All Outputs (151)

Perspectives of patients, family caregivers and health professionals on the use of outcome measures in palliative care and lessons for implementation: a multi-method qualitative study (2018)
Journal Article
Pinto, C., Bristowe, K., Witt, J., Davies, J. M., de Wolf-Linder, S., Dawkins, M., Guo, P., Higginson, I. J., Daveson, B., & Murtagh, F. E. (2018). Perspectives of patients, family caregivers and health professionals on the use of outcome measures in palliative care and lessons for implementation: a multi-method qualitative study. Annals of palliative medicine, 7(s3), S137-S150. https://doi.org/10.21037/apm.2018.09.02

Background: Routine use of outcome measures in palliative care is recommended to demonstrate and improve quality of care. The use of outcome measures is relatively recent in UK specialist palliative care services and understanding their use in practi... Read More about Perspectives of patients, family caregivers and health professionals on the use of outcome measures in palliative care and lessons for implementation: a multi-method qualitative study.

Does advance care planning in addition to usual care reduce hospitalisation for patients with advanced heart failure: A systematic review and narrative synthesis (2018)
Journal Article
Kernick, L., Hogg, K., Millerick, Y., Murtagh, F., Djahit, A., & Johnson, M. (2018). Does advance care planning in addition to usual care reduce hospitalisation for patients with advanced heart failure: A systematic review and narrative synthesis. Palliative medicine, 32(10), 1539-1551. https://doi.org/10.1177/0269216318801162

BACKGROUND: People with advanced heart failure have repeated hospital admissions. Advance care planning can support patient preferences, but studies in people with heart failure have not been assessed.
AIM: To evaluate the literature regarding advan... Read More about Does advance care planning in addition to usual care reduce hospitalisation for patients with advanced heart failure: A systematic review and narrative synthesis.

Validation of the IPOS-Renal Symptom Survey in advanced kidney disease; a cross-sectional study (2018)
Journal Article
Raj, R., Ahuja, K., Frandsen, M., Murtagh, F. E., & Jose, M. (2018). Validation of the IPOS-Renal Symptom Survey in advanced kidney disease; a cross-sectional study. Journal of pain and symptom management, 56(2), 281-287. https://doi.org/10.1016/j.jpainsymman.2018.04.006

Context:
The significant symptom burden in advanced renal disease is often poorly recognized by clinicians. Recently, the Integrated Palliative Outcome Score (IPOS) – Renal survey was developed from pre-existing tools to capture these symptoms and o... Read More about Validation of the IPOS-Renal Symptom Survey in advanced kidney disease; a cross-sectional study.

What are the main palliative care symptoms and concerns of older people with multimorbidity?—a comparative cross-sectional study using routinely collected Phase of Illness, Australia-modified Karnofsky Performance Status and Integrated Palliative Care Outcome Scale data (2018)
Journal Article
Nicholson, C., Davies, J. M., George, R., Smith, B., Pace, V., Harris, L., Ross, J., Noble, J., Hansford, P., & Murtagh, F. E. (2018). What are the main palliative care symptoms and concerns of older people with multimorbidity?—a comparative cross-sectional study using routinely collected Phase of Illness, Australia-modified Karnofsky Performance Status and Integrated Palliative Care Outcome Scale data. Annals of palliative medicine, 7(Supplement 3), S164-S175. https://doi.org/10.21037/apm.2018.06.07

BACKGROUND: Older people with multimorbidities are projected to be the main recipients of palliative care in the coming decades. However, because their specific palliative care needs are poorly understood and service response is underdeveloped, older... Read More about What are the main palliative care symptoms and concerns of older people with multimorbidity?—a comparative cross-sectional study using routinely collected Phase of Illness, Australia-modified Karnofsky Performance Status and Integrated Palliative Care Outcome Scale data.

Advance care planning with patients who have end-stage kidney disease: A systematic realist review (2018)
Journal Article
O'Halloran, P., Noble, H., Norwood, K., Maxwell, P., Shields, J., Fogarty, D., Murtagh, F., Morton, R., & Brazil, K. (2018). Advance care planning with patients who have end-stage kidney disease: A systematic realist review. Journal of pain and symptom management, 56(5), 795-807.e18. https://doi.org/10.1016/j.jpainsymman.2018.07.008

Context
Patients with end-stage kidney disease have a high mortality rate and disease burden. Despite this, many do not speak with health care professionals about end-of-life issues. Advance care planning is recommended in this context but is complex... Read More about Advance care planning with patients who have end-stage kidney disease: A systematic realist review.

Patient empowerment, what does it mean for adults in the advanced stages of a life-limiting illness: A systematic review using critical interpretive synthesis (2018)
Journal Article
Wakefield, D., Bayly, J., Selman, L. E., Firth, A. M., Higginson, I. J., & Murtagh, F. E. M. (2018). Patient empowerment, what does it mean for adults in the advanced stages of a life-limiting illness: A systematic review using critical interpretive synthesis. Palliative medicine, 32(8), 1288-1304. https://doi.org/10.1177/0269216318783919

© The Author(s) 2018. Background: Patient empowerment, defined as ‘a process through which people gain greater control over decisions and actions affecting their health’ (World Health Organization) is a key theme within global health and social care... Read More about Patient empowerment, what does it mean for adults in the advanced stages of a life-limiting illness: A systematic review using critical interpretive synthesis.

Survival among older adults with kidney failure is better in the first three years with chronic dialysis treatment than not (2018)
Journal Article
Tam-Tham, H., Quinn, R. R., Weaver, R. G., Zhang, J., Ravani, P., Liu, P., Thomas, C., King-Shier, K., Fruetel, K., James, M. T., Manns, B. J., Tonelli, M., Murtagh, F. E., & Hemmelgarn, B. R. (2018). Survival among older adults with kidney failure is better in the first three years with chronic dialysis treatment than not. Kidney International, 94(3), 582-588. https://doi.org/10.1016/j.kint.2018.03.007

Comparisons of survival between dialysis and nondialysis care for older adults with kidney failure have been limited to those managed by nephrologists, and are vulnerable to lead and immortal time biases. So we compared time to all-cause mortality am... Read More about Survival among older adults with kidney failure is better in the first three years with chronic dialysis treatment than not.

Taking patient and public involvement online: Qualitative evaluation of an online forum for palliative care and rehabilitation research (2018)
Journal Article
Brighton, L. J., Pask, S., Benalia, H., Bailey, S., Sumerfield, M., Witt, J., de Wolf-Linder, S., Etkind, S. N., Murtagh, F. E., Koffman, J., & Evans, C. J. (2018). Taking patient and public involvement online: Qualitative evaluation of an online forum for palliative care and rehabilitation research. Research Involvement and Engagement, 4(1), Article 14. https://doi.org/10.1186/s40900-018-0097-z

Background
Patient and public involvement (PPI) in research is increasingly recognised as important. Most PPI activities take place face-to-face, yet this can be difficult for people with ill health or caring responsibilities, and may exclude people... Read More about Taking patient and public involvement online: Qualitative evaluation of an online forum for palliative care and rehabilitation research.

Development and validation of a casemix classification to predict costs of specialist palliative care provision across inpatient hospice, hospital and community settings in the UK: a study protocol (2018)
Journal Article
Guo, P., Dzingina, M., Firth, A. M., Davies, J. M., Douiri, A., O'Brien, S. M., Pinto, C., Pask, S., Higginson, I. J., Eagar, K., & Murtagh, F. E. (2018). Development and validation of a casemix classification to predict costs of specialist palliative care provision across inpatient hospice, hospital and community settings in the UK: a study protocol. BMJ open, 8(3), e020071. https://doi.org/10.1136/bmjopen-2017-020071

Introduction Provision of palliative care is inequitable with wide variations across conditions and settings in the UK. Lack of a standard way to classify by case complexity is one of the principle obstacles to addressing this. We aim to develop and... Read More about Development and validation of a casemix classification to predict costs of specialist palliative care provision across inpatient hospice, hospital and community settings in the UK: a study protocol.

Influences on care preferences of older people with advanced illness: a systematic review and thematic synthesis (2018)
Journal Article
Etkind, S. N., Bone, A. E., Lovell, N., Higginson, I. J., & Murtagh, F. E. (2018). Influences on care preferences of older people with advanced illness: a systematic review and thematic synthesis. Journal of the American Geriatrics Society, 66(5), 1031-1039. https://doi.org/10.1111/jgs.15272

Objectives

To determine and explore the influences on care preferences of older people with advanced illness and integrate our results into a model to guide practice and research.

Design

Systematic review using Medline, Embase, PsychINFO, Web of S... Read More about Influences on care preferences of older people with advanced illness: a systematic review and thematic synthesis.

A framework for complexity in palliative care: A qualitative study with patients, family carers and professionals (2018)
Journal Article
Pask, S., Pinto, C., Bristowe, K., van Vliet, L., Nicholson, C., Evans, C. J., George, R., Bailey, K., Davies, J. M., Guo, P., Daveson, B. A., Higginson, I. J., & Murtagh, F. E. (2018). A framework for complexity in palliative care: A qualitative study with patients, family carers and professionals. Palliative medicine, 32(6), 1078-1090. https://doi.org/10.1177/0269216318757622

Background:
Palliative care patients are often described as complex but evidence on complexity is limited. We need to understand complexity, including at individual patient-level, to define specialist palliative care, characterise palliative care pop... Read More about A framework for complexity in palliative care: A qualitative study with patients, family carers and professionals.

Social and clinical determinants of preferences and their achievement at the end of life: Prospective cohort study of older adults receiving palliative care in three countries (2017)
Journal Article
Higginson, I. J., Bennett, E., Daveson, B. A., Cooper, F., Morrison, R. S., Yi, D., de Wolf-Linder, S., Meier, D., Dzingina, M., Smith, M., Ellis-Smith, C., Ryan, K., Evans, C., McQuillan, R., Ferguson, T., Normand, C., Henson, L., Johnston, B. M., Murtagh, F. E., Kaler, P., …Wei, G. (2017). Social and clinical determinants of preferences and their achievement at the end of life: Prospective cohort study of older adults receiving palliative care in three countries. BMC Geriatrics, 17(1), https://doi.org/10.1186/s12877-017-0648-4

© 2017 The Author(s). Background: Achieving choice is proposed as a quality marker. But little is known about what influences preferences especially among older adults. We aimed to determine and compare, across three countries, factors associated wit... Read More about Social and clinical determinants of preferences and their achievement at the end of life: Prospective cohort study of older adults receiving palliative care in three countries.

What is the impact of population ageing on the future provision of end-of-life care? Population-based projections of place of death (2017)
Journal Article
Bone, A. E., Gomes, B., Etkind, S. N., Verne, J., Murtagh, F. E., Evans, C. J., & Higginson, I. J. (2018). What is the impact of population ageing on the future provision of end-of-life care? Population-based projections of place of death. Palliative medicine, 32(2), 329-336. https://doi.org/10.1177/0269216317734435

© 2017, © The Author(s) 2017. Background: Population ageing represents a global challenge for future end-of-life care. Given new trends in place of death, it is vital to examine where the rising number of deaths will occur in future years and implica... Read More about What is the impact of population ageing on the future provision of end-of-life care? Population-based projections of place of death.

Prescribing non-opioid drugs in end-stage kidney disease (2017)
Journal Article
Wilcock, A., Charlesworth, S., Twycross, R., Waddington, A., Worthington, O., Murtagh, F. E., Beavis, J., King, S., Mihalyo, M., & Kotlinska-Lemieszek, A. (2017). Prescribing non-opioid drugs in end-stage kidney disease. Journal of pain and symptom management, 54(5), 776-787. https://doi.org/10.1016/j.jpainsymman.2017.08.014

Palliative care services are increasingly involved in the care of patients with chronic kidney disease, either alone or as a comorbid condition. Because renal impairment often changes the pharmacokinetic and/or pharmacodynamic effects of a drug, this... Read More about Prescribing non-opioid drugs in end-stage kidney disease.

Systematic review of pharmacological therapies for the management of ischaemic pain in patients with non-reconstructable critical limb ischaemia (2017)
Journal Article
Laoire, Á. N., & Murtagh, F. E. (2018). Systematic review of pharmacological therapies for the management of ischaemic pain in patients with non-reconstructable critical limb ischaemia. BMJ supportive & palliative care, 8(4), 400-410. https://doi.org/10.1136/bmjspcare-2017-001359

Background Critical limb ischaemia (CLI) is a severe manifestation of peripheral arterial disease, characterised by chronic ischaemic rest pain, ulcers or gangrene. Management of ischaemic pain is challenging in patients with no options for revascula... Read More about Systematic review of pharmacological therapies for the management of ischaemic pain in patients with non-reconstructable critical limb ischaemia.

Phase of Illness in palliative care: Cross-sectional analysis of clinical data from community, hospital and hospice patients (2017)
Journal Article
Mather, H., Guo, P., Firth, A., Davies, J. M., Sykes, N., Landon, A., & Murtagh, F. E. (2018). Phase of Illness in palliative care: Cross-sectional analysis of clinical data from community, hospital and hospice patients. Palliative medicine, 32(2), 404-412. https://doi.org/10.1177/0269216317727157

© 2017, © The Author(s) 2017. Background: Phase of Illness describes stages of advanced illness according to care needs of the individual, family and suitability of care plan. There is limited evidence on its association with other measures of sympto... Read More about Phase of Illness in palliative care: Cross-sectional analysis of clinical data from community, hospital and hospice patients.

Time to improve informed consent for dialysis: an international perspective (2017)
Journal Article
Murtagh, F. E., Brennan, F., Stewart, C., Burgess, H., Davison, S. N., Moss, A. H., Murtagh, F. E. M., Germain, M., Tranter, S., & Brown, M. (2017). Time to improve informed consent for dialysis: an international perspective. Clinical journal of the American Society of Nephrology, 12(6), 1001-1009. https://doi.org/10.2215/CJN.09740916

The literature reveals that current nephrology practice in obtaining informed consent for dialysis falls short of ethical and legal requirements. Meeting these requirements represents a significant challenge, especially because the benefits and risks... Read More about Time to improve informed consent for dialysis: an international perspective.

Development of a core outcome set for disease modification trials in mild to moderate dementia: A systematic review, patient and public consultation and consensus recommendations (2017)
Journal Article
Webster, L., Groskreutz, D., Grinbergs-Saull, A., Howard, R., O’Brien, J. T., Mountain, G., Banerjee, S., Woods, B., Perneczky, R., Lafortune, L., Roberts, C., McCleery, J., Pickett, J., Bunn, F., Challis, D., Charlesworth, G., Featherstone, K., Fox, C., Goodman, C., Jones, R., …Livingston, G. (2017). Development of a core outcome set for disease modification trials in mild to moderate dementia: A systematic review, patient and public consultation and consensus recommendations. Health Technology Assessment, 21(26), 1-192. https://doi.org/10.3310/hta21260

Background: There is currently no disease-modifying treatment available to halt or delay the progression of the disease pathology in dementia. An agreed core set of the best-available and most appropriate outcomes for disease modification would facil... Read More about Development of a core outcome set for disease modification trials in mild to moderate dementia: A systematic review, patient and public consultation and consensus recommendations.

How many people will need palliative care in 2040? Past trends, future projections and implications for services (2017)
Journal Article
Etkind, S. N., Bone, A. E., Gomes, B., Lovell, N., Evans, C. J., Higginson, I. J., & Murtagh, F. E. M. (2017). How many people will need palliative care in 2040? Past trends, future projections and implications for services. BMC medicine, 15(1), https://doi.org/10.1186/s12916-017-0860-2

Background: Current estimates suggest that approximately 75% of people approaching the end-of-life may benefit
from palliative care. The growing numbers of older people and increasing prevalence of chronic illness in many
countries mean that more peo... Read More about How many people will need palliative care in 2040? Past trends, future projections and implications for services.

Strategies to address the shortcomings of commonly used advanced chronic heart failure descriptors to improve recruitment in palliative care research: A parallel mixed-methods feasibility study (2017)
Journal Article
Kane, P. M., Murtagh, F. E., Ryan, K. R., Brice, M., Mahon, N. G., McAdam, B., McQuillan, R., O’Gara, G., Raleigh, C., Tracey, C., Howley, C., Higginson, I. J., Daveson, B. A., & on behalf of BuildCARE. (2018). Strategies to address the shortcomings of commonly used advanced chronic heart failure descriptors to improve recruitment in palliative care research: A parallel mixed-methods feasibility study. Palliative medicine, 32(2), 517-524. https://doi.org/10.1177/0269216317706426

Background:
Recruitment challenges contribute to the paucity of palliative care research with advanced chronic heart failure patients.

Aim:
To describe the challenges and outline strategies of recruiting advanced chronic heart failure patients.

Des... Read More about Strategies to address the shortcomings of commonly used advanced chronic heart failure descriptors to improve recruitment in palliative care research: A parallel mixed-methods feasibility study.