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Visualization of diffusion limited antimicrobial peptide attack on supported lipid membranes (2018)
Journal Article
Heath, G. R., Harrison, P. L., Strong, P. N., Evans, S. D., & Miller, K. (2018). Visualization of diffusion limited antimicrobial peptide attack on supported lipid membranes. Soft matter, 14(29), 6146-6154. https://doi.org/10.1039/c8sm00707a

Understanding the mechanism of action of antimicrobial peptides (AMP) is fundamental to the development and design of peptide based antimicrobials. Utilizing fast-scan atomic force microscopy (AFM) we detail the attack of an AMP on both prototypical... Read More

Phospholipid dependent mechanism of smp24, an α-helical antimicrobial peptide from scorpion venom (2016)
Journal Article
Harrison, P. L., Heath, G. R., Johnson, B. R., Abdel-Rahman, M. A., Strong, P. N., Evans, S. D., & Miller, K. (2016). Phospholipid dependent mechanism of smp24, an α-helical antimicrobial peptide from scorpion venom. BBA - Biomembranes, 1858(11), 2737-2744. https://doi.org/10.1016/j.bbamem.2016.07.018

Determining the mechanism of action of antimicrobial peptides (AMPs) is critical if they are to be developed into the clinical setting. In recent years high resolution techniques such as atomic force microscopy (AFM) have increasingly been utilised t... Read More