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Validity of telemetric-derived measures of heart rate variability: a systematic review (2016)
Journal Article
Board, E., Ispoglou, T., & Ingle, L. (2016). Validity of telemetric-derived measures of heart rate variability: a systematic review. Journal of exercise physiology online / American Society of Exercise Physiologists, 19(6), 64-84

Heart rate variability (HRV) is a widely accepted indirect measure of autonomic function with widespread application across many settings. Although traditionally measured from the ‘gold standard’ criterion electrocardiography (ECG), the development o... Read More

Characterization of the metabolically healthy phenotype in overweight and obese British men (2016)
Journal Article
Ingle, L., Swainson, M., Brodie, D., & Sandercock, G. R. (2017). Characterization of the metabolically healthy phenotype in overweight and obese British men. Preventive Medicine, 94, 7-11. https://doi.org/10.1016/j.ypmed.2016.11.001

We calculated the prevalence of the metabolically healthy but obese (MHO) phenotype in (n=9 177) British men (age 48.9±7.4 years) attending preventive health screening between 2000 and 2009. We examined differences in cardiorespiratory fitness (Fitne... Read More

High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation (2016)
Journal Article
McGregor, G., Nichols, S., Hamborg, T., Bryning, L., Tudor-Edwards, R., Markland, D., …Backx, K. (2016). High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation. BMJ open, 6(11), e012843. https://doi.org/10.1136/bmjopen-2016-012843

Introduction: Current international guidelines for cardiac rehabilitation (CR) advocate moderate-intensity exercise training (MISS, moderate-intensity steady state). This recommendation predates significant advances in medical therapy for coronary he... Read More

Associations between cardiorespiratory fitness and the metabolic syndrome in British men (2016)
Journal Article
Ingle, L., Mellis, M., Brodie, D., & Sandercock, G. R. (2017). Associations between cardiorespiratory fitness and the metabolic syndrome in British men. Heart, 103(7), 524-528. https://doi.org/10.1136/heartjnl-2016-310142

Background: Age and body mass index (BMI) are positively associated with the development of the metabolic syndrome (MetS). Cardiorespiratory fitness (CRF) can attenuate BMI-related increases in prevalence of MetS, but the nature of this association a... Read More

The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise (2016)
Journal Article
O’Doherty, A. F., Sathyapalan, T., Rigby, A. S., Ingle, L., & Carroll, S. (2018). The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise. European Journal of Nutrition, 57(1), 309-318. https://doi.org/10.1007/s00394-016-1320-z

© 2016 The Author(s) Purpose: The Oral Fat Tolerance Test (OFTT) is regarded as a repeatable measure used to assess postprandial triglyceride (TAG) levels, with higher levels observed in cardio-metabolic disorders. Acute aerobic exercise intervention... Read More

Effects of exercise-based cardiac rehabilitation on cardiorespiratory fitness: A meta-analysis of UK studies (2016)
Journal Article
Ingle, L., Almodhy, M., & Sandercock, G. R. (2016). Effects of exercise-based cardiac rehabilitation on cardiorespiratory fitness: A meta-analysis of UK studies. International journal of cardiology, 221, 644-651. https://doi.org/10.1016/j.ijcard.2016.06.101

Background: Exercise-based cardiac rehabilitation can promote meaningful improvements in cardiorespiratory fitness (fitness) but the magnitude of such improvements varies according to local characteristics of exercise programmes. We aimed to determin... Read More

Submaximal fitness and mortality risk reduction in coronary heart disease: A retrospective cohort study of community-based exercise rehabilitation (2016)
Journal Article
Taylor, C., Tsakirides, C., Moxon, J., Moxon, J. W., Dudfield, M., Witte, K. K., …Carroll, S. (2016). Submaximal fitness and mortality risk reduction in coronary heart disease: A retrospective cohort study of community-based exercise rehabilitation. BMJ open, 6(6), https://doi.org/10.1136/bmjopen-2016-011125

Objectives To examine the association between submaximal cardiorespiratory fitness (sCRF) and all-cause mortality in a cardiac rehabilitation (CR) cohort. Design Retrospective cohort study of participants entering CR between 26 May 1993 and 16 Octob... Read More

Physical activity profiles and selected muscular fitness variables in English schoolchildren: A north–south divide? (2016)
Journal Article
Ingle, L., Stephenson, A., & Sandercock, G. R. (2016). Physical activity profiles and selected muscular fitness variables in English schoolchildren: A north–south divide?. European journal of sport science : the official journal of the European College of Sport Science, 16(8), 1187-1196. https://doi.org/10.1080/17461391.2016.1183714

Introduction: The aim of the study was to compare and contrast habitual physical activity profiles and muscular fitness in schoolchildren from northern and southern regions of England. Methods: Data were collected from two secondary schools in the No... Read More

A clinician's guide to cardiopulmonary exercise testing 2: test interpretation (2015)
Journal Article
Nichols, S., Taylor, C., & Ingle, L. (2015). A clinician's guide to cardiopulmonary exercise testing 2: test interpretation. British journal of hospital medicine, 76(5), 281-289. https://doi.org/10.12968/hmed.2015.76.5.281

Data obtained from cardiopulmonary exercise testing offer additional interpretive power over conventional exercise tolerance testing. When used correctly, these data allow improved clinical decision making in patients with cardiometabolic and respira... Read More

A clinician's guide to cardiopulmonary exercise testing 1: An introduction (2015)
Journal Article
Nichols, S., Taylor, C., & Ingle, L. (2015). A clinician's guide to cardiopulmonary exercise testing 1: An introduction. British journal of hospital medicine, 76(4), 192-195. https://doi.org/10.12968/hmed.2015.76.4.192

Compared to standard exercise tolerance testing, cardiopulmonary exercise testing is a reliable and powerful tool that can be used for risk stratification, exercise prescription and clinical diagnosis.

Impact of exercise-induced bronchoconstriction on athletic performance and airway health in rugby union players (2014)
Journal Article
Ingle, L., Greenwell, J., & Spiteri, D. B. (2014). Impact of exercise-induced bronchoconstriction on athletic performance and airway health in rugby union players. International sportmed journal for FIMS ISMJ, 15(4), 333-342

Background: There is emerging evidence that the prevalence of exercise-induced bronchospasm (EIB) is significantly under-reported in many sports. There is little known about the potential performance improvement that may exist when sports players are... Read More

Cardiometabolic health benefits of a six-week high-intensity interval training intervention : a case study (2014)
Journal Article
Siddall-Gleadall, D., Gritt, J., Burke, R., O'Carroll, G., Bray, J., Ingle, L., & Garrett, A. (2014). Cardiometabolic health benefits of a six-week high-intensity interval training intervention : a case study. Journal of sports sciences, 32(Supplement 2), s28-s32. doi:10.1080/02640414.2014.968381

Regular physical activity is recommended for patients diagnosed with impaired glucose tolerance (IGT) and Type 2 Diabetes. However, "lack of time" is a common cited barrier in achieving the recommended weekly physical activity guidelines. High-intens... Read More

Cardiopulmonary exercise testing: an overview (2014)
Journal Article
McGregor, G., & Ingle, L. (2014). Cardiopulmonary exercise testing: an overview. British journal of cardiac nursing, 9(11), 541-543. https://doi.org/10.12968/bjca.2014.9.11.541

A cardiopulmonary exercise test (CPEX or CPET) is an exercise tolerance test which combines the standard measures of electrocardiography (ECG) and blood pressure with ventilatory gas exchange data. Despite having been available for many years, CPEX h... Read More

Effectiveness of a six-week high-intensity interval training programme on cardiometabolic markers in sedentary males (2014)
Conference Proceeding
Gleadall-Siddall, D., Burke, R., Gritt, J., O'Carroll, G., Bray, J., Ingle, L., & Garrett, A. (2014). Effectiveness of a six-week high-intensity interval training programme on cardiometabolic markers in sedentary males. doi:10.1080/02640414.2014.968390

High-intensity interval training (HIT) has been proposed as an effective, time efficient strategy to elicit similar cardiometabolic health benefits as traditional moderate-intensity endurance training. This is an important consideration as "lack of t... Read More

Variability of automated carotid intima-media thickness measurements by novice operators (2014)
Journal Article
Nichols, S., Milner, M., Meijer, R., Carroll, S., & Ingle, L. (2016). Variability of automated carotid intima-media thickness measurements by novice operators. Clinical physiology and functional imaging, 36(1), 25-32. https://doi.org/10.1111/cpf.12189

Carotid intima-media thickness (C-IMT) measurements provide a non-invasive assessment of sub-clinical atherosclerosis. The aim of the study was to assess the inter- and intra-observer variability of automated C-IMT measurements undertaken by two novi... Read More

The relation between repeated 6-minute walk test performance and outcome in patients with chronic heart failure (2014)
Journal Article
Ingle, L., Cleland, J. G., & Clark, A. L. (2014). The relation between repeated 6-minute walk test performance and outcome in patients with chronic heart failure. Annals of physical and rehabilitation medicine, 57(4), 244-253. https://doi.org/10.1016/j.rehab.2014.03.004

Objective: To assess the prognostic implications of the 6-minute walk test (6-MWT) distance measured twice, one year apart, in a large sample of patients with chronic heart failure (CHF) followed for an extended period ( > . 8. years from baseline).... Read More

The long-term prognostic significance of 6-minute walk test distance in patients with chronic heart failure (2014)
Journal Article
Ingle, L., Cleland, J. G., & Clark, A. L. (2014). The long-term prognostic significance of 6-minute walk test distance in patients with chronic heart failure. Biomed research international, 2014, 1-7. https://doi.org/10.1155/2014/505969

Background. The 6-minute walk test (6-MWT) is used to assess patients with chronic heart failure (CHF). The prognostic significance of the 6-MWT distance during long-term followup ( > 5 years) is unclear. Methods. 1,667 patients (median [inter-quarti... Read More

Development of a composite model derived from cardiopulmonary exercise tests to predict mortality risk in patients with mild-to-moderate heart failure (2014)
Journal Article
Ingle, L., Rigby, A. S., Sloan, R., Carroll, S., Goode, K. M., Cleland, J. G., & Clark, A. L. (2014). Development of a composite model derived from cardiopulmonary exercise tests to predict mortality risk in patients with mild-to-moderate heart failure. Heart, 100(10), 781-786. https://doi.org/10.1136/heartjnl-2013-304614

Objective: Cardiopulmonary exercise testing (CPET) is used to predict outcome in patients with mild-to-moderate heart failure (HF). Single CPET-derived variables are often used, but we wanted to see if a composite score achieved better predictive pow... Read More

The variability of high intensity exercise tests in pre-pubertal boys (2013)
Journal Article
Ingle, L., & Tolfrey, K. (2013). The variability of high intensity exercise tests in pre-pubertal boys. International journal of sports medicine, 34(12), 1063-1069. https://doi.org/10.1055/s-0032-1327714

The aim of the study was to determine the variability of different performance tests during high intensity exercise in active, untrained pre- and early pubertal boys. Participants were habituated to the Wingate anaerobic test (WAnT), force-velocity t... Read More