All Outputs (4)

Tuning the relaxation rates of dual-mode T₁/T₂ nanoparticle contrast agents: a study into the ideal system (2015)
Journal Article
Keasberry, N. A., Bañobre-López, M., Wood, C., Stasiuk, G. J., Gallo, J., & Long, N. J. (2015). Tuning the relaxation rates of dual-mode T₁/T₂ nanoparticle contrast agents: a study into the ideal system. Nanoscale, 7(38), 16119-16128. https://doi.org/10.1039/c5nr04400f

Magnetic resonance imaging (MRI) is an excellent imaging modality. However the low sensitivity of the technique poses a challenge to achieving an accurate image of function at the molecular level. To overcome this, contrast agents are used; typically... Read More about Tuning the relaxation rates of dual-mode T₁/T₂ nanoparticle contrast agents: a study into the ideal system.

Pancreatic β-cell imaging in humans: Fiction or option? (2015)
Journal Article
Laurent, D., Vinet, L., Lamprianou, S., Daval, M., Filhoulaud, G., Ktorza, A., …Hecksher-Sørensen, J. (2016). Pancreatic β-cell imaging in humans: Fiction or option?. Diabetes, Obesity and Metabolism, 18(1), 6-15. https://doi.org/10.1111/dom.12544

Diabetes mellitus is a growing worldwide epidemic disease, currently affecting 1 in 12 adults. Treatment of disease complications typically consumes ∼10% of healthcare budgets in developed societies. Whilst immune‐mediated destruction of insulin‐secr... Read More about Pancreatic β-cell imaging in humans: Fiction or option?.

Dual-modal magnetic resonance/fluorescent zinc probes for pancreatic β-cell mass imaging (2015)
Journal Article
Stasiuk, G. J., Minuzzi, F., Sae-Heng, M., Rivas, C., Juretschke, H., Piemonti, L., …Long, N. J. (2015). Dual-modal magnetic resonance/fluorescent zinc probes for pancreatic β-cell mass imaging. Chemistry: a European journal, 21(13), 5023-5033. https://doi.org/10.1002/chem.201406008

Despite the contribution of changes in pancreatic β-cell mass to the development of all forms of diabetes mellitus, few robust approaches currently exist to monitor these changes prospectively in vivo. Although magnetic-resonance imaging (MRI) provid... Read More about Dual-modal magnetic resonance/fluorescent zinc probes for pancreatic β-cell mass imaging.

⁹⁹ᵐTc SPECT imaging agent based on cFLFLFK for the detection of FPR1 in inflammation (2015)
Journal Article
Stasiuk, G. J., Holloway, P. M., Rivas, C., Trigg, W., Luthra, S. K., Morrison Iveson, V., …Long, N. J. (2015). ⁹⁹ᵐTc SPECT imaging agent based on cFLFLFK for the detection of FPR1 in inflammation. Dalton Transactions : an international journal of inorganic chemistry, 44(11), 4986-4993. https://doi.org/10.1039/c4dt02980a

Non-invasive imaging of the inflammatory process can provide a great deal of insight into a wide variety of diseases states, aiding diagnosis, evaluation and effective targeted treatment. During inflammation, blood borne leukocytes are recruited, thr... Read More about ⁹⁹ᵐTc SPECT imaging agent based on cFLFLFK for the detection of FPR1 in inflammation.