All Outputs (2)

Regulation of the stem cell marker CD133 is independent of promoter hypermethylation in human epithelial differentiation and cancer (2011)
Journal Article
Pellacani, D., Packer, R. J., Frame, F. M., Oldridge, E. E., Berry, P. A., Labarthe, M.-C., Stower, M. J., Simms, M. S., Collins, A. T., & Maitland, N. J. (2011). Regulation of the stem cell marker CD133 is independent of promoter hypermethylation in human epithelial differentiation and cancer. Molecular Cancer, 10(1), Article 94. https://doi.org/10.1186/1476-4598-10-94

Background
Epigenetic control is essential for maintenance of tissue hierarchy and correct differentiation. In cancer, this hierarchical structure is altered and epigenetic control deregulated, but the relationship between these two phenomena is sti... Read More about Regulation of the stem cell marker CD133 is independent of promoter hypermethylation in human epithelial differentiation and cancer.

Prostate cancer stem cells: do they have a basal or luminal phenotype? (2011)
Journal Article
Maitland, N. J., Frame, F. M., Polson, E. S., Lewis, J. L., & Collins, A. T. (2011). Prostate cancer stem cells: do they have a basal or luminal phenotype?. Hormones and Cancer, 2(1), 47-61. https://doi.org/10.1007/s12672-010-0058-y

The prostate is a luminal secretory tissue whose function is regulated by male sex hormones. Castration produces involution of the prostate to a reversible basal state, and as the majority of prostate cancers also have a luminal phenotype, drug-induc... Read More about Prostate cancer stem cells: do they have a basal or luminal phenotype?.