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All Outputs (10)

Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease (2014)
Journal Article
Ji, B., Genever, P. G., Patton, R. J., & Fagan, M. J. (2014). Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease. International journal for numerical methods in biomedical engineering, 30(11), 1085-1102. https://doi.org/10.1002/cnm.2645

Multiple myeloma (MM) is the second most common haematological malignancy and results in destructive bone lesions. The interaction between MM cells and the bone microenvironment plays an important role in the development of the tumour cells and MM-in... Read More about Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease.

A predator-prey based mathematical model of the bone remodelling cycle: Exploring the relationship between the model parameters and biochemical factors (2014)
Journal Article
Ji, B., Yang, Q., Genever, P. G., Patton, R. J., & Fagan, M. J. (2014). A predator-prey based mathematical model of the bone remodelling cycle: Exploring the relationship between the model parameters and biochemical factors. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 228(10), 1035-1042. https://doi.org/10.1177/0954411914554633

© IMechE 2014. Bone remodelling is a vital process which enables bone to repair, renew and optimize itself. Disorders in the bone remodelling process are inevitably manifested in bone-related diseases, such as hypothyroidism, primary hyperparathyroid... Read More about A predator-prey based mathematical model of the bone remodelling cycle: Exploring the relationship between the model parameters and biochemical factors.

The effect of osteocyte apoptosis on signalling in the osteocyte and bone lining cell network: A computer simulation (2012)
Journal Article
Jahani, M., Genever, P. G., Patton, R. J., Ahwal, F., & Fagan, M. J. (2012). The effect of osteocyte apoptosis on signalling in the osteocyte and bone lining cell network: A computer simulation. Journal of biomechanics, 45(16), 2876-2883. https://doi.org/10.1016/j.jbiomech.2012.08.005

Osteocytes play a critical role in the regulation of bone remodelling by translating strain due to mechanical loading into biochemical signals transmitted through the interconnecting lacuno-canalicular network to bone lining cells (BLCs) on the bone... Read More about The effect of osteocyte apoptosis on signalling in the osteocyte and bone lining cell network: A computer simulation.

Small-vocabulary speech recognition using a silent speech interface based on magnetic sensing (2012)
Journal Article
Hofe, R., Ell, S. R., Fagan, M. J., Gilbert, J., Green, P. D., Moore, R. K., & Rybchenko, S. (2013). Small-vocabulary speech recognition using a silent speech interface based on magnetic sensing. Speech communication, 55(1), 22-32. https://doi.org/10.1016/j.specom.2012.02.001

This paper reports on word recognition experiments using a silent speech interface based on magnetic sensing of articulator movements. A magnetic field was generated by permanent magnet pellets fixed to relevant speech articulators. Magnetic field se... Read More about Small-vocabulary speech recognition using a silent speech interface based on magnetic sensing.

A novel mathematical model of bone remodelling cycles for trabecular bone at the cellular level (2012)
Journal Article
Ji, B., Genever, P. G., Patton, R. J., Putra, D., & Fagan, M. J. (2012). A novel mathematical model of bone remodelling cycles for trabecular bone at the cellular level. Biomechanics and Modeling in Mechanobiology, 11(7), 973-982. https://doi.org/10.1007/s10237-011-0366-3

After an initial phase of growth and development, bone undergoes a continuous cycle of repair, renewal and optimisation by a process called remodelling. This paper describes a novel mathematical model of the trabecular bone remodelling cycle. It is e... Read More about A novel mathematical model of bone remodelling cycles for trabecular bone at the cellular level.

Speech synthesis parameter generation for the assistive silent speech interface MVOCA (2011)
Journal Article
Hofe, R., Ell, S. R., Fagan, M. J., Gilbert, J. M., Green, P. D., Moore, R. K., & Rybchenko, S. I. (2011). Speech synthesis parameter generation for the assistive silent speech interface MVOCA

In previous publications, a silent speech interface based on permanent-magnetic articulography (PMA) has been introduced and evaluated using standard automatic speech recognition techniques. However, word recognition is a task that is computationally... Read More about Speech synthesis parameter generation for the assistive silent speech interface MVOCA.

Isolated word recognition of silent speech using magnetic implants and sensors (2010)
Journal Article
Gilbert, J. M., Rybchenko, S. I., Hofe, R., Ell, S. R., Fagan, M. J., Moore, R. K., & Green, P. (2010). Isolated word recognition of silent speech using magnetic implants and sensors. Medical engineering & physics, 32(10), 1189-1197. https://doi.org/10.1016/j.medengphy.2010.08.011

There are a number of situations where individuals wish to communicate verbally but are unable to use conventional means so called 'silent speech'. These include speakers in noisy and covert situations as well as patients who have lost their voice as... Read More about Isolated word recognition of silent speech using magnetic implants and sensors.

Accurate quantification of the influence of benthic macro- and meio-fauna on the geometric properties of estuarine muds by micro computer tomography (2007)
Journal Article
Mazik, K., Curtis, N., Fagan, M. J., Taft, S., & Elliott, M. (2008). Accurate quantification of the influence of benthic macro- and meio-fauna on the geometric properties of estuarine muds by micro computer tomography. Journal of experimental marine biology and ecology, 354(2), 192-201. https://doi.org/10.1016/j.jembe.2007.11.006

This paper describes the novel application of high resolution micro computer tomography (microCT) to the quantification of the properties of marine biogenic structures. CT scanning has been used to examine sediments in the past but the resolution of... Read More about Accurate quantification of the influence of benthic macro- and meio-fauna on the geometric properties of estuarine muds by micro computer tomography.

Development of a (silent) speech recognition system for patients following laryngectomy (2007)
Journal Article
Fagan, M. J., Ell, S. R., Gilbert, J. M., Sarrazin, E., & Chapman, P. M. (2008). Development of a (silent) speech recognition system for patients following laryngectomy. Medical engineering & physics, 30(4), 419-425. https://doi.org/10.1016/j.medengphy.2007.05.003

Surgical voice restoration post-laryngectomy has a number of limitations and drawbacks. The present gold standard involves the use of a tracheo-oesophageal fistula (TOF) valve to divert air from the lungs into the throat, which vibrates, and from thi... Read More about Development of a (silent) speech recognition system for patients following laryngectomy.