Sacral neuromodulation for the management of severe constipation: development of a constipation treatment protocol (2011)
Journal Article
Sharma, A., Liu, B., Waudby, P., & Duthie, G. S. (2011). Sacral neuromodulation for the management of severe constipation: development of a constipation treatment protocol. International Journal of Colorectal Disease, 26(12), (1583-1587). doi:10.1007/s00384-011-1257-x. ISSN 0179-1958

Background Constipation is a common multifactorial gastrointestinal symptom with quality of life implications. Sacral neuromodulation has been used in the management of severe constipation with mixed results. The aim of this study was to review our... Read More

Artificial neural networks to predict presence of significant pathology in patients presenting to routine colorectal clinics (2010)
Journal Article
Monson, J. R. T., Gardiner, A. B., Duthie, G. S., Maslekar, S., & Monson, J. R. (2010). Artificial neural networks to predict presence of significant pathology in patients presenting to routine colorectal clinics. Colorectal Disease, 12(12), 1254-1259. doi:10.1111/j.1463-1318.2009.02005.x

Aim Artificial neural networks (ANNs) are computer programs used to identify complex relations within data. Routine predictions of presence of colorectal pathology based on population statistics have little meaning for individual patient. This result... Read More

Quality assurance in flexible sigmoidoscopy: Medical and nonmedical endoscopists (2009)
Journal Article
Avery, G., Waudby, P., Monson, J. R. T., Maslekar, S., & Duthie, G. S. (2009). Quality assurance in flexible sigmoidoscopy: Medical and nonmedical endoscopists. Surgical Endoscopy, 24(1), 89-93. doi:10.1007/s00464-009-0553-9

Purpose: The clinical assessment of position in colon and hence completion during flexible sigmoidoscopy (FS) is believed to be inaccurate. The technique of applying endomucosal clips with follow-up X-ray has previously been used for establishing com... Read More

Patient satisfaction with lower gastrointestinal endoscopy: doctors, nurse and nonmedical endoscopists (2009)
Journal Article
Maslekar, S., Hughes, M., Gardiner, A., Monson, J. R. T., & Duthie, G. S. (2010). Patient satisfaction with lower gastrointestinal endoscopy: doctors, nurse and nonmedical endoscopists. Colorectal disease, 12(10), 1033-1038. doi:10.1111/j.1463-1318.2009.01989.x

Aim Assessment of patient satisfaction with lower gastrointestinal endoscopy (LGE) comprising colonoscopy and flexible sigmoidoscopy is gaining increasing importance. We have now trained non healthcare professionals such as nonmedical endoscopists (N... Read More

Randomized controlled trial of patient-controlled sedation for colonoscopy: Entonox vs modified patient-maintained target-controlled propofol (2009)
Journal Article
Maslekar, S., Balaji, P., Gardiner, A., Culbert, B., Monson, J. R., & Duthie, G. S. (2010). Randomized controlled trial of patient-controlled sedation for colonoscopy: Entonox vs modified patient-maintained target-controlled propofol. Colorectal Disease, 13(1), 48-57. doi:10.1111/j.1463-1318.2009.01988.x

Aim Propofol sedation is often associated with deep sedation and decreased manoeuvrability. Patient-maintained sedation has been used in such patients with minimal side-effects. We aimed to compare novel modified patient-maintained target-controlled... Read More

Randomized clinical trial of Entonox versus midazolam-fentanyl sedation for colonoscopy (2009)
Journal Article
Maslekar, S., Gardiner, A., & Duthie, G. (2009). Randomized clinical trial of Entonox versus midazolam-fentanyl sedation for colonoscopy. British Journal of Surgery, 96(4), (361 - 368). doi:10.1002/bjs.6467. ISSN 1365-2168

BACKGROUND Intravenous sedation for colonoscopy is associated with cardiorespiratory complications and delayed recovery. The aim of this randomized clinical trial was to compare the efficacy of Entonox (50 per cent nitrous oxide and 50 per cent oxyge... Read More

Quality assurance in colonoscopy: role of endomucosal clips (2009)
Journal Article
Maslekar, S., Avery, G., & Duthie, G. S. (2010). Quality assurance in colonoscopy: role of endomucosal clips. Colorectal Disease, 12(7), (651-656). doi:10.1111/j.1463-1318.2009.01874.x. ISSN 1462-8910

Objective Quality assurance in colonoscopy is important, and subjective assessment of completion based on endoscopic signs can be inaccurate leading to missed lesions. We aimed to determine the technique of endomucosal clips with follow-up X-rays in... Read More

Randomized clinical trial of Entonox ® versus midazolam-fentanyl sedation for colonoscopy (2009)
Journal Article
Maslekar, S., Gardiner, A., Hughes, M., Culbert, B., & Duthie, G. S. (2009). Randomized clinical trial of Entonox ® versus midazolam-fentanyl sedation for colonoscopy. British journal of surgery : BJS, 96(4), (361-368). doi:10.1002/bjs.6467. ISSN 0007-1323

Background: Intravenous sedation for colonoscopy is associated with cardiorespiratory complications and delayed recovery. The aim of this randomized clinical trial was to compare the efficacy of Entonox ® (50 per cent nitrous oxide and 50 per cent o... Read More

Rectal irrigation (RI) is a boon for chronic constipation - A prospective review (2008)
Conference Proceeding
Duthie, G., Gardiner, A., & &NA;, . (2008). Rectal irrigation (RI) is a boon for chronic constipation - A prospective review. doi:10.1007/s10350-008-9314-4

Rectal irrigation (RI) in the treatment of disorders of fecal continence - A prospective review (2007)
Conference Proceeding
Duthie, G., Gardiner, A., & &NA;, . (2007). Rectal irrigation (RI) in the treatment of disorders of fecal continence - A prospective review. doi:10.1007/s10350-007-0261-2

Anterior anal sphincter repair for fecal incontinence: Good longterm results are possible (2006)
Journal Article
Maslekar, S., Gardiner, A. B., & Duthie, G. S. (2007). Anterior anal sphincter repair for fecal incontinence: Good longterm results are possible. Journal of The American College of Surgeons, 204(1), (40-46). doi:10.1016/j.jamcollsurg.2006.10.008. ISSN 1072-7515

Background: Anterior anal sphincter repair (ASR) is standard treatment for fecal incontinence resulting from an obstetrically damaged anal sphincter. Longterm results of repair have generally been shown to be poor. This review of single-unit series a... Read More

A new method of assessing anal sphincter integrity using inverted vectormanometry (2006)
Journal Article
Kaur, G., Gardiner, A., & Duthie, G. S. (2006). A new method of assessing anal sphincter integrity using inverted vectormanometry. Diseases of the colon & rectum, 49(8), 1160-1166. doi:10.1007/s10350-006-0556-8

PURPOSE: Vectorgraphy as an integrated mapping of radial pressure profiles of the anal canal has been used to attempt identification of pressure-related defects with doubtful reliability since vectorgraphs bear no resemblance to endoanal ultrasound s... Read More

Investigation and treatment of faecal incontinence (2006)
Journal Article
Maslekar, S., Gardiner, A., Maklin, C., & Duthie, G. S. (2006). Investigation and treatment of faecal incontinence. Postgraduate Medical Journal, 82(968), 363-371. doi:10.1136/pgmj.2005.044099

Faecal incontinence is a debilitating condition affecting people of all ages, and significantly impairs quality of life. Proper clinical assessment followed by conservative medical therapy leads to improvement in more than 50% of cases, including pat... Read More

Non-medical colonscopy is safe and effective: Results from randomised controlled trial (2006)
Conference Proceeding
Duthie, G., Maslekar, S., & Gardiner, A. (2006). Non-medical colonscopy is safe and effective: Results from randomised controlled trial. doi:10.1007/s10350-006-0567-5

Sacral nerve stimulation as primary treatment for faecal incontinence secondary to obstetric anal sphincter damage: Medium and long-term results (2006)
Journal Article
Maslekar, S. K., Duthie, G. S., & Gardiner, A. (2006). Sacral nerve stimulation as primary treatment for faecal incontinence secondary to obstetric anal sphincter damage: Medium and long-term results. Diseases of the colon & rectum, 49(5), 730 - 730. doi:10.1007/s10350-006-0567-5

Use of artificial neural networks to predict need for colonoscopy in patients attending colorectal clinics (2006)
Journal Article
Maslekar, S., Gardiner, A. B., Duthie, G., & &NA;, . (2006). Use of artificial neural networks to predict need for colonoscopy in patients attending colorectal clinics. Diseases of the colon & rectum, 49(5), 707-788. doi:10.1007/s10350-006-0567-5

Abstracts of the AGA Institute (2006)
Journal Article
Gardiner, A., Maslekar, S., & Duthie, G. (2006). Abstracts of the AGA Institute. Gastroenterology, 130(4), (A-1-A-747). doi:10.1016/s0016-5085(06)60008-5. ISSN 0016-5085

Aims: Artificial neural networks (ANN) are computer programs used to identify complexrelations within data that cannot be detected with conventional linear-statistical analysis.The routine clinical predictions of need for lower gastrointestinal endos... Read More

Non-medical colonoscopy (2006)
Journal Article
Maslekar, S. K., Gardiner, A., Hughes, M., & Duthie, G. S. (2006). Non-medical colonoscopy. Gastrointestinal Endoscopy, 63(5), (AB114). doi:10.1016/j.gie.2006.03.148. ISSN 0016-5107

Aims: There is increasing demand for colonoscopy especially with introduction of screening programmes. Though colonoscopy is performed by doctors and nurses, there is an acute shortage of trained colonoscopists

Randomised controlled trial of sedation for colonoscopy: Entonox versus intravenous sedation (2006)
Journal Article
Maslekar, S. K., Hughes, M., Skinn, E., Gardiner, A., Culbert, B., & Duthie, G. S. (2006). Randomised controlled trial of sedation for colonoscopy: Entonox versus intravenous sedation. Gastrointestinal Endoscopy, 63(5), (AB97). doi:10.1016/j.gie.2006.03.087. ISSN 0016-5107

Introduction: Intravenous sedation for colonoscopy is associated with cardio-respiratory complications, delayed recovery and prolonged drowsiness. We aimed to determine whether inhaled Entonox

Impedance planimetry: clinical impedance planimetry (2005)
Book Chapter
Duthie, G. S., & Gardiner, A. B. (2005). Impedance planimetry: clinical impedance planimetry. In S. D. Wexner, A. P. Zbar, & M. Pescatori (Eds.), Complex Anorectal Disorders: Investigation and Management, 105-113. Springer. doi:10.1007/1-84628-057-5_7