Skip to main content

Research Repository

Advanced Search

All Outputs (2)

Differential induction of cellular proliferation, hypertrophy and apoptosis in H9c2 cardiomyocytes by exogenous tissue factor (2010)
Journal Article
Alkistis Frentzou, G., Collier, M. E. W., Ettelaie, C., & Seymour, A. L. (2010). Differential induction of cellular proliferation, hypertrophy and apoptosis in H9c2 cardiomyocytes by exogenous tissue factor. Molecular and Cellular Biochemistry, 345(1-2), 119-130. https://doi.org/10.1007/s11010-010-0565-8

Recent evidence has shown that prolonged exposure to exogenous tissue factor (TF) can alter the cellular functions of cardiomyocytes resulting in cardiac dysfunction. The effect of TF may arise from local inflammation within or in the vicinity of the... Read More about Differential induction of cellular proliferation, hypertrophy and apoptosis in H9c2 cardiomyocytes by exogenous tissue factor.

Induction of endothelial cell proliferation by recombinant and microparticle-tissue factor involves β1-integrin and extracellular signal regulated kinase activation (2010)
Journal Article
Collier, M. E. W., & Ettelaie, C. (2010). Induction of endothelial cell proliferation by recombinant and microparticle-tissue factor involves β1-integrin and extracellular signal regulated kinase activation. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(9), 1810-1817. https://doi.org/10.1161/ATVBAHA.110.211854

Objective: Increased levels of circulating tissue factor (TF) in the form of microparticles increase the risk of thrombosis. However, any direct influence of microparticle-associated TF on vascular endothelial cell proliferation is not known. In this... Read More about Induction of endothelial cell proliferation by recombinant and microparticle-tissue factor involves β1-integrin and extracellular signal regulated kinase activation.