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Microfluidic synthesis of silica nanoparticles using polyethylenimine polymers (2010)
Journal Article
He, P., Greenway, G., & Haswell, S. J. (2011). Microfluidic synthesis of silica nanoparticles using polyethylenimine polymers. Chemical Engineering Journal, 167(2-3), (694-699). doi:10.1016/j.cej.2010.08.079. ISSN 1385-8947

A microfluidic reactor system for the synthesis of silica nanoparticles has been developed from commercially available ETFE tubing (0.17-1.0 mm diameter) connected in series to support the hydrolysis, nucleation and particle growth based on a sol-gel... Read More

Permeability of silica monoliths containing micro- and nano-pores (2010)
Journal Article
Mansfield, A., Fletcher, P. D. I., Haswell, S. J., He, P., & Kelly, S. M. (2011). Permeability of silica monoliths containing micro- and nano-pores. Journal of Porous Materials, 18(4), 501-508. doi:10.1007/s10934-010-9403-3

For applications as catalyst supports in flow reactors, porous silica monoliths require a combination of connected pores of micron-scale to enable fluid flow plus nm-scale pores to enable high catalyst area and activity. We have synthesised a range p... Read More

Development of a monolith based immobilized lipase micro-reactor for biocatalytic reactions in a biphasic mobile system (2009)
Journal Article
He, P., Greenway, G., & Haswell, S. J. (2010). Development of a monolith based immobilized lipase micro-reactor for biocatalytic reactions in a biphasic mobile system. Process Biochemistry, 45(4), (593-597). doi:10.1016/j.procbio.2009.12.008. ISSN 1359-5113

This paper reports a simple method for producing macroporous silica-monoliths with controllable porosity that can be used for the immobilization of lipases to generate an active and stable micro-reactor for biocatalysis. A range of commercially avail... Read More

The on-line synthesis of enzyme functionalized silica nanoparticles in a microfluidic reactor using polyethylenimine polymer and R5 peptide (2008)
Journal Article
He, P., Greenway, G., & Haswell, S. J. (2008). The on-line synthesis of enzyme functionalized silica nanoparticles in a microfluidic reactor using polyethylenimine polymer and R5 peptide. Nanotechnology, 19(31), 315603. doi:10.1088/0957-4484/19/31/315603

A simple microfluidic reactor system is described for the effective synthesis of enzyme functionalized nanoparticles which offers many advantages over batch reactions, including excellent enzyme efficiencies. Better control of the process parameters... Read More