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All Outputs (11)

Blinding trachoma in postconflict southern Sudan (2006)
Journal Article
Ngondi, J., Ole-Sempele, F., Onsarigo, A., Matende, I., Baba, S., Reacher, M., Matthews, F., Brayne, C., & Emerson, P. (2006). Blinding trachoma in postconflict southern Sudan. PLoS Medicine, 3(12), 2424-2430. https://doi.org/10.1371/journal.pmed.0030478

Background: Trachoma is a leading cause of preventable blindness. Reports from eye surgery camps and anecdotal data indicated that blinding trachoma is a serious cause of visual impairment in Mankien payam (district) of southern Sudan. We conducted t... Read More about Blinding trachoma in postconflict southern Sudan.

Self-rated health status as a predictor of death, functional and cognitive impairment: A longitudinal cohort study (2006)
Journal Article
Bond, J., Dickinson, H. O., Matthews, F., Jagger, C., & Brayne, C. (2006). Self-rated health status as a predictor of death, functional and cognitive impairment: A longitudinal cohort study. European Journal of Ageing, 3(4), 193-206. https://doi.org/10.1007/s10433-006-0039-8

Understanding the prognostic capacity of a simple measure of self-rated health (SRH) by older people becomes increasingly important as the population ages. SRH has been shown to predict survival, functional status and service use. The relationship wi... Read More about Self-rated health status as a predictor of death, functional and cognitive impairment: A longitudinal cohort study.

Dementia before death in ageing societies - The promise of prevention and the reality (2006)
Journal Article
Brayne, C., Gao, L., Dewey, M., & Matthews, F. E. (2006). Dementia before death in ageing societies - The promise of prevention and the reality. PLoS Medicine, 3(10), 1922-1930. https://doi.org/10.1371/journal.pmed.0030397

Background: Dementia and severe cognitive impairment are very closely linked to ageing. The longer we live the more likely we are to suffer from these conditions. Given population increases in longevity it is important to understand not only risk and... Read More about Dementia before death in ageing societies - The promise of prevention and the reality.

The frequency and validity of self-reported diagnosis of Parkinson's disease in the UK elderly: MRC CFAS cohort (2006)
Journal Article
Foltynie, T., Matthews, F. E., Ishihara, L., & Brayne, C. (2006). The frequency and validity of self-reported diagnosis of Parkinson's disease in the UK elderly: MRC CFAS cohort. BMC Neurology, 6, https://doi.org/10.1186/1471-2377-6-29

Background: Estimates of the incidence and prevalence of chronic diseases can be made using established cohort studies but these estimates may have lower reliability if based purely on self-reported diagnosis. Methods: The MRC Cognitive Function & Ag... Read More about The frequency and validity of self-reported diagnosis of Parkinson's disease in the UK elderly: MRC CFAS cohort.

Effect of 3 years of SAFE (surgery, antibiotics, facial cleanliness, and environmental change) strategy for trachoma control in southern Sudan: a cross-sectional study (2006)
Journal Article
Ngondi, J., Onsarigo, A., Matthews, F., Reacher, M., Brayne, C., Baba, S., Solomon, A. W., Zingeser, J., & Emerson, P. M. (2006). Effect of 3 years of SAFE (surgery, antibiotics, facial cleanliness, and environmental change) strategy for trachoma control in southern Sudan: a cross-sectional study. Lancet, 368(9535), 589-595. https://doi.org/10.1016/S0140-6736%2806%2969202-7

Background: A trachoma control programme was started in southern Sudan in 2001. We did a 3-year evaluation to quantify uptake of SAFE (surgery, antibiotics, facial cleanliness, and environmental change) interventions, and to assess the prevalence of... Read More about Effect of 3 years of SAFE (surgery, antibiotics, facial cleanliness, and environmental change) strategy for trachoma control in southern Sudan: a cross-sectional study.

An investigation of whether factors associated with short-term attrition change or persist over ten years: Data from the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) (2006)
Journal Article
Matthews, F. E., Chatfield, M., & Brayne, C. (2006). An investigation of whether factors associated with short-term attrition change or persist over ten years: Data from the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS). BMC public health, 6, https://doi.org/10.1186/1471-2458-6-185

Background: Factors associated with the loss of participants in long-term longitudinal studies of ageing, due to refusal or moves, have been discussed less than those with short term follow-up. Methods: In a population-based study of cognition and ag... Read More about An investigation of whether factors associated with short-term attrition change or persist over ten years: Data from the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS).

White matter lesions in an unselected cohort of the elderly: Molecular pathology suggests origin from chronic hypoperfusion injury (2006)
Journal Article
Fernando, M. S., Simpson, J. E., Matthews, F., Brayne, C., Lewis, C. E., Barber, R., Kalaria, R. N., Forster, G., Esteves, F., Wharton, S. B., Shaw, P. J., O'Brien, J. T., & Ince, P. G. (2006). White matter lesions in an unselected cohort of the elderly: Molecular pathology suggests origin from chronic hypoperfusion injury. Stroke, 37(6), 1391-1398. https://doi.org/10.1161/01.STR.0000221308.94473.14

BACKGROUND AND PURPOSE - "Incidental" MRI white matter (WM) lesions, comprising periventricular lesions (PVLs) and deep subcortical lesions (DSCLs), are common in the aging brain. Direct evidence of ischemia associated with incidental WM lesions (WML... Read More about White matter lesions in an unselected cohort of the elderly: Molecular pathology suggests origin from chronic hypoperfusion injury.

Regional differences in multidimensional aspects of health: Findings from the MRC cognitive function and ageing study (2006)
Journal Article
Matthews, F. E., Miller, L. L., Brayne, C., & Jagger, C. (2006). Regional differences in multidimensional aspects of health: Findings from the MRC cognitive function and ageing study. BMC public health, 6, https://doi.org/10.1186/1471-2458-6-90

Background: Differences in mortality and health experience across regions are well recognised and UK government policy aims to address this inequality. Methods combining life expectancy and health have concentrated on specific areas, such as self-per... Read More about Regional differences in multidimensional aspects of health: Findings from the MRC cognitive function and ageing study.

Risk factors for incident dementia in England and Wales: The Medical Research Council Cognitive Function and Ageing Study. A population-based nested case-control study (2006)
Journal Article
Yip, A. G., Brayne, C., & Matthews, F. E. (2006). Risk factors for incident dementia in England and Wales: The Medical Research Council Cognitive Function and Ageing Study. A population-based nested case-control study. Age and ageing, 35(2), 154-160. https://doi.org/10.1093/ageing/afj030

Objective: To investigate a number of prospectively collected factors (sociodemographic, medical and behavioural) and their association with incident dementia in a population-based cohort. Design: Nested case-control analysis (at 2 and 6 years) of a... Read More about Risk factors for incident dementia in England and Wales: The Medical Research Council Cognitive Function and Ageing Study. A population-based nested case-control study.

Prevalence and causes of blindness and low vision in southern Sudan (2006)
Journal Article
Ngondi, J., Ole-Sempele, F., Onsarigo, A., Matende, I., Baba, S., Reacher, M., Matthews, F., Brayne, C., & Emerson, P. M. (2006). Prevalence and causes of blindness and low vision in southern Sudan. PLoS Medicine, 3(12), 2416-2423. https://doi.org/10.1371/journal.pmed.0030477

Background: Blindness and low vision are thought to be common in southern Sudan. However, the magnitude and geographical distribution are largely unknown. We aimed to estimate the prevalence of blindness and low vision, identify the main causes of bl... Read More about Prevalence and causes of blindness and low vision in southern Sudan.