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Use of the enhanced frog embryo teratogenesis assay-Xenopus (FETAX) to determine chemically-induced phenotypic effects (2014)
Journal Article
Hu, L., Zhu, J., Rotchell, J. M., Wu, L., Gao, J., & Shi, H. (2015). Use of the enhanced frog embryo teratogenesis assay-Xenopus (FETAX) to determine chemically-induced phenotypic effects. The Science of the total environment, 508, 258-265. https://doi.org/10.1016/j.scitotenv.2014.11.086

The frog embryo teratogenesis assay-Xenopus (FETAX) is an established method for the evaluation of the developmental toxicities of chemicals. To develop an enhanced FETAX that is appropriate for common environmental contaminants, we exposed Xenopus t... Read More

Genetic alterations and cancer formation in a European flatfish at sites of different contamination burdens (2014)
Journal Article
Lerebours, A., Stentiford, G., Bignell, J. P., Lyons, B. P., Derocles, S. A. P., & Rotchell, J. (2014). Genetic alterations and cancer formation in a European flatfish at sites of different contamination burdens. Environmental Science and Technology, 48(17), 10448-10455. https://doi.org/10.1021/es502591p

Fish diseases are an indicator for marine ecosystem health since they provide a biological end-point of historical exposure to stressors. Liver cancer has been used to monitor the effects of exposure to anthropogenic pollution in flatfish for many ye... Read More