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All Outputs (133)

Impact of Exercise Training Response on Quality of Life and Cardiovascular Risk Factor Profiles in People with Coronary Artery Disease: Insights from the HIIT or MISS UK trial (2024)
Journal Article
Ingle, L., Powell, R., Begg, B., Birkett, S., Nichols, S., Ennis, S., …McGregor, G. (in press). Impact of Exercise Training Response on Quality of Life and Cardiovascular Risk Factor Profiles in People with Coronary Artery Disease: Insights from the HIIT or MISS UK trial. Archives of physical medicine and rehabilitation, https://doi.org/10.1016/j.apmr.2024.03.002

Objective: To compare the characteristics of “responders” and “non-responders” to 8-weeks of exercise training to determine differences in key cardiovascular disease outcomes in people with coronary artery disease (CAD). Design: Secondary analysis o... Read More about Impact of Exercise Training Response on Quality of Life and Cardiovascular Risk Factor Profiles in People with Coronary Artery Disease: Insights from the HIIT or MISS UK trial.

Inter- and Intra-Observer Reliability and Agreement of O2Pulse Inflection during Cardiopulmonary Exercise Testing: A Comparison of Subjective and Novel Objective Methodology (2024)
Journal Article
Nickolay, T., McGregor, G., Powell, R., Begg, B., Birkett, S., Nichols, S., …Ingle, L. (2024). Inter- and Intra-Observer Reliability and Agreement of O2Pulse Inflection during Cardiopulmonary Exercise Testing: A Comparison of Subjective and Novel Objective Methodology. PLoS ONE, 19(3), Article e0299486. https://doi.org/10.1371/journal.pone.0299486

Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method for evaluating functional capacity, with oxygen pulse (O2Pulse) inflections serving as a potential indicator of myocardial ischaemia. However, the reliability and agreement of iden... Read More about Inter- and Intra-Observer Reliability and Agreement of O2Pulse Inflection during Cardiopulmonary Exercise Testing: A Comparison of Subjective and Novel Objective Methodology.

High INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): a qualitative acceptability study (2024)
Journal Article
Pymer, S., Harwood, A., Ibeggazene, S., McGregor, G., Huang, C., Nicholls, A., …Twiddy, M. (2024). High INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): a qualitative acceptability study. Annals of vascular surgery, 102, Article 17-24. https://doi.org/10.1016/j.avsg.2023.11.043

Introduction A novel high-intensity interval training (HIIT) programme has demonstrated feasibility for patients with intermittent claudication (IC). The aim of this study was to explore patient perspectives of the HIIT programme to inform refinemen... Read More about High INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): a qualitative acceptability study.

High-intensity interval training in patients with intermittent claudication (2023)
Journal Article
Pymer, S., Harwood, A. E., Prosser, J., Waddell, A., Rhavindhran, B., McGregor, G., …Chetter, I. C. (2023). High-intensity interval training in patients with intermittent claudication. Journal of vascular surgery, 78(4), 1048-1056.e4. https://doi.org/10.1016/j.jvs.2023.05.045

Objective: Provision, uptake, adherence, and completion rates for supervised exercise programs (SEP) for intermittent claudication (IC) are low. A shorter, more time-efficient, 6-week, high-intensity interval training (HIIT) program may be an effecti... Read More about High-intensity interval training in patients with intermittent claudication.

A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER) (2023)
Journal Article
Ngaage, D., Mitchell, N., Dean, A., Mitchell, A., Hinde, S., Akowuah, E., …Watson, J. (2023). A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER). Pilot and Feasibility Studies, 9(1), Article 79. https://doi.org/10.1186/s40814-023-01304-3

Objective: To determine the acceptability and feasibility of delivering early outpatient review following cardiac surgery and early cardiac rehabilitation (CR), compared to standard practice to establish if a future large-scale trial is achievable. M... Read More about A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER).

Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study (2023)
Journal Article
James, E., Goodall, S., Nichols, S., Walker, K., Carroll, S., O’Doherty, A. F., & Ingle, L. (2023). Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study. Frontiers in Medicine, 10, Article 1094733. https://doi.org/10.3389/fmed.2023.1094733

Background: Low muscle mass disproportionately affects people with coronary heart disease compared to healthy controls but is under-researched and insufficiently treated. Inflammation, poor nutrition, and neural decline might contribute to low muscle... Read More about Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study.

High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial (2023)
Journal Article
McGregor, G., Powell, R., Begg, B., Birkett, S. T., Nichols, S., Ennis, S., …Shave, R. (2023). High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial. European Journal of Preventive Cardiology, 30(9), 745-755. https://doi.org/10.1093/eurjpc/zwad039

BACKGROUND: There is a lack of international consensus regarding the prescription of high-intensity interval training (HIIT) for people with coronary artery disease (CAD) attending cardiac rehabilitation (CR). AIMS: To assess the clinical effectivene... Read More about High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial.

Effects of exercise prescribed at different levels of claudication pain on walking performance in patients with intermittent claudication: a protocol for a randomised controlled trial (2022)
Journal Article
Birkett, S., Sinclair, J., Seed, S., Pymer, S., Caldow, E., Ingle, L., …Egun, A. (2022). Effects of exercise prescribed at different levels of claudication pain on walking performance in patients with intermittent claudication: a protocol for a randomised controlled trial. Therapeutic Advances in Cardiovascular Disease, 16, https://doi.org/10.1177/17539447221108817

Background: Peripheral artery disease affects over 236 million people globally and the classic symptom is intermittent claudication (IC) which is associated with reduction in physical activity. The evidence that supervised exercise programmes (SEPs)... Read More about Effects of exercise prescribed at different levels of claudication pain on walking performance in patients with intermittent claudication: a protocol for a randomised controlled trial.

Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer (2022)
Journal Article
Ingle, L., Ruilova, S., Cui, Y., DeClercq, V., Sweeney, E., Yu, Z. M., & Forbes, C. C. (2022). Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer. Cancer Causes and Control, https://doi.org/10.1007/s10552-022-01592-9

Purpose: To determine in people with a history of cancer, whether substituting sitting time with other daily activities (i.e., sleeping, walking, moderate and vigorous physical activity) was associated with changes in waist circumference (WC), an imp... Read More about Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer.

Validity and reliability of the movement assessment battery second edition test in children with and without motor impairment: A prospective cohort study (2022)
Journal Article
Ghayour Najafabadi, M., Saghaei, B., Shariat, A., Ingle, L., Babazadeh-Zavieh, S. S., Shojaei, M., & Daneshfar, A. (2022). Validity and reliability of the movement assessment battery second edition test in children with and without motor impairment: A prospective cohort study. Annals of Medicine and Surgery, 77, Article 103672. https://doi.org/10.1016/j.amsu.2022.103672

Background: Examining the reliability and validity of the second edition movement assessment battery test (MABC-2) in children with and without motor impairment. Materials and methods: In this prospective cohort study, the MABC-2 test and development... Read More about Validity and reliability of the movement assessment battery second edition test in children with and without motor impairment: A prospective cohort study.

A pilot study examining the safety and effectiveness of 8-weeks of early cardiac rehabilitation on physical function and psychological well-being in patients following aortic root replacement (2022)
Journal Article
Najafabadi, M., Niazi, S., Mortazavian, S., Khah, A., & Ingle, L. (2022). A pilot study examining the safety and effectiveness of 8-weeks of early cardiac rehabilitation on physical function and psychological well-being in patients following aortic root replacement. Physiotherapy Practice and Research, 43(1), 37-43. https://doi.org/10.3233/PPR-210541

AIM: To determine the effects of a structured, moderate-intensity, early cardiac rehabilitation (CR) program on physical function and psychological wellbeing in patients following aortic root replacement. MATERIALS AND METHODS: Patients were randomly... Read More about A pilot study examining the safety and effectiveness of 8-weeks of early cardiac rehabilitation on physical function and psychological well-being in patients following aortic root replacement.

Effects of aquatic therapy on balance in older adults: a systematic review and meta-analysis (2021)
Journal Article
Shariat, A., Ghayour Najafabadi, M., Ghannadi, S., Nakhostin-Ansari, A., Hakakzadeh, A., Shaw, B. S., …Cleland, J. A. (2021). Effects of aquatic therapy on balance in older adults: a systematic review and meta-analysis. European Geriatric Medicine, https://doi.org/10.1007/s41999-021-00577-2

Purpose: Balance is a key component of movement for daily activities, especially in older adults. Previous studies examining aquatic therapy as an effective way for improving balance have yielded inconsistent findings. The current systematic review a... Read More about Effects of aquatic therapy on balance in older adults: a systematic review and meta-analysis.

Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study (2021)
Journal Article
Nichols, S., Engin, B., Carroll, S., Buckley, J., & Ingle, L. (2021). Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study. Annals of physical and rehabilitation medicine, 64(6), Article 101462. https://doi.org/10.1016/j.rehab.2020.101462

Background: Exercise prescription guidelines for individuals undergoing cardiovascular rehabilitation (CR) are often based on heart rate training zones and rating of perceived exertion (RPE). United Kingdom guidelines indicate that patients should ex... Read More about Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study.

The Rating of Perceived Exertion at the Ventilatory Anaerobic Threshold in Patients with Coronary Heart Disease - Prescribing Implications for Exercise-Based Cardiovascular Rehabilitation: A CARE CR study (2021)
Journal Article
Nichols, S., Engin, B., Carroll, S., Buckley, J., & Ingle, L. (2021). The Rating of Perceived Exertion at the Ventilatory Anaerobic Threshold in Patients with Coronary Heart Disease - Prescribing Implications for Exercise-Based Cardiovascular Rehabilitation: A CARE CR study. Annals of physical and rehabilitation medicine, 64(6), Article 101462. https://doi.org/10.1016/j.rehab.2020.101462

Background: Exercise prescription guidelines for patients undertaking cardiovascular rehabilitation (CR) are based on heart rate training zones and ratings of perceived exertion (RPE). In the UK, guidelines indicate that patients should exercise at a... Read More about The Rating of Perceived Exertion at the Ventilatory Anaerobic Threshold in Patients with Coronary Heart Disease - Prescribing Implications for Exercise-Based Cardiovascular Rehabilitation: A CARE CR study.

A Systematic Review of Exercise Prescription in Patients with Intermittent Claudication: Does Pain Matter? (2021)
Journal Article
Seed, S., Harwood, A., Sinclair, J., Pymer, S., Caldow, E., Ingle, L., …Birkett, S. (in press). A Systematic Review of Exercise Prescription in Patients with Intermittent Claudication: Does Pain Matter?. Annals of vascular surgery, https://doi.org/10.1016/j.avsg.2021.06.025

Background: Current guidelines for intermittent claudication advocate exercise at moderate to maximal claudication pain. However, adherence rates to supervised exercise programmes (SEP) remain poor and claudication pain is a contributing factor. Limi... Read More about A Systematic Review of Exercise Prescription in Patients with Intermittent Claudication: Does Pain Matter?.

The associations between physical activity intensity, cardiorespiratory fitness, and non-alcoholic fatty liver disease (2021)
Journal Article
Kerr, C., Waterworth, S., Brodie, D., Sandercock, G., & Ingle, L. (2021). The associations between physical activity intensity, cardiorespiratory fitness, and non-alcoholic fatty liver disease. Journal of Gastroenterology and Hepatology, 36(12), 3508-3514. https://doi.org/10.1111/jgh.15672

Background and Aim: High levels of physical activity and cardiorespiratory fitness may protect against non-alcoholic fatty liver disease. We investigated whether different physical activity intensities and cardiorespiratory fitness were independent p... Read More about The associations between physical activity intensity, cardiorespiratory fitness, and non-alcoholic fatty liver disease.

Provision of exercise services in patients with peripheral artery disease in the United Kingdom (2021)
Journal Article
Harwood, A. E., Pymer, S., Ibeggazene, S., Ingle, L., Caldow, E., & Birkett, S. T. (in press). Provision of exercise services in patients with peripheral artery disease in the United Kingdom. Vascular, https://doi.org/10.1177/17085381211035259

Objectives: Supervised exercise programmes (SEPs) are a vital treatment for people with intermittent claudication, leading improvements in walking distance and quality of life and are recommended in multiple national and international guidelines. We... Read More about Provision of exercise services in patients with peripheral artery disease in the United Kingdom.

Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers (2021)
Journal Article
Marsden, A. J., Riley, D. R., Birkett, S., Rodriguez-Barucg, Q., Guinn, B. A., Carroll, S., …Beltran-Alvarez, P. (in press). Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers. Amino acids, https://doi.org/10.1007/s00726-021-03024-5

Cardiovascular disease is the major cause of death worldwide. Extensive cardiovascular biomarkers are available using blood tests but very few, if any, investigations have described non-invasive tests for cardiovascular biomarkers based on readily av... Read More about Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers.

Aquatic Therapy for improving Lower Limbs Function in Post-stroke Survivors: A Systematic Review with Meta-Analysis (2021)
Journal Article
Ghayour Najafabadi, M., Shariat, A., Dommerholt, J., Hakakzadeh, A., Nakhostin-Ansari, A., Selk-Ghaffari, M., …Cleland, J. A. (in press). Aquatic Therapy for improving Lower Limbs Function in Post-stroke Survivors: A Systematic Review with Meta-Analysis. Topics in Stroke Rehabilitation, 1-17. https://doi.org/10.1080/10749357.2021.1929011

Background: Lower limb disability is common in chronic stroke patients, and aquatic therapy is one of the modalities used for the rehabilitation of these patients. Objectives: To summarize the evidence of the effects of aquatic therapy on lower limb... Read More about Aquatic Therapy for improving Lower Limbs Function in Post-stroke Survivors: A Systematic Review with Meta-Analysis.