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All Outputs (54)

Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction (2023)
Journal Article
Bravington, A., Obita, G., Baddeley, E., Johnson, M., Murtagh, F., Currow, D., …Boland, J. (2023). Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction. PLoS ONE, 18(8), Article e0289501. https://doi.org/10.1371/journal.pone.0289501

Background: Malignant bowel obstruction is experienced by 15% of people with advanced cancer, preventing them from eating and drinking and causing pain, nausea and vomiting. Surgery is not always appropriate. Management options include tube or stent... Read More about Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction.

A non-randomised controlled study to assess the effectiveness of a new proactive multidisciplinary care intervention for older people living with frailty (2023)
Journal Article
Murtagh, F. E., Okoeki, M., Ukoha-kalu, B. O., Khamis, A., Clark, J., Boland, J. W., …Johnson, M. J. (2023). A non-randomised controlled study to assess the effectiveness of a new proactive multidisciplinary care intervention for older people living with frailty. BMC Geriatrics, 23(1), Article 6. https://doi.org/10.1186/s12877-023-03727-2

Background Integrated care may improve outcomes for older people living with frailty. We aimed to assess the effectiveness of a new, anticipatory, multidisciplinary care service in improving the wellbeing and quality of life (QoL) of older people li... Read More about A non-randomised controlled study to assess the effectiveness of a new proactive multidisciplinary care intervention for older people living with frailty.

Parental death: a systematic review of support experiences and needs of children and parent survivors (2022)
Journal Article
Wray, A., Pickwell-Smith, B., Greenley, S., Pask, S., Bamidele, O., Wright, B., …Boland, J. W. (2022). Parental death: a systematic review of support experiences and needs of children and parent survivors. BMJ supportive & palliative care, https://doi.org/10.1136/spcare-2022-003793

Background: Bereaved people need a supportive response from those around them. Knowing children's and surviving parents' needs following parental death is the first step to ensuring a supportive response. However, no systematic review has reported on... Read More about Parental death: a systematic review of support experiences and needs of children and parent survivors.

The range and suitability of outcome measures used in the assessment of palliative treatment for inoperable malignant bowel obstruction: A systematic review (2022)
Journal Article
Seddon, K., Bravington, A., Obita, G., Baddeley, E., Johnson, M. J., Murtagh, F. E., …Boland, J. W. (2022). The range and suitability of outcome measures used in the assessment of palliative treatment for inoperable malignant bowel obstruction: A systematic review. Palliative medicine, 36(9), 1336-1350. https://doi.org/10.1177/02692163221122352

Background: Malignant bowel obstruction, a complication of certain advanced cancers, causes severe symptoms which profoundly affect quality of life. Clinical management remains complex, and outcome assessment is inconsistent. Aim: To identify outc... Read More about The range and suitability of outcome measures used in the assessment of palliative treatment for inoperable malignant bowel obstruction: A systematic review.

Implementation lessons learnt when trialling palliative care interventions in the intensive care unit: relationships between determinants, implementation strategies, and models of delivery-a systematic review protocol (2022)
Journal Article
Meddick-Dyson, S. A., Boland, J. W., Pearson, M., Greenley, S., Gambe, R., Budding, J. R., & Murtagh, F. E. (2022). Implementation lessons learnt when trialling palliative care interventions in the intensive care unit: relationships between determinants, implementation strategies, and models of delivery-a systematic review protocol. Systematic reviews, 11(1), Article 186. https://doi.org/10.1186/s13643-022-02054-8

BACKGROUND: Heterogeneity amongst palliative care interventions in the intensive care unit (ICU) and their outcomes has meant that, even when found to be effective, translation of evidence into practice is hindered. Previous evidence reviews have sug... Read More about Implementation lessons learnt when trialling palliative care interventions in the intensive care unit: relationships between determinants, implementation strategies, and models of delivery-a systematic review protocol.

Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care (2022)
Journal Article
Pearson, M., Jackson, G., Jackson, C., Boland, J., Featherstone, I., Huang, C., …Johnson, M. (2022). Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care. BMJ open, 12(7), Article e060450. https://doi.org/10.1136/bmjopen-2021-060450

INTRODUCTION: Delirium is a complex condition in which altered mental state and cognition causes severe distress and poor clinical outcomes for patients and families, anxiety and stress for the health professionals and support staff providing care, a... Read More about Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care.

Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review (2022)
Journal Article
Baddeley, E., Mann, M., Bravington, A., Johnson, M. J., Currow, D., Murtagh, F. E., …Noble, S. (in press). Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review. Palliative medicine, https://doi.org/10.1177/02692163221081331

Background: Malignant bowel obstruction occurs in up to 50% of people with advanced ovarian and 15% of people with gastrointestinal cancers. Evaluation and comparison of interventions to manage symptoms are hampered by inconsistent evaluations of eff... Read More about Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review.

Risk factors for delirium in adult patients receiving specialist palliative care: A systematic review and meta-analysis (2021)
Journal Article
Featherstone, I., Sheldon, T., Woodhouse, R., Boland, J. W., Hosie, A., Lawlor, P. G., …Johnson, M. (in press). Risk factors for delirium in adult patients receiving specialist palliative care: A systematic review and meta-analysis. Palliative medicine, https://doi.org/10.1177/02692163211065278

Background: Delirium is common and distressing for patients receiving palliative care. Interventions targetting modifiable risk factors in other settings have been shown to prevent delirium. Research on delirium risk factors in palliative care can in... Read More about Risk factors for delirium in adult patients receiving specialist palliative care: A systematic review and meta-analysis.

Implementing person-centred outcome measures (PCOMs) into routine palliative care: A protocol for a mixed-methods process evaluation of the RESOLVE PCOM Implementation Strategy (2021)
Journal Article
Bradshaw, A., Santarelli, M., Khamis, A. M., Sartain, K., Johnson, M., Boland, J., …Murtagh, F. E. (2021). Implementing person-centred outcome measures (PCOMs) into routine palliative care: A protocol for a mixed-methods process evaluation of the RESOLVE PCOM Implementation Strategy. BMJ open, 11(9), Article e051904. https://doi.org/10.1136/bmjopen-2021-051904

Introduction Person-centred outcome measures improve quality of care and patient outcomes but are used inconsistently in palliative care practice. To address this implementation gap, we developed the 'RESOLVE Implementation Strategy'. This protocol d... Read More about Implementing person-centred outcome measures (PCOMs) into routine palliative care: A protocol for a mixed-methods process evaluation of the RESOLVE PCOM Implementation Strategy.

Outcomes and measures of delirium interventional studies in palliative care to inform a core outcome set: A systematic review (2021)
Journal Article
Agar, M. R., Siddiqi, N., Hosie, A., Boland, J. W., Johnson, M. J., Featherstone, I., …Rose, L. (2021). Outcomes and measures of delirium interventional studies in palliative care to inform a core outcome set: A systematic review. Palliative medicine, 35(10), 1761-1775. https://doi.org/10.1177/02692163211040186

Background: Trials of interventions for delirium in various patient populations report disparate outcomes and measures but little is known about those used in palliative care trials. A core outcome set promotes consistency of outcome selection and me... Read More about Outcomes and measures of delirium interventional studies in palliative care to inform a core outcome set: A systematic review.

Clinical Predictors for Analgesic Response to Radiotherapy in Patients with Painful Bone Metastases (2021)
Journal Article
Habberstad, R., Frøseth, T. C. S., Aass, N., Bjerkeset, E., Abramova, T., Garcia-Alonso, E., …Klepstad, P. (2021). Clinical Predictors for Analgesic Response to Radiotherapy in Patients with Painful Bone Metastases. Journal of pain and symptom management, 62(4), 681-690. https://doi.org/10.1016/j.jpainsymman.2021.03.022

Background: Radiotherapy (RT) reduces pain in about 60% of patients with painful bone metastases, leaving many patients without clinical benefit. This study assesses predictors for RT effectiveness in patients with painful bone metastases. Materials... Read More about Clinical Predictors for Analgesic Response to Radiotherapy in Patients with Painful Bone Metastases.

Implementing person-centred outcome measures in palliative care: An exploratory qualitative study using Normalisation Process Theory to understand processes and context (2020)
Journal Article
Bradshaw, A., Santarelli, M., Mulderrig, M., Khamis, A., Sartain, K., Boland, J. W., …Murtagh, F. E. (in press). Implementing person-centred outcome measures in palliative care: An exploratory qualitative study using Normalisation Process Theory to understand processes and context. Palliative medicine, https://doi.org/10.1177/0269216320972049

© The Author(s) 2020. Background: Despite evidence demonstrating the utility of using Person-Centred Outcome Measures within palliative care settings, implementing them into routine practice is challenging. Most research has described barriers to, wi... Read More about Implementing person-centred outcome measures in palliative care: An exploratory qualitative study using Normalisation Process Theory to understand processes and context.

Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study (2020)
Journal Article
Baddeley, E., Bravington, A., Johnson, M., Currow, D., Murtagh, F. E., Boland, E., …Boland, J. (2020). Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study. BMJ open, 10(6), Article 039154. https://doi.org/10.1136/bmjopen-2020-039154

INTRODUCTION: Studies regarding the management of malignant bowel obstruction (MBO) report conflicting findings. This is partly due to different outcome measures being used to evaluate severity of MBO and the response to treatments. Furthermore, curr... Read More about Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study.

Patients’ and caregivers’ experiences of driving with chronic breathlessness before and after regular low-dose sustained-release morphine: A qualitative study (2020)
Journal Article
Ferreira, D. H., Boland, J. W., Kochovska, S., Honson, A., Phillips, J. L., & Currow, D. C. (2020). Patients’ and caregivers’ experiences of driving with chronic breathlessness before and after regular low-dose sustained-release morphine: A qualitative study. Palliative medicine, 34(8), 1078-1087. https://doi.org/10.1177/0269216320929549

Background: Chronic breathlessness is a disabling syndrome that profoundly impacts patients’ and caregivers’ lives. Driving is important for most people, including those with advanced disease. Regular, low-dose, sustained-release morphine safely red... Read More about Patients’ and caregivers’ experiences of driving with chronic breathlessness before and after regular low-dose sustained-release morphine: A qualitative study.

Delirium screening practice in specialist palliative care units: A survey (2020)
Journal Article
Woodhouse, R., Siddiqi, N., Boland, J. W., Featherstone, I., & Johnson, M. J. (in press). Delirium screening practice in specialist palliative care units: A survey. BMJ supportive & palliative care, https://doi.org/10.1136/bmjspcare-2020-002251

© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ. Objectives: Delirium is common and distressing in palliative care settings. This survey aims to describe current practice regarding delirium... Read More about Delirium screening practice in specialist palliative care units: A survey.

Development and evaluation of a screening tool to aid the diagnosis of a cluster headache (2020)
Journal Article
Buture, A., Boland, J. W., Dikomitis, L., Huang, C., & Ahmed, F. (2020). Development and evaluation of a screening tool to aid the diagnosis of a cluster headache. Brain Sciences, 10(2), Article 77. https://doi.org/10.3390/brainsci10020077

Cluster headache (CH), a severe primary headache, is often misdiagnosed and mismanaged. The aim of this study was to develop and evaluate a screening tool to aid the diagnosis of CH. We developed a novel 12-item screening tool. This was comprised of... Read More about Development and evaluation of a screening tool to aid the diagnosis of a cluster headache.

Practice review: Evidence-based and effective management of pain in patients with advanced cancer (2020)
Journal Article
Chapman, E. J., Edwards, Z., Boland, J. W., Maddocks, M., Fettes, L., Malia, C., …Bennett, M. I. (2020). Practice review: Evidence-based and effective management of pain in patients with advanced cancer. Palliative medicine, 34(4), 444-453. https://doi.org/10.1177/0269216319896955

© The Author(s) 2020. Background: Pain of a moderate or severe intensity affects over half of patients with advanced cancer and remains undertreated in at least one-third of these patients. Aim: The aim of this study was to provide a pragmatic overvi... Read More about Practice review: Evidence-based and effective management of pain in patients with advanced cancer.

Cannabinoids for adult cancer-related pain: systematic review and meta-analysis (2020)
Journal Article
Boland, E. G., Bennett, M. I., Allgar, V., & Boland, J. W. (2020). Cannabinoids for adult cancer-related pain: systematic review and meta-analysis. BMJ supportive & palliative care, 10(1), 14-24. https://doi.org/10.1136/bmjspcare-2019-002032

Objectives There is increased interest in cannabinoids for cancer pain management and legislative changes are in progress in many countries. This study aims to determine the beneficial and adverse effects of cannabis/cannabinoids compared with plac... Read More about Cannabinoids for adult cancer-related pain: systematic review and meta-analysis.

The relationship between pain, analgesics and survival in patients with advanced cancer: a secondary data analysis of the international European palliative care cancer symptom study. (2019)
Journal Article
Boland, J. W., Allgar, V., Boland, E. G., Bennett, M. I., Kaasa, S., Hjermstad, M. J., & Johnson, M. (2020). The relationship between pain, analgesics and survival in patients with advanced cancer: a secondary data analysis of the international European palliative care cancer symptom study. European Journal of Clinical Pharmacology, 76(3), 393-402. https://doi.org/10.1007/s00228-019-02801-2

© 2019, The Author(s). Purpose: Opioids reduce cancer-related pain but an association with shorter survival is variably reported. Aim: To investigate the relationship between pain, analgesics, cancer and survival within the European Palliative Care C... Read More about The relationship between pain, analgesics and survival in patients with advanced cancer: a secondary data analysis of the international European palliative care cancer symptom study..