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Sacral neuromodulation for the management of severe constipation: development of a constipation treatment protocol (2011)
Journal Article
Sharma, A., Liu, B., Waudby, P., & Duthie, G. S. (2011). Sacral neuromodulation for the management of severe constipation: development of a constipation treatment protocol. International Journal of Colorectal Disease, 26(12), (1583-1587). doi:10.1007/s00384-011-1257-x. ISSN 0179-1958

Background Constipation is a common multifactorial gastrointestinal symptom with quality of life implications. Sacral neuromodulation has been used in the management of severe constipation with mixed results. The aim of this study was to review our... Read More about Sacral neuromodulation for the management of severe constipation: development of a constipation treatment protocol.

Artificial neural networks to predict presence of significant pathology in patients presenting to routine colorectal clinics (2010)
Journal Article
Maslekar, S., Gardiner, A. B., Monson, J. R. T., & Duthie, G. S. (2010). Artificial neural networks to predict presence of significant pathology in patients presenting to routine colorectal clinics. Colorectal Disease, 12(12), 1254-1259. doi:10.1111/j.1463-1318.2009.02005.x

Aim Artificial neural networks (ANNs) are computer programs used to identify complex relations within data. Routine predictions of presence of colorectal pathology based on population statistics have little meaning for individual patient. This result... Read More about Artificial neural networks to predict presence of significant pathology in patients presenting to routine colorectal clinics.

Quality assurance in flexible sigmoidoscopy: Medical and nonmedical endoscopists (2009)
Journal Article
Maslekar, S., Waudby, P., Avery, G., Monson, J. R. T., & Duthie, G. S. (2009). Quality assurance in flexible sigmoidoscopy: Medical and nonmedical endoscopists. Surgical Endoscopy, 24(1), 89-93. doi:10.1007/s00464-009-0553-9

Purpose: The clinical assessment of position in colon and hence completion during flexible sigmoidoscopy (FS) is believed to be inaccurate. The technique of applying endomucosal clips with follow-up X-ray has previously been used for establishing com... Read More about Quality assurance in flexible sigmoidoscopy: Medical and nonmedical endoscopists.

Randomized controlled trial of patient-controlled sedation for colonoscopy: Entonox vs modified patient-maintained target-controlled propofol (2009)
Journal Article
Maslekar, S., Balaji, P., Gardiner, A., Culbert, B., Monson, J. R., & Duthie, G. S. (2011). Randomized controlled trial of patient-controlled sedation for colonoscopy: Entonox vs modified patient-maintained target-controlled propofol. Colorectal Disease, 13(1), 48-57. doi:10.1111/j.1463-1318.2009.01988.x

Aim Propofol sedation is often associated with deep sedation and decreased manoeuvrability. Patient-maintained sedation has been used in such patients with minimal side-effects. We aimed to compare novel modified patient-maintained target-controlled... Read More about Randomized controlled trial of patient-controlled sedation for colonoscopy: Entonox vs modified patient-maintained target-controlled propofol.

Patient satisfaction with lower gastrointestinal endoscopy: doctors, nurse and nonmedical endoscopists (2009)
Journal Article
Maslekar, S., Hughes, M., Gardiner, A., Monson, J. R. T., & Duthie, G. S. (2010). Patient satisfaction with lower gastrointestinal endoscopy: doctors, nurse and nonmedical endoscopists. Colorectal disease, 12(10), 1033-1038. https://doi.org/10.1111/j.1463-1318.2009.01989.x

Aim Assessment of patient satisfaction with lower gastrointestinal endoscopy (LGE) comprising colonoscopy and flexible sigmoidoscopy is gaining increasing importance. We have now trained non healthcare professionals such as nonmedical endoscopists (N... Read More about Patient satisfaction with lower gastrointestinal endoscopy: doctors, nurse and nonmedical endoscopists.

Randomized clinical trial of Entonox versus midazolam-fentanyl sedation for colonoscopy (2009)
Journal Article
Maslekar, S., Gardiner, A., & Duthie, G. (2009). Randomized clinical trial of Entonox versus midazolam-fentanyl sedation for colonoscopy. British journal of surgery, 96(4), 361 - 368. https://doi.org/10.1002/bjs.6467

BACKGROUND Intravenous sedation for colonoscopy is associated with cardiorespiratory complications and delayed recovery. The aim of this randomized clinical trial was to compare the efficacy of Entonox (50 per cent nitrous oxide and 50 per cent oxyge... Read More about Randomized clinical trial of Entonox versus midazolam-fentanyl sedation for colonoscopy.

Quality assurance in colonoscopy: role of endomucosal clips (2009)
Journal Article
Maslekar, S., Avery, G., & Duthie, G. S. (2010). Quality assurance in colonoscopy: role of endomucosal clips. Colorectal Disease, 12(7), 651-656. doi:10.1111/j.1463-1318.2009.01874.x

Objective Quality assurance in colonoscopy is important, and subjective assessment of completion based on endoscopic signs can be inaccurate leading to missed lesions. We aimed to determine the technique of endomucosal clips with follow-up X-rays in... Read More about Quality assurance in colonoscopy: role of endomucosal clips.

Randomized clinical trial of Entonox ® versus midazolam-fentanyl sedation for colonoscopy (2009)
Journal Article
Maslekar, S., Gardiner, A., Hughes, M., Culbert, B., & Duthie, G. S. (2009). Randomized clinical trial of Entonox ® versus midazolam-fentanyl sedation for colonoscopy. British journal of surgery : BJS, 96(4), 361-368. doi:10.1002/bjs.6467

Background: Intravenous sedation for colonoscopy is associated with cardiorespiratory complications and delayed recovery. The aim of this randomized clinical trial was to compare the efficacy of Entonox ® (50 per cent nitrous oxide and 50 per cent o... Read More about Randomized clinical trial of Entonox ® versus midazolam-fentanyl sedation for colonoscopy.

Anterior anal sphincter repair for fecal incontinence: Good longterm results are possible (2006)
Journal Article
Maslekar, S., Gardiner, A. B., & Duthie, G. S. (2007). Anterior anal sphincter repair for fecal incontinence: Good longterm results are possible. Journal of The American College of Surgeons, 204(1), (40-46). doi:10.1016/j.jamcollsurg.2006.10.008. ISSN 1072-7515

Background: Anterior anal sphincter repair (ASR) is standard treatment for fecal incontinence resulting from an obstetrically damaged anal sphincter. Longterm results of repair have generally been shown to be poor. This review of single-unit series a... Read More about Anterior anal sphincter repair for fecal incontinence: Good longterm results are possible.

A new method of assessing anal sphincter integrity using inverted vectormanometry (2006)
Journal Article
Kaur, G., Gardiner, A., & Duthie, G. S. (2006). A new method of assessing anal sphincter integrity using inverted vectormanometry. Diseases of the colon & rectum, 49(8), 1160-1166. doi:10.1007/s10350-006-0556-8

PURPOSE: Vectorgraphy as an integrated mapping of radial pressure profiles of the anal canal has been used to attempt identification of pressure-related defects with doubtful reliability since vectorgraphs bear no resemblance to endoanal ultrasound s... Read More about A new method of assessing anal sphincter integrity using inverted vectormanometry.

Investigation and treatment of faecal incontinence (2006)
Journal Article
Maslekar, S., Gardiner, A., Maklin, C., & Duthie, G. S. (2006). Investigation and treatment of faecal incontinence. Postgraduate Medical Journal, 82(968), 363-371. doi:10.1136/pgmj.2005.044099

Faecal incontinence is a debilitating condition affecting people of all ages, and significantly impairs quality of life. Proper clinical assessment followed by conservative medical therapy leads to improvement in more than 50% of cases, including pat... Read More about Investigation and treatment of faecal incontinence.

Randomised controlled trial of sedation for colonoscopy: Entonox versus intravenous sedation (2006)
Journal Article
Maslekar, S. K., Hughes, M., Skinn, E., Gardiner, A., Culbert, B., & Duthie, G. S. (2006). Randomised controlled trial of sedation for colonoscopy: Entonox versus intravenous sedation. Gastrointestinal Endoscopy, 63(5), AB97. doi:10.1016/j.gie.2006.03.087

Introduction: Intravenous sedation for colonoscopy is associated with cardio-respiratory complications, delayed recovery and prolonged drowsiness. We aimed to determine whether inhaled Entonox

Non-medical colonoscopy (2006)
Journal Article
Maslekar, S. K., Gardiner, A., Hughes, M., & Duthie, G. S. (2006). Non-medical colonoscopy. Gastrointestinal Endoscopy, 63(5), AB114. doi:10.1016/j.gie.2006.03.148

Aims: There is increasing demand for colonoscopy especially with introduction of screening programmes. Though colonoscopy is performed by doctors and nurses, there is an acute shortage of trained colonoscopists

Abstracts of the AGA Institute (2006)
Journal Article
Gardiner, A., Maslekar, S., & Duthie, G. (2006). Abstracts of the AGA Institute. Gastroenterology, 130(4), A-1-A-747. doi:10.1016/s0016-5085(06)60008-5

Aims: Artificial neural networks (ANN) are computer programs used to identify complexrelations within data that cannot be detected with conventional linear-statistical analysis.The routine clinical predictions of need for lower gastrointestinal endos... Read More about Abstracts of the AGA Institute.


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