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Derivation and validation of a simple clinical risk-model in heart failure based on 6 minute walk test performance and NT-proBNP status - Do we need specificity for sex and beta-blockers? (2009)
Journal Article
Frankenstein, L., Goode, K., Ingle, L., Remppis, A., Schellberg, D., Nelles, M., …Zugck, C. (2011). Derivation and validation of a simple clinical risk-model in heart failure based on 6 minute walk test performance and NT-proBNP status - Do we need specificity for sex and beta-blockers?. International journal of cardiology, 147(1), 74-78. https://doi.org/10.1016/j.ijcard.2009.08.005

BACKGROUND It is unclear whether risk prediction strategies in chronic heart failure (CHF) need to be specific for sex or beta-blockers. We examined this problem and developed and validated the consequent risk models based on 6-minute-walk-test and N... Read More about Derivation and validation of a simple clinical risk-model in heart failure based on 6 minute walk test performance and NT-proBNP status - Do we need specificity for sex and beta-blockers?.

A review of the six-minute walk test: Its implication as a self-administered assessment tool (2009)
Journal Article
Ingle, L. (2009). A review of the six-minute walk test: Its implication as a self-administered assessment tool. European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology, 8(3), 232-234. https://doi.org/10.1016/j.ejcnurse.2009.01.002

I read with interest the review article by Du and colleagues published in the European Journal of Cardiovascular Nursing in July 2008. The concept that the six-minute walk test (6-MWT) could be adapted as a patient-reported outcome measure of functio... Read More about A review of the six-minute walk test: Its implication as a self-administered assessment tool.

Impact of different diagnostic criteria on the prevalence and prognostic significance of exertional oscillatory ventilation in patients with chronic heart failure (2009)
Journal Article
Ingle, L., Isted, A., Witte, K. K., Cleland, J. G., & Clark, A. L. (2009). Impact of different diagnostic criteria on the prevalence and prognostic significance of exertional oscillatory ventilation in patients with chronic heart failure. European journal of cardiovascular prevention and rehabilitation, 16(4), 451-456. https://doi.org/10.1097/HJR.0b013e32832a4f54

INTRODUCTION: Exertional oscillatory ventilation (EOV) occurs in many patients with chronic heart failure. Two different definitions of EOV have been proposed by Corrá and Leite. We aimed to compare the prevalence of EOV and its prognostic significan... Read More about Impact of different diagnostic criteria on the prevalence and prognostic significance of exertional oscillatory ventilation in patients with chronic heart failure.

An evaluation of a primary and secondary care cardiac rehabilitation service pathway (2009)
Journal Article
Trotman-Beasty, A., McKenna, J., & Ingle, L. (2009). An evaluation of a primary and secondary care cardiac rehabilitation service pathway. British journal of cardiac nursing, 4(4), 178-184

Background: The aim of the study was to assess the synergy between patient treatment pathways in two large primary care trusts (PCTs) and general practices for patients following myocardial infarction (MI) and after completing a 12-week cardiac rehab... Read More about An evaluation of a primary and secondary care cardiac rehabilitation service pathway.

Prognostic Significance of the Double Pressure Reserve in Patients with Chronic Heart Failure (2009)
Journal Article
Ingle, L., & Clark, A. (2009). Prognostic Significance of the Double Pressure Reserve in Patients with Chronic Heart Failure. Open Heart Failure Journal, 2, 1-5. https://doi.org/10.2174/1876535100902010001

Abstract: Introduction: The double pressure reserve (DPR) has recently been shown to have greater prognostic power than metabolic equivalents, heart rate indices, and systolic blood pressure in healthy subjects. It is unclear whether DPR offers any... Read More about Prognostic Significance of the Double Pressure Reserve in Patients with Chronic Heart Failure.

Physical activity readiness in patient withdrawals from cardiac rehabilitation. (2009)
Journal Article
Rivett, M. J., Tsakirides, C., Pringle, A., Carroll, S., Ingle, L., & Dudfield, M. (2009). Physical activity readiness in patient withdrawals from cardiac rehabilitation. British Journal of Nursing, 18(3), 188-191. https://doi.org/10.12968/bjon.2009.18.3.39050

BACKGROUND: Adherence to cardiac rehabilitation (CR) programmes may be an important element for improving and maintaining physical activity (PA) behaviour in secondary prevention. Little is known about the PA behaviour in patients who have withdrawn... Read More about Physical activity readiness in patient withdrawals from cardiac rehabilitation..

Hospital versus community-based phase III cardiac rehabilitation. (2009)
Journal Article
Blake, E., Tsakirides, C., & Ingle, L. (2009). Hospital versus community-based phase III cardiac rehabilitation. British Journal of Nursing, 18(2), 116-122. https://doi.org/10.12968/bjon.2009.18.2.37867

AIM: to compare patient and staff perceptions of phase III cardiac rehabilitation delivered in a hospital versus community setting. METHOD: data were collected by semi-structured interviews with staff and patients. Patients and staff members were int... Read More about Hospital versus community-based phase III cardiac rehabilitation..

The prognostic value of individual NT-proBNP values in chronic heart failure does not change with advancing age (2009)
Journal Article
Frankenstein, L., Clark, A. L., Goode, K., Ingle, L., Remppis, A., Schellberg, D., …Zugck, C. (2009). The prognostic value of individual NT-proBNP values in chronic heart failure does not change with advancing age. Heart, 95(10), 825-829. https://doi.org/10.1136/hrt.2008.158626

Background: It is unclear whether age-related increases in N-terminal pro-brain natriuretic peptide (NT-proBNP) represent a normal physiological process - possibly affecting the prognostic power - of NT-proBNP - or reflect age-related subclinical pat... Read More about The prognostic value of individual NT-proBNP values in chronic heart failure does not change with advancing age.

Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure" (2008)
Journal Article
Ingle, L., Cleland, J. G., & Clark, A. L. (2008). Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure". Heart, 94(6), 748-753. https://doi.org/10.1136/hrt.2007.131144

Background: Epidemiological studies suggest that "diastolic heart failure" (DHF) is common and has a prognosis similar to that of systolic heart failure (SHF). We wanted to assess whether patients with breathlessness who were being treated for DHF ha... Read More about Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure".

Prognostic value and diagnostic potential of cardiopulmonary exercise testing in patients with chronic heart failure (2008)
Journal Article
Ingle, L. (2008). Prognostic value and diagnostic potential of cardiopulmonary exercise testing in patients with chronic heart failure. European journal of heart failure, 10(2), 112-118. https://doi.org/10.1016/j.ejheart.2007.12.011

Cardiopulmonary exercise testing (CPET) is a well established technique for stratifying cardiovascular risk in patients with chronic heart failure (CHF). Important prognostic variables include a reduced peak oxygen uptake which has a central use in c... Read More about Prognostic value and diagnostic potential of cardiopulmonary exercise testing in patients with chronic heart failure.

Combining the ventilatory response to exercise and peak oxygen consumption is no better than peak oxygen consumption alone in predicting mortality in chronic heart failure (2008)
Journal Article
Ingle, L., Witte, K. K., Cleland, J. G. F., & Clark, A. L. (2008). Combining the ventilatory response to exercise and peak oxygen consumption is no better than peak oxygen consumption alone in predicting mortality in chronic heart failure. European journal of heart failure, 10(1), 85-88. https://doi.org/10.1016/j.ejheart.2007.10.010

Background: A low peak oxygen uptake (pV(O2)) and steep V-E/V-CO2 slope are independently associated with a worse prognosis in patients with chronic heart failure (CHF). We wished to confirm whether combining these variables as a ratio would lead to... Read More about Combining the ventilatory response to exercise and peak oxygen consumption is no better than peak oxygen consumption alone in predicting mortality in chronic heart failure.

Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure'' (2007)
Journal Article
Ingle, L., Cleland, J. G. F., & Clark, A. L. (2008). Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure''. Heart, 94(6), 748-753. https://doi.org/10.1136/hrt.2007.131144

Background: Epidemiological studies suggest that "diastolic heart failure'' (DHF) is common and has a prognosis similar to that of systolic heart failure (SHF). We wanted to assess whether patients with breathlessness who were being treated for DHF h... Read More about Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure''.

Value of the 6-minute walk test in older patients with chronic heart failure (2007)
Journal Article
Ingle, L. (2007). Value of the 6-minute walk test in older patients with chronic heart failure. Cardiology in review, 24(10), 29-32

We assessed the prognostic value of the 6-minute walk test (6-MWT) among 1592 subjects with differing degrees of left ventricular systolic dysfunction (LVSD). We found that the 6-MWT was an independent predictor of mortality, particularly among patie... Read More about Value of the 6-minute walk test in older patients with chronic heart failure.

The prognostic value of cardiopulmonary exercise testing with a peak respiratory exchange ratio of < 1.0 in patients with chronic heart failure (2007)
Journal Article
Ingle, L., Witte, K. K., Cleland, J. G., & Clark, A. L. (2008). The prognostic value of cardiopulmonary exercise testing with a peak respiratory exchange ratio of < 1.0 in patients with chronic heart failure. International journal of cardiology, 127(1), 88-92. https://doi.org/10.1016/j.ijcard.2007.04.075

Background: Peak oxygen consumption derived from a maximal cardiopulmonary exercise test (CPET) is a standard prognostic indicator in patients with chronic heart failure (CHF). Tests with a peak respiratory exchange ratio (pRER) < 1.0 are often tak... Read More about The prognostic value of cardiopulmonary exercise testing with a peak respiratory exchange ratio of < 1.0 in patients with chronic heart failure.

Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy (2007)
Journal Article
Ingle, L., Rigby, A. S., Carroll, S., Butterly, R., King, R. F., Cooke, C. B., …Clark, A. L. (2007). Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy. Experimental and Clinical Cardiology, 12(1), 46-47

Background: Increasing body mass index, cholesterol and body fat are associated with a better prognosis in patients with left ventricular systolic dysfunction (LVSD). Beta-blocker usage is associated with changes in body composition and increased bod... Read More about Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy.

Cardiorespiratory requirements of the 6-min walk test in older patients with left ventricular systolic dysfunction and no major structural heart disease (2007)
Journal Article
Ingle, L., Wilkinson, M., Carroll, S., Boyes, C., Butterly, R., King, R., …Clark, A. (2007). Cardiorespiratory requirements of the 6-min walk test in older patients with left ventricular systolic dysfunction and no major structural heart disease. International journal of sports medicine, 28(8), 678-684. https://doi.org/10.1055/s-2007-964886

The six-minute walk test (6-MWT) is widely used to assess functional status in patients with chronic heart failure (CHF). The aims of the present study were: (1) to compare metabolic gas exchange during the 6-MWT in older patients with left ventricul... Read More about Cardiorespiratory requirements of the 6-min walk test in older patients with left ventricular systolic dysfunction and no major structural heart disease.

Theoretical rationale and practical recommendations for cardiopulmonary exercise testing in patients with chronic heart failure (2007)
Journal Article
Ingle, L. (2007). Theoretical rationale and practical recommendations for cardiopulmonary exercise testing in patients with chronic heart failure. Heart Failure Reviews, 12(1), 12-22. https://doi.org/10.1007/s10741-007-9000-y

The syndrome of chronic heart failure (CHF) becomes increasingly prevalent in older patients, and while mortality rates are declining in most cardiovascular diseases, both prevalence and mortality in CHF remain high. The heart is unable to meet the d... Read More about Theoretical rationale and practical recommendations for cardiopulmonary exercise testing in patients with chronic heart failure.

Prognostic value of the 6 min walk test and self-perceived symptom severity in older patients with chronic heart failure (2007)
Journal Article
Ingle, L., Rigby, A. S., Carroll, S., Butterly, R., King, R. F., Cooke, C. B., …Clark, A. L. (2007). Prognostic value of the 6 min walk test and self-perceived symptom severity in older patients with chronic heart failure. European Heart Journal, 28(5), 560-568. https://doi.org/10.1093/eurheartj/ehl527

Background: The 6 min walk test (6-MWT) is a simple and popular test for evaluating functional status in patients with chronic heart failure (CHF). However, the prognostic value of the 6-MWT in a large, representative sample of CHF patients, and in p... Read More about Prognostic value of the 6 min walk test and self-perceived symptom severity in older patients with chronic heart failure.

Efficacy of lifestyle intervention on peak exercise cardiac power output and reserve in premenopausal obese females: A randomised pilot study (2007)
Journal Article
Carroll, S., Marshall, P., Borkoles, E., Ingle, L., Barker, D., & Tan, L. B. (2007). Efficacy of lifestyle intervention on peak exercise cardiac power output and reserve in premenopausal obese females: A randomised pilot study. International journal of cardiology, 119(2), 147-155. https://doi.org/10.1016/j.ijcard.2006.07.099

Background: Clinically obese women have a two-fold increased risk for the development of heart failure. Among younger premenopausal females, obesity has been associated with cardiac remodelling and impaired resting systolic and diastolic function. Ho... Read More about Efficacy of lifestyle intervention on peak exercise cardiac power output and reserve in premenopausal obese females: A randomised pilot study.