All Outputs (216)

Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins (2019)
Journal Article
Brittenden, J., Cooper, D., Dimitrova, M., Scotland, G., Cotton, S. C., Elders, A., …Campbell, M. K. (2019). Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins. New England Journal of Medicine, 381(10), 912-922. https://doi.org/10.1056/NEJMoa1805186

Copyright © 2019 Massachusetts Medical Society. BACKGROUND Endovenous laser ablation and ultrasound-guided foam sclerotherapy are recommended alternatives to surgery for the treatment of primary varicose veins, but their long-term comparative effecti... Read More about Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins.

A systematic review of high-intensity interval training as an exercise intervention for intermittent claudication (2019)
Journal Article
Pymer, S., Palmer, J., Harwood, A. E., Ingle, L., Smith, G. E., & Chetter, I. C. (2019). A systematic review of high-intensity interval training as an exercise intervention for intermittent claudication. Journal of vascular surgery, https://doi.org/10.1016/j.jvs.2019.03.050

Background Intermittent claudication (IC) is the most common symptom of peripheral arterial disease, which significantly affects walking ability, functional capacity and quality of life. Supervised exercise programs (SEP) are recommended as first-lin... Read More about A systematic review of high-intensity interval training as an exercise intervention for intermittent claudication.

A pilot feasibility randomised clinical trial comparing dialkylcarbamoylchloride-coated dressings versus standard care for the primary prevention of surgical site infection (2019)
Journal Article
Totty, J. P., Hitchman, L. H., Cai, P. L., Wallace, T., Harwood, A. E., Carradice, D., …Chetter, I. C. (2019). A pilot feasibility randomised clinical trial comparing dialkylcarbamoylchloride-coated dressings versus standard care for the primary prevention of surgical site infection. International wound journal, 16(4), 883-890. https://doi.org/10.1111/iwj.13113

A surgical site infection (SSI) may occur in up to 30% of procedures and results in significant morbidity and mortality. We aimed to assess the feasibility of conducting a randomised controlled trial (RCT) examining the use of dialkylcarbamoylchlorid... Read More about A pilot feasibility randomised clinical trial comparing dialkylcarbamoylchloride-coated dressings versus standard care for the primary prevention of surgical site infection.

Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication (2018)
Journal Article
Harwood, A. E., Totty, J. P., Pymer, S., Huang, C., Hitchman, L., Carradice, D., …Chetter, I. C. (2019). Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication. Journal of vascular surgery, 69(6), 1899-1908.e1. https://doi.org/10.1016/j.jvs.2018.10.065

Objective Intermittent claudication occurs in 20 % of the population over 70 and treatment includes a supervised exercise programme (SEP). Whilst there is evidence demonstrating walking improvements following a SEP there is conflicting data on the ph... Read More about Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication.

Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis (2018)
Journal Article
Pymer, S. A., Tew, G. A., Palmer, J., Ingle, L., Smith, G. E., Chetter, I. C., & Harwood, A. E. (2018). Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis. SAGE Open Medicine, 6, https://doi.org/10.1177/2050312118818295

Background: The aim of this updated review is to consider the evidence base for the effectiveness of home-based exercise programmes as a treatment option for improving walking distance in patients with intermittent claudication. Methods: The Medline,... Read More about Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis.

A Randomized Trial of Early Endovenous Ablation in Venous Ulceration (2018)
Journal Article
Gohel, M. S., Heatley, F., Liu, X., Bradbury, A., Bulbulia, R., Cullum, N., …Davies, A. H. (2018). A Randomized Trial of Early Endovenous Ablation in Venous Ulceration. New England Journal of Medicine, 378(22), 2105-2114. https://doi.org/10.1056/nejmoa1801214

BACKGROUND Venous disease is the most common cause of leg ulceration. Although compression therapy improves venous ulcer healing, it does not treat the underlying causes of venous hypertension. Treatment of superficial venous reflux has been shown t... Read More about A Randomized Trial of Early Endovenous Ablation in Venous Ulceration.

Preferred exercise modalities in patients with intermittent claudication (2018)
Journal Article
Harwood, A., Hitchman, L. H., Ingle, L., Doherty, P., & Chetter, I. C. (2018). Preferred exercise modalities in patients with intermittent claudication. Journal of Vascular Nursing, 36(2), 81-84. https://doi.org/10.1016/j.jvn.2017.12.002

Conventional supervised exercise programs (SEPs) for claudicants are traditionally based on time-constrained, group-based structured programs usually at a hospital site. Uptake of an SEP is poor, despite the high-level evidence demonstrating its clin... Read More about Preferred exercise modalities in patients with intermittent claudication.

“Intermittent claudication a real pain in the calf”—Patient experience of diagnosis and treatment with a supervised exercise program (2017)
Journal Article
Harwood, A., Broadbent, E., Totty, J. P., Smith, G. E., & Chetter, I. C. (2017). “Intermittent claudication a real pain in the calf”—Patient experience of diagnosis and treatment with a supervised exercise program. Journal of Vascular Nursing, 35(3), 131-135. https://doi.org/10.1016/j.jvn.2017.03.001

© 2017 Society for Vascular Nursing, Inc. Intermittent claudication (IC) is a common condition which has severe impacts on quality of life, physical function, and mental health. Supervised exercise is the recommended first-line treatment for patients... Read More about “Intermittent claudication a real pain in the calf”—Patient experience of diagnosis and treatment with a supervised exercise program.

A systematic review of muscle morphology and function in intermittent claudication (2017)
Journal Article
Harwood, A. E., King, S., Totty, J., Smith, G. E., Vanicek, N., & Chetter, I. C. (2017). A systematic review of muscle morphology and function in intermittent claudication. Journal of vascular surgery, 66(4), 1241-1257. https://doi.org/10.1016/j.jvs.2017.05.106

Objective Intermittent claudication (IC) is frequently associated with deterioration in walking capacity and physical function, and it can often result in an impairment in balance. Whereas supervised exercise is recommended by the National Institute... Read More about A systematic review of muscle morphology and function in intermittent claudication.

Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery (2017)
Journal Article
Carradice, D., Chetter, I. C., Totty, J. P., Wallace, T., Bua, N., Pan, D., & Smith, G. E. (2017). Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery. Annals of vascular surgery, 44, 387-392. https://doi.org/10.1016/j.avsg.2017.03.198

© 2017 Elsevier Inc. Background Dressings coated with dialkylcarbamoyl chloride (DACC) are highly hydrophobic and irreversibly bind multiple types of bacteria, trapping them in the dressing and reducing the number of organisms at the wound surface. W... Read More about Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery.

Quality of life in patients with intermittent claudication (2017)
Journal Article
Harwood, A. E., Totty, J. P., Broadbent, E., Smith, G. E., & Chetter, I. C. (2017). Quality of life in patients with intermittent claudication. Gefässchirurgie, 22(3), 159-164. https://doi.org/10.1007/s00772-017-0269-4

© 2017, The Author(s). Background: Intermittent claudication (IC) is a common condition that causes pain in the lower limbs when walking and has been shown to severely impact the quality of life (QoL) of patients. The QoL is therefore often regarded... Read More about Quality of life in patients with intermittent claudication.

Long-term outcomes of a randomized clinical trial of supervised exercise, percutaneous transluminal angioplasty or combined treatment for patients with intermittent claudication due to femoropopliteal disease (2017)
Journal Article
Mazari, F. A., Khan, J. A., Samuel, N., Smith, G., Carradice, D., McCollum, P., & Chetter, I. (2017). Long-term outcomes of a randomized clinical trial of supervised exercise, percutaneous transluminal angioplasty or combined treatment for patients with intermittent claudication due to femoropopliteal disease. Journal of vascular surgery, 65(4), 1239-1240. https://doi.org/10.1016/j.jvs.2017.02.014

Background: To compare the long-term outcomes of angioplasty (PTA), supervised exercise (SEP) and combined treatment (PTA+SEP) in patients with intermittent claudication (IC) due to femoropopliteal disease. Methods: Patients recruited to PTA, SEP and... Read More about Long-term outcomes of a randomized clinical trial of supervised exercise, percutaneous transluminal angioplasty or combined treatment for patients with intermittent claudication due to femoropopliteal disease.

Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial) (2017)
Journal Article
Harwood, A. E., Smith, G. E., Totty, J. P., Carradice, D., Chetter, I. C., Harwood, A., …Smith, G. (2017). Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial). Trials, 18(1), https://doi.org/10.1186/s13063-017-1844-4

© 2017 The Author(s). Background: Peripheral arterial disease (PAD) has a population prevalence of 4.6% with intermittent claudication (IC) presenting as one of the earliest and most common symptoms. PAD has detrimental effects on patients' walking a... Read More about Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial).

Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review (2017)
Journal Article
Totty, J., Bua, N., Smith, G., Harwood, A., Carradice, D., Wallace, T., & Chetter, I. (2017). Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review. Journal of Wound Care, 26(3), 107-114. https://doi.org/10.12968/jowc.2017.26.3.107

Objective: Dialkylcarbomoyl chloride (DACC)-coated dressings (Leukomed Sorbact and Cutimed Sorbact) irreversibly bind bacteria at the wound surface that are then removed when the dressing is changed. They are a recent addition to the wound care profe... Read More about Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review.

A systematic review of management of inadvertent arterial injury during central venous catheterisation (2016)
Journal Article
Dixon, O. G. B., Smith, G. E., Carradice, D., & Chetter, I. C. (2017). A systematic review of management of inadvertent arterial injury during central venous catheterisation. The journal of vascular access, 18(2), 97-102. https://doi.org/10.5301/jva.5000611

© 2017 Wichtig Publishing. Introduction: Central venous catheterisation (CVC) is a technique commonly used to obtain vascular access and over five million CVCs are inserted annually. This systematic review of CVC-related arterial injury aims to compa... Read More about A systematic review of management of inadvertent arterial injury during central venous catheterisation.

Preoperative supervised exercise improves outcomes after elective abdominal aortic aneurysm repair (2016)
Journal Article
Barakat, H. M., Shahin, Y., Khan, J. A., McCollum, P. T., & Chetter, I. C. (2016). Preoperative supervised exercise improves outcomes after elective abdominal aortic aneurysm repair. Annals of Surgery, 264(1), 47-53. https://doi.org/10.1097/SLA.0000000000001609

Objective: The aim of the study was to assess the impact of a preoperative medically supervised exercise program on outcomes after elective abdominal aortic aneurysm (AAA) repair. Background: Functional capacity is an important predictor of postopera... Read More about Preoperative supervised exercise improves outcomes after elective abdominal aortic aneurysm repair.

A Systematic Review of the Uptake and Adherence Rates to Supervised Exercise Programs in Patients with Intermittent Claudication (2016)
Journal Article
Harwood, A., Smith, G. E., Cayton, T., Broadbent, E., & Chetter, I. C. (2016). A Systematic Review of the Uptake and Adherence Rates to Supervised Exercise Programs in Patients with Intermittent Claudication. Annals of vascular surgery, 34, 280-289. https://doi.org/10.1016/j.avsg.2016.02.009

Background Intermittent claudication (IC) is a common and debilitating symptom of peripheral arterial disease and is associated with a significant reduction in a sufferer's quality of life. Guidelines recommend a supervised exercise program (SEP) as... Read More about A Systematic Review of the Uptake and Adherence Rates to Supervised Exercise Programs in Patients with Intermittent Claudication.

Extreme low-lying carotid bifurcations (2016)
Journal Article
Harwood, A. E., Leung, C. C. M., Smith, G. E., & Chetter, I. C. (2016). Extreme low-lying carotid bifurcations. Vascular Medicine, 21(4), 394-395. https://doi.org/10.1177/1358863X15627208

A 52-year-old male with no past medical history was referred to the transient ischaemic attack (TIA) clinic following an event at home. The transient symptoms were of an inability to move his left arm and leg for a period of approximately 15 minutes.... Read More about Extreme low-lying carotid bifurcations.

The Impact of Vein Mechanical Compliance on Arteriovenous Fistula Outcomes (2016)
Journal Article
Smith, G. E., Barnes, R., Chetter, I. C., Barnes, R., & Fagan, M. (2016). The Impact of Vein Mechanical Compliance on Arteriovenous Fistula Outcomes. Annals of vascular surgery, 32, 9-14. https://doi.org/10.1016/j.avsg.2015.11.002

© 2016 Elsevier Inc. Background Arteriovenous fistulae (AVFs) are the preferred access for hemodialysis but suffer a high early failure rate. The aim of this study was to determine how venous distensibility, as measured in vitro, relates to early out... Read More about The Impact of Vein Mechanical Compliance on Arteriovenous Fistula Outcomes.

Infection in prosthetic material (2015)
Journal Article
Smith, G., & Chetter, I. (2015). Infection in prosthetic material. Surgery (Oxford), 33(11), 559-564. https://doi.org/10.1016/j.mpsur.2015.08.003

Surgical site infection (SSI) occurs when a wound created as part of a surgical procedure becomes infected. SSI is one of the most common healthcare-associated infections and occurs in approximately 5% of patients undergoing a surgical procedure. SSI... Read More about Infection in prosthetic material.