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Endo180 modulation by bisphosphonates and diagnostic accuracy in metastatic breast cancer (2012)
Journal Article
Palmieri, C., Caley, M. P., Purshouse, K., Fonseca, A., Rodriguez-Teja, M., Kogianni, G., …Sturge, J. (2013). Endo180 modulation by bisphosphonates and diagnostic accuracy in metastatic breast cancer. The British journal of cancer / Cancer Research Campaign, 108(1), 163-169. https://doi.org/10.1038/bjc.2012.540

Background:Endo180 (CD280; MRC2; uPARAP)-dependent collagen remodelling is dysregulated in primary tumours and bone metastasis. Here, we confirm the release and diagnostic accuracy of soluble Endo180 for diagnosing metastasis in breast cancer (BCa).M... Read More about Endo180 modulation by bisphosphonates and diagnostic accuracy in metastatic breast cancer.

Fluorescence-based experimental model to evaluate the concomitant effect of drugs on the tumour microenvironment and cancer cells (2012)
Journal Article
Ramasamy, K., Khatun, H., Macpherson, L., Caley, M. P., Sturge, J., Mufti, G. J., …Calle, Y. (2012). Fluorescence-based experimental model to evaluate the concomitant effect of drugs on the tumour microenvironment and cancer cells. British journal of haematology, 157(5), 564-579. doi:10.1111/j.1365-2141.2012.09103.x

The response of the tumour microenvironment to anti-cancer drugs can influence treatment efficacy. Current drug-screening methodologies fail to distinguish and quantify simultaneously the concomitant effect of drugs on the tumour stroma and cancer ce... Read More about Fluorescence-based experimental model to evaluate the concomitant effect of drugs on the tumour microenvironment and cancer cells.

Circulating sphingosine-1-phosphate and erythrocyte sphingosine kinase-1 activity as novel biomarkers for early prostate cancer detection (2012)
Journal Article
Nunes, J., Naymark, M., Sauer, L., Muhammad, A., Keun, H., Sturge, J., …Pchejetski, D. (2012). Circulating sphingosine-1-phosphate and erythrocyte sphingosine kinase-1 activity as novel biomarkers for early prostate cancer detection. The British journal of cancer / Cancer Research Campaign, 106(5), (909-915). doi:10.1038/bjc.2012.14. ISSN 0007-0920

Background: Current markers available for screening normal populations and for monitoring prostate cancer (PCa) treatment lack sensitivity and selectivity. Sphingosine-1-phosphate (S1P) is a circulating lipid second messenger involved in cell growth... Read More about Circulating sphingosine-1-phosphate and erythrocyte sphingosine kinase-1 activity as novel biomarkers for early prostate cancer detection.