University of Hull logo

Increasing access to integrated ESKD care as part of Universal Health Coverage (2019)
Journal Article
Yao, Q., Walker, R., Walker, R. C., Vachharajani, T., Tungsanga, K., Trask, M., …Murtagh, F. (2019). Increasing access to integrated ESKD care as part of Universal Health Coverage. Kidney International, 95(4), S1-S33. https://doi.org/10.1016/j.kint.2018.12.005

The global nephrology community recognizes the need for a cohesive strategy to address the growing problem of end-stage kidney disease (ESKD). In March 2018, the International Society of Nephrology hosted a summit on integrated ESKD care, including 9... Read More

Socioeconomic position and use of health care in the last year of life: a systematic review and meta-analysis (2019)
Journal Article
Davies, J. M., Sleeman, K. E., Leniz, J., Wilson, R., Higginson, I. J., Verne, J., …Murtagh, F. (in press). Socioeconomic position and use of health care in the last year of life: a systematic review and meta-analysis. PLoS Medicine,

Background Low socioeconomic position (SEP) is recognized as a risk factor for worse health outcomes. How socioeconomic factors influence end of life care, and the magnitude of their effect, is not understood. This review aimed to synthesise and qua... Read More

Patients’ views on care and their association with outcomes in palliative care (2019)
Journal Article
Firth, A. M., Pinto, C., Firth, A. M., Groeneveld, E. I., Guo, P., Sykes, N., & Murtagh, F. E. (2019). Patients’ views on care and their association with outcomes in palliative care. Palliative medicine, https://doi.org/10.1177/0269216319831383

When patients face advanced illness, their experience of care is especially important. In palliative care, we often rely on the accounts of bereaved relatives to report the quality of end-of-life care, and there are no validated patient-reported meas... Read More

The views and experiences of older people with conservatively managed renal failure: A qualitative study of communication, information and decision-making (2019)
Journal Article
Selman, L. E., Bristowe, K., Higginson, I. J., & Murtagh, F. E. M. (2019). The views and experiences of older people with conservatively managed renal failure: A qualitative study of communication, information and decision-making. BMC Nephrology, 20(1), 1-12. doi:10.1186/s12882-019-1230-4

Background: Older people with advanced kidney disease require information and support from clinicians when deciding whether to have dialysis or conservative (non-dialysis) care. There is evidence that communication practices, information provision an... Read More

Invisible and intangible illness: a qualitative interview study of patients’ experiences and understandings of conservatively managed end-stage kidney disease (2019)
Journal Article
Bristowe, K., Selman, L. E., Higginson, I. J., & Murtagh, F. E. M. (2019). Invisible and intangible illness: a qualitative interview study of patients’ experiences and understandings of conservatively managed end-stage kidney disease. Annals of palliative medicine, 8, doi:10.21037/apm.2018.12.06

Background: Increasing numbers of older adults are living with kidney disease. For those with comorbidities, conservative management of end-stage kidney disease is a viable option: dialysis may afford limited or no survival benefit, and perceived bur... Read More

Finding a ‘new normal’ following acute illness: A qualitative study of influences on frail older people’s care preferences (2018)
Journal Article
Etkind, S. N., Lovell, N., Nicholson, C. J., Higginson, I. J., & Murtagh, F. E. (2019). Finding a ‘new normal’ following acute illness: A qualitative study of influences on frail older people’s care preferences. Palliative medicine, 33(3), 301-311. doi:10.1177/0269216318817706

Background: The frail older population is growing, and many frail older people have episodes of acute illness. Patient preferences are increasingly considered important in the delivery of person-centred care and may change following acute illness. Ai... Read More

Perspectives of patients, family caregivers and health professionals on the use of outcome measures in palliative care and lessons for implementation: a multi-method qualitative study (2018)
Journal Article
Pinto, C., Bristowe, K., Witt, J., Davies, J., de Wolf-Linder, S., Dawkins, M., …Murtagh, F. (in press). Perspectives of patients, family caregivers and health professionals on the use of outcome measures in palliative care and lessons for implementation: a multi-method qualitative study. Annals of palliative medicine, 7(s3), S137-S150. doi:10.21037/apm.2018.09.02

Background: Routine use of outcome measures in palliative care is recommended to demonstrate and improve quality of care. The use of outcome measures is relatively recent in UK specialist palliative care services and understanding their use in practi... Read More

The conceptual models and mechanisms of action that underpin advance care planning for cancer patients: A systematic review of randomised controlled trials (2018)
Journal Article
Lin, C., Evans, C. J., Koffman, J., Armes, J., Murtagh, F. E., & Harding, R. (2019). The conceptual models and mechanisms of action that underpin advance care planning for cancer patients: A systematic review of randomised controlled trials. Palliative medicine, 33(1), 5-23. doi:10.1177/0269216318809582

Background: No systematic review has focused on conceptual models underpinning advance care planning for patients with advanced cancer, and the mechanisms of action in relation to the intended outcomes. Aim: To appraise conceptual models and develop... Read More

Symptoms and concerns among children and young people with life-limiting and life-threatening conditions: A systematic review highlighting meaningful health outcomes (2018)
Journal Article
Namisango, E., Bristowe, K., Allsop, M. J., Murtagh, F. E., Abas, M., Higginson, I. J., …Harding, R. (2019). Symptoms and concerns among children and young people with life-limiting and life-threatening conditions: A systematic review highlighting meaningful health outcomes. Patient, 12(1), 15-55. doi:10.1007/s40271-018-0333-5

Background The design and provision of quality pediatric palliative care should prioritize issues that matter to children and their families for optimal outcomes. Objective This review aims to identify symptoms, concerns and outcomes that matter to... Read More

Does advance care planning in addition to usual care reduce hospitalisation for patients with advanced heart failure: A systematic review and narrative synthesis (2018)
Journal Article
Kernick, L., Hogg, K., Millerick, Y., Murtagh, F., Djahit, A., & Johnson, M. (2018). Does advance care planning in addition to usual care reduce hospitalisation for patients with advanced heart failure: A systematic review and narrative synthesis. Palliative medicine, 32(10), 1539-1551. doi:10.1177/0269216318801162

BACKGROUND: People with advanced heart failure have repeated hospital admissions. Advance care planning can support patient preferences, but studies in people with heart failure have not been assessed. AIM: To evaluate the literature regarding advan... Read More

Does advance care planning in addition to usual care reduce hospitalisation for patients with advanced heart failure: A systematic review and narrative synthesis (2018)
Journal Article
Kernick, L. A., Hogg, K. J., Millerick, Y., Murtagh, F. E., Djahit, A., & Johnson, M. (2018). Does advance care planning in addition to usual care reduce hospitalisation for patients with advanced heart failure: A systematic review and narrative synthesis. Palliative medicine, 32(10), 1539-1551. doi:10.1177/0269216318801162

© The Author(s) 2018. Background: People with advanced heart failure have repeated hospital admissions. Advance care planning can support patient preferences, but studies in people with heart failure have not been assessed. Aim: To evaluate the liter... Read More

What are the main palliative care symptoms and concerns of older people with multimorbidity?—a comparative cross-sectional study using routinely collected Phase of Illness, Australia-modified Karnofsky Performance Status and Integrated Palliative Care Out (2018)
Journal Article
Nicholson, C., Davies, J. M., George, R., Smith, B., Pace, V., Harris, L., …Murtagh, F. E. M. (2018). What are the main palliative care symptoms and concerns of older people with multimorbidity?—a comparative cross-sectional study using routinely collected Phase of Illness, Australia-modified Karnofsky Performance Status and Integrated Palliative Care Outcome Scale data. Annals of palliative medicine, 7(Supplement 3), S164-S175. doi:10.21037/apm.2018.06.07

BACKGROUND: Older people with multimorbidities are projected to be the main recipients of palliative care in the coming decades. However, because their specific palliative care needs are poorly understood and service response is underdeveloped, older... Read More

Advance care planning with patients who have end-stage kidney disease: A systematic realist review (2018)
Journal Article
O'Halloran, P., Noble, H., Norwood, K., Maxwell, P., Shields, J., Fogarty, D., …Brazil, K. (2018). Advance care planning with patients who have end-stage kidney disease: A systematic realist review. Journal of pain and symptom management, 56(5), 795-807.e18. doi:10.1016/j.jpainsymman.2018.07.008

Context Patients with end-stage kidney disease have a high mortality rate and disease burden. Despite this, many do not speak with health care professionals about end-of-life issues. Advance care planning is recommended in this context but is complex... Read More

Patient empowerment, what does it mean for adults in the advanced stages of a life-limiting illness: A systematic review using critical interpretive synthesis (2018)
Journal Article
Wakefield, D., Bayly, J., Selman, L. E., Firth, A. M., Higginson, I. J., & Murtagh, F. E. (2018). Patient empowerment, what does it mean for adults in the advanced stages of a life-limiting illness: A systematic review using critical interpretive synthesis. Palliative medicine, 32(8), 1288-1304. doi:10.1177/0269216318783919

© The Author(s) 2018. Background: Patient empowerment, defined as ‘a process through which people gain greater control over decisions and actions affecting their health’ (World Health Organization) is a key theme within global health and social care... Read More

Taking patient and public involvement online: qualitative evaluation of an online forum for palliative care and rehabilitation research (2018)
Journal Article
Brighton, L. J., Pask, S., Benalia, H., Bailey, S., Sumerfield, M., Witt, J., …Evans, C. J. (2018). Taking patient and public involvement online: qualitative evaluation of an online forum for palliative care and rehabilitation research. Research Involvement and Engagement, 4(1), doi:10.1186/s40900-018-0097-z. ISSN 2056-7529

Background Patient and public involvement (PPI) in research is increasingly recognised as important. Most PPI activities take place face-to-face, yet this can be difficult for people with ill health or caring responsibilities, and may exclude people... Read More

Validation of the IPOS-Renal Symptom Survey in advanced kidney disease; a cross-sectional study (2018)
Journal Article
Raj, R., Ahuja, K., Frandsen, M., Murtagh, F. E. M., & Jose, M. (in press). Validation of the IPOS-Renal Symptom Survey in advanced kidney disease; a cross-sectional study. Journal of pain and symptom management, ISSN 0885-3924

Context: The significant symptom burden in advanced renal disease is often poorly recognized by clinicians. Recently, the Integrated Palliative Outcome Score (IPOS) – Renal survey was developed from pre-existing tools to capture these symptoms and... Read More

Influences on care preferences of older people with advanced illness: a systematic review and thematic synthesis (2018)
Journal Article
Etkind, S. N., Bone, A. E., Lovell, N., Higginson, I. J., & Murtagh, F. E. (2018). Influences on care preferences of older people with advanced illness: a systematic review and thematic synthesis. Journal of the American Geriatrics Society, 66(5), 1031-1039. doi:10.1111/jgs.15272

Objectives To determine and explore the influences on care preferences of older people with advanced illness and integrate our results into a model to guide practice and research. Design Systematic review using Medline, Embase, PsychINFO, Web of S... Read More

Comparison of survival among older adults with kidney failure treated versus not treated with chronic dialysis (2018)
Journal Article
Tam-Tham, H., Quinn, R. R., Weaver, R. G., Zhang, J., Ravani, P., Liu, P., …Hemmelgarn, B. R. (in press). Comparison of survival among older adults with kidney failure treated versus not treated with chronic dialysis. Kidney International, ISSN 0085-2538

Prior comparisons of survival between dialysis and non-dialysis care for older adults with kidney failure are limited to those managed by nephrologists, and are vulnerable to lead and immortal time biases. We compared time to all-cause mortality amon... Read More

Development and validation of a casemix classification to predict costs of specialist palliative care provision across inpatient hospice, hospital and community settings in the UK: a study protocol (2018)
Journal Article
O'Brien, S. M., Guo, P., Dzingina, M., Firth, A. M., Davies, J. M., Douiri, A., …Murtagh, F. E. (2018). Development and validation of a casemix classification to predict costs of specialist palliative care provision across inpatient hospice, hospital and community settings in the UK: a study protocol. BMJ open, 8(3), (e020071). doi:10.1136/bmjopen-2017-020071. ISSN 2044-6055

Introduction Provision of palliative care is inequitable with wide variations across conditions and settings in the UK. Lack of a standard way to classify by case complexity is one of the principle obstacles to addressing this. We aim to develop and... Read More

A framework for complexity in palliative care: A qualitative study with patients, family carers and professionals (2018)
Journal Article
Pask, S., Pinto, C., Bristowe, K., van Vliet, L., Nicholson, C., Evans, C. J., …Murtagh, F. E. (2018). A framework for complexity in palliative care: A qualitative study with patients, family carers and professionals. Palliative medicine, 32(6), 1078-1090. doi:10.1177/0269216318757622

Background: Palliative care patients are often described as complex but evidence on complexity is limited. We need to understand complexity, including at individual patient-level, to define specialist palliative care, characterise palliative care pop... Read More