive status, functional status, and physical illness to... Read More about Gender Differences in Life Expectancy Free of Impairment at Older Ages.

Prevalence of dementia in institutional care (2002)
Journal Article
Matthews, F. E., & Dening, T. (2002). Prevalence of dementia in institutional care. Lancet, 360(9328), 225-226. https://doi.org/10.1016/S0140-6736%2802%2909461-8

Information about dementia prevalence in residential and nursing care homes helps these institutions to meet residents' needs. We combined residential characteristics ascertained at a screening interview in 1991-93 with dementia diagnoses from assess... Read More about Prevalence of dementia in institutional care.

Pathological correlates of dementia [3] (multiple letters) (2002)
Journal Article
Kay, D. W., Roth, M., Ince, P. G., Matthews, F., & Bayne, C. (2002). Pathological correlates of dementia [3] (multiple letters). Lancet, 359(9306), 624-625. https://doi.org/10.1016/S0140-6736%2802%2907724-3

The Pulsair 3000 tonometer - How many readings need to be taken to ensure accuracy of the average? (2001)
Journal Article
McCaghrey, G. E., & Matthews, F. E. (2001). The Pulsair 3000 tonometer - How many readings need to be taken to ensure accuracy of the average?. Ophthalmic and Physiological Optics, 21(4), 334-338. https://doi.org/10.1016/S0275-5408%2800%2900040-5

Manufacturers of non-contact tonometers recommend that a number of readings are taken on each eye, and an average obtained. With the Keeler Pulsair 3000 it is advised to take four readings, and average these. This report analyses readings in 100 subj... Read More about The Pulsair 3000 tonometer - How many readings need to be taken to ensure accuracy of the average?.

Health and ill-health in the older population in England and Wales (2001)
Journal Article
Brayne, C., Matthews, F. E., McGee, M. A., & Jagger, C. (2001). Health and ill-health in the older population in England and Wales. Age and ageing, 30(1), 53-62. https://doi.org/10.1093/ageing/30.1.53

Objective: to provide a profile of disorders and disabilities in the older population. Design: the MRC CFAS drew population samples of people aged 64 years and over from Family Health Service Authority lists at five sites and asked participants about... Read More about Health and ill-health in the older population in England and Wales.

Cancer mortality in relatives of women with breast cancer: The OPCS study (1996)
Journal Article
Peto, J., Easton, D. F., Matthews, F. E., Ford, D., & Swerdlow, A. J. (1996). Cancer mortality in relatives of women with breast cancer: The OPCS study. International journal of cancer. Journal international du cancer, 65(3), 275-283. https://doi.org/10.1002/%28SICI%291097-0215%2819960126%2965%3A3%3C275%3A%3AAID-IJC1%3E3.0.CO%3B2-X

Mortality from cancer and other causes in male and female first-degree relatives of women with breast cancer diagnosed before age 60 has been examined in a large population-based cohort study, providing estimates of familial risks free from ascertain... Read More about Cancer mortality in relatives of women with breast cancer: The OPCS study.

Cancer mortality in relatives of women with ovarian cancer: The OPCS study (1996)
Journal Article
Easton, D. F., Matthews, F. E., Ford, D., Swerdlow, A. J., & Peto, J. (1996). Cancer mortality in relatives of women with ovarian cancer: The OPCS study. International journal of cancer. Journal international du cancer, 65(3), 284-294. https://doi.org/10.1002/%28SICI%291097-0215%2819960126%2965%3A3%3C284%3A%3AAID-IJC2%3E3.0.CO%3B2-W

Mortality from cancer and other causes in first-degree relatives of women with ovarian cancer diagnosed before age 60 has been examined in a large population-based cohort study in England and Wales. Relatives of 1,188 ovarian-cancer cases diagnosed b... Read More about Cancer mortality in relatives of women with ovarian cancer: The OPCS study.

Continuing increase in mesothelioma mortality in Britain (1995)
Journal Article
Peto, J., Matthews, F. E., Hodgson, J. T., & Jones, J. R. (1995). Continuing increase in mesothelioma mortality in Britain. Lancet, 345(8949), 535-539. https://doi.org/10.1016/S0140-6736%2895%2990462-X

Mesothelioma is closely related to exposure to asbestos, and mesothelioma mortality can be taken as an index of past exposure to asbestos in the population. We analysed mesothelioma mortality since 1968 to assess the current state of the mesothelioma... Read More about Continuing increase in mesothelioma mortality in Britain.

Rural population mixing and childhood leukaemia: Effects of the North Sea oil industry in Scotland, including the area near Dounreay nuclear site (1993)
Journal Article
Kinlen, L. J., O'Brien, F., Clarke, K., Balkwill, A., & Matthews, F. (1993). Rural population mixing and childhood leukaemia: Effects of the North Sea oil industry in Scotland, including the area near Dounreay nuclear site. https://doi.org/10.1136/bmj.306.6880.743

Objective - To determine if any excess of childhood leukaemia and non-Hodgkin's lymphoma was associated with certain striking examples of population mixing in rural Scotland produced by the North Sea oil industry. Design - Details were traced for ove... Read More about Rural population mixing and childhood leukaemia: Effects of the North Sea oil industry in Scotland, including the area near Dounreay nuclear site.

Clinical evaluation of a range of autorefractors (1993)
Journal Article
McCaghrey, G. E., & Matthews, F. E. (1993). Clinical evaluation of a range of autorefractors. Ophthalmic and Physiological Optics, 13(2), 129-137. https://doi.org/10.1111/j.1475-1313.1993.tb00441.x

A practice‐based study of nine autorefractors was undertaken lo assess reliability and validity. Various statistical methods were used to test aspects of validity of the machines compared with one another. In routine optometric practice the autorefra... Read More about Clinical evaluation of a range of autorefractors.

Cancer mortality in the first degree relatives of young breast cancer patients (1992)
Journal Article
Anderson, K. E., Easton, D. F., Matthews, F. E., & Peto, J. (1992). Cancer mortality in the first degree relatives of young breast cancer patients. The British Journal of Cancer, 66(3), 599-602. https://doi.org/10.1038/bjc.1992.321

In a retrospective cohort study, the mothers and sisters of 740 breast cancer patients aged under 36 at diagnosis have been studied for mortality and cancer incidence. Significantly increased breast cancer mortality was observed below age 60 (30 deat... Read More about Cancer mortality in the first degree relatives of young breast cancer patients.