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Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands (2015)
Journal Article
Alshehri, O. M., Montague, S., Watson, S., Carter, P., Sarker, N., Manne, B. K., …Watson, S. P. (2015). Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands. Biochemical Journal, 468(3), 459-473. https://doi.org/10.1042/BJ20150192

Platelets are activated by a range of stimuli that share little or no resemblance in structure to each other or to recognized ligands, including diesel exhaust particles (DEP), small peptides [4N1-1, Champs (computed helical anti-membrane proteins),... Read More about Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands.

Human platelet IgG Fc receptor FcγRIIA in immunity and thrombosis (2015)
Journal Article
Arman, M., & Krauel, K. (2015). Human platelet IgG Fc receptor FcγRIIA in immunity and thrombosis. Journal of thrombosis and haemostasis : JTH, 13(6), 893-908. https://doi.org/10.1111/jth.12905

© 2015 International Society on Thrombosis and Haemostasis. Beyond their prominent role in hemostasis and thrombosis, platelets are increasingly recognized as having immunologic functions. Supporting this, human platelets express FcγRIIA (CD32a), a l... Read More about Human platelet IgG Fc receptor FcγRIIA in immunity and thrombosis.