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Effects of reducing inspired oxygen concentration for one hour in patients with chronic heart failure: implications for air travel (2013)
Journal Article
Hobkirk, J. P., Damy, T., Walters, M., Bennett, A., Smith, S. J., Ingle, L., …Cleland, J. G. (2013). Effects of reducing inspired oxygen concentration for one hour in patients with chronic heart failure: implications for air travel. European journal of heart failure, 15(5), 505-510. https://doi.org/10.1093/eurjhf/hft003

AimsThe objective of this study was to establish the acute effects of hypoxia on clinical, spirometric, haemodynamic, and echocardiographic variables. Reducing inspired oxygen to 15%, as experienced during commercial air travel, decreases arterial ox... Read More about Effects of reducing inspired oxygen concentration for one hour in patients with chronic heart failure: implications for air travel.

Cardiac output does not limit submaximal exercise capacity in patients with chronic heart failure (2010)
Journal Article
Shelton, R. J., Ingle, L., Rigby, A. S., Witte, K. K., Cleland, J. G., & Clark, A. L. (2010). Cardiac output does not limit submaximal exercise capacity in patients with chronic heart failure. European journal of heart failure, 12(9), 983-989. https://doi.org/10.1093/eurjhf/hfq086

Aims Mechanisms of exercise limitation in patients with chronic heart failure (CHF) are incompletely understood. During matched submaximal, fixed-rate exercise, oxygen uptake is similar in patients and healthy controls. However, the importance of ca... Read More about Cardiac output does not limit submaximal exercise capacity in patients with chronic heart failure.