Skip to main content

Research Repository

Advanced Search

All Outputs (33)

Coagulation Profiles in Humans Exposed to Exertional Hypobaric Decompression Stress Determined by Calibrated Automated Thrombogram (2023)
Journal Article
Madden, L. A., Vince, R. V., Edwards, V. C., Lee, V. M., & Connolly, D. M. (2023). Coagulation Profiles in Humans Exposed to Exertional Hypobaric Decompression Stress Determined by Calibrated Automated Thrombogram. Hemato, 4(4), 301-310. https://doi.org/10.3390/hemato4040024

The blood coagulation response to decompression stress in humans has yet to be fully investigated. Here we utilised calibrated automated thrombogram (CAT) on samples from healthy volunteers exposed to decompression stress to investigate real-time thr... Read More about Coagulation Profiles in Humans Exposed to Exertional Hypobaric Decompression Stress Determined by Calibrated Automated Thrombogram.

Feasibility of delivering supervised exercise training following surgical resection and during adjuvant chemotherapy for pancreatic ductal adenocarcinoma (PRECISE): a case series (2023)
Journal Article
Brown, M., O’Connor, D., Turkington, R., Eatock, M., Vince, R., Hulme, C., …Prue, G. (2023). Feasibility of delivering supervised exercise training following surgical resection and during adjuvant chemotherapy for pancreatic ductal adenocarcinoma (PRECISE): a case series. BMC Sports Science, Medicine and Rehabilitation, 15(1), Article 116. https://doi.org/10.1186/s13102-023-00722-3

Introduction: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive neoplasm, with surgical resection and adjuvant chemotherapy the only curative treatment. Treatment-related toxicities place a considerable burden on patients although exercise tra... Read More about Feasibility of delivering supervised exercise training following surgical resection and during adjuvant chemotherapy for pancreatic ductal adenocarcinoma (PRECISE): a case series.

The Effect of a Very-Low-Calorie Diet (VLCD) vs. a Moderate Energy Deficit Diet in Obese Women with Polycystic Ovary Syndrome (PCOS)—A Randomised Controlled Trial (2023)
Journal Article
Deshmukh, H., Papageorgiou, M., Wells, L., Akbar, S., Strudwick, T., Deshmukh, K., …Sathyapalan, T. (2023). The Effect of a Very-Low-Calorie Diet (VLCD) vs. a Moderate Energy Deficit Diet in Obese Women with Polycystic Ovary Syndrome (PCOS)—A Randomised Controlled Trial. Nutrients, 15(18), Article 3872. https://doi.org/10.3390/nu15183872

We performed an open-label, randomised controlled trial to compare the effects of a very-low-calorie diet (VLCD) vs. moderate energy deficit approach on body weight, body composition, free androgen index (FAI), and metabolic markers in obese women wi... Read More about The Effect of a Very-Low-Calorie Diet (VLCD) vs. a Moderate Energy Deficit Diet in Obese Women with Polycystic Ovary Syndrome (PCOS)—A Randomised Controlled Trial.

Digital Health Solutions for Weight Loss and Obesity: A Narrative Review (2023)
Journal Article
Irvin, L., Madden, L. A., Marshall, P., & Vince, R. V. (2023). Digital Health Solutions for Weight Loss and Obesity: A Narrative Review. Nutrients, 15(8), Article 1858. https://doi.org/10.3390/nu15081858

Personal exercise programmes have long been used and prescribed for weight loss and the improvement of quality of life in obese patients. While individualised programmes are usually the preferred option, they can be more costly and challenging to del... Read More about Digital Health Solutions for Weight Loss and Obesity: A Narrative Review.

Effectiveness of short-term isothermic-heat acclimation (4 days) on physical performance in moderately trained males (2022)
Journal Article
Shaw, J., Walkington, C., Cole, E., Gleadall-Siddall, D. O., Burke, R., Bray, J., …Garrett, A. T. (2022). Effectiveness of short-term isothermic-heat acclimation (4 days) on physical performance in moderately trained males. PLoS ONE, 17(11), Article e0270093. https://doi.org/10.1371/journal.pone.0270093

Introduction A typical heat acclimation (HA) protocol takes 5–7 d of 60–90 minutes of heat exposure. Identifying the minimum dose of HA required to elicit a heat adapted phenotype could reduce financial constraints on participants and aid in the tape... Read More about Effectiveness of short-term isothermic-heat acclimation (4 days) on physical performance in moderately trained males.

Resistance training leads to large improvements in strength and moderate improvements in physical function in adults who are overweight or obese: a systematic review (2020)
Journal Article
Orange, S. T., Madden, L. A., & Vince, R. V. (2020). Resistance training leads to large improvements in strength and moderate improvements in physical function in adults who are overweight or obese: a systematic review. Journal of Physiotherapy, 66(4), 214-224. https://doi.org/10.1016/j.jphys.2020.09.009

Questions What are the effects of resistance training on muscle strength, physical function and muscle power in adults who are overweight or obese? Which factors moderate the effects? Design Systematic review of randomised controlled trials, wit... Read More about Resistance training leads to large improvements in strength and moderate improvements in physical function in adults who are overweight or obese: a systematic review.

Impaired heat shock protein 72 expression in women with polycystic ovary syndrome following a supervised exercise programme (2019)
Journal Article
Vince, R. V., Kirk, R. J., Aye, M. M., Atkin, S. L., & Madden, L. A. (2020). Impaired heat shock protein 72 expression in women with polycystic ovary syndrome following a supervised exercise programme. Cell Stress and Chaperones, 25(1), 73-80. https://doi.org/10.1007/s12192-019-01048-1

Induction of heat shock protein expression and the heat shock (stress) response are seen in exercise. This exercise-induced response is thought protective against cellular stress through the expression of heat shock proteins. The highly inducible hea... Read More about Impaired heat shock protein 72 expression in women with polycystic ovary syndrome following a supervised exercise programme.

Feasibility of a novel exercise prehabilitation programme in patients scheduled for elective colorectal surgery: a feasibility randomised controlled trial (2019)
Journal Article
Northgraves, M. J., Arunachalam, L., Madden, L. A., Marshall, P., Hartley, J. E., MacFie, J., & Vince, R. V. (2019). Feasibility of a novel exercise prehabilitation programme in patients scheduled for elective colorectal surgery: a feasibility randomised controlled trial. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, https://doi.org/10.1007/s00520-019-05098-0

© 2019, The Author(s). Background and objectives: To investigate the feasibility of delivering a functional exercise-based prehabilitation intervention and its effects on postoperative length of hospital stay, preoperative physical functioning and he... Read More about Feasibility of a novel exercise prehabilitation programme in patients scheduled for elective colorectal surgery: a feasibility randomised controlled trial.

Effect of home-based resistance training performed with or without a high-speed component in adults with severe obesity (2019)
Journal Article
Orange, S. T., Marshall, P., Madden, L. A., & Vince, R. V. (2020). Effect of home-based resistance training performed with or without a high-speed component in adults with severe obesity. Translational Sports Medicine, 3(1), 34-45. https://doi.org/10.1002/tsm2.115

The objectives of this study were to:(a) evaluate the effects of walking and home-based resistance training on function, strength, power, anthropometry, and quality of life (QoL) in adults with severe obesity, and (b) assess whether performing resist... Read More about Effect of home-based resistance training performed with or without a high-speed component in adults with severe obesity.

The CD105:CD106 microparticle ratio is CD106 dominant in polycystic ovary syndrome compared to type 2 diabetes and healthy subjects (2019)
Journal Article
Al-Qaissi, A., Alqarni, S., Javed, Z., Atkin, S. L., Sathyapalan, T., Vince, R., & Madden, L. A. (2019). The CD105:CD106 microparticle ratio is CD106 dominant in polycystic ovary syndrome compared to type 2 diabetes and healthy subjects. Endocrine, https://doi.org/10.1007/s12020-019-02059-9

© 2019, The Author(s). Background: A retrospective analysis was carried out from patients and controls during the past 5 years from a series of studies investigating endothelial microparticles (MP). Methods: In total, 319 samples from 207 individuals... Read More about The CD105:CD106 microparticle ratio is CD106 dominant in polycystic ovary syndrome compared to type 2 diabetes and healthy subjects.

The effect of exenatide on cardiovascular risk markers in women with polycystic ovary syndrome (2019)
Journal Article
Dawson, A. J., Sathyapalan, T., Vince, R., Coady, A. M., Ajjan, R. A., Kilpatrick, E. S., & Atkin, S. L. (2019). The effect of exenatide on cardiovascular risk markers in women with polycystic ovary syndrome. Frontiers in endocrinology, 10(APR), Article 189. https://doi.org/10.3389/fendo.2019.00189

Background: Polycystic ovary syndrome (PCOS) is associated with an adverse cardiovascular risk profile including a prothrombotic state. Exenatide has been shown to be effective at improving insulin sensitivity and weight loss in PCOS; therefore this... Read More about The effect of exenatide on cardiovascular risk markers in women with polycystic ovary syndrome.

Circulating endothelial microparticles reduce in concentration following an exercise programme in women with polycystic ovary syndrome (2019)
Journal Article
Kirk, R. J., Madden, L. A., Peart, D. J., Aye, M. M., Atkin, S. L., & Vince, R. V. (2019). Circulating endothelial microparticles reduce in concentration following an exercise programme in women with polycystic ovary syndrome. Frontiers in endocrinology, 10(MAR), Article 200. https://doi.org/10.3389/fendo.2019.00200

Purpose: Endothelial dysfunction is a known comorbidity in women with polycystic ovary syndrome (PCOS). The aim was to assess if supervised, moderate intensity exercise could potentially impact markers of endothelial disruption; endothelial cell deri... Read More about Circulating endothelial microparticles reduce in concentration following an exercise programme in women with polycystic ovary syndrome.

Can sit-to-stand muscle power explain the ability to perform functional tasks in adults with severe obesity? (2018)
Journal Article
Orange, S. T., Marshall, P., Madden, L. A., & Vince, R. V. (2019). Can sit-to-stand muscle power explain the ability to perform functional tasks in adults with severe obesity?. Journal of sports sciences, 37(11), 1227-1234. https://doi.org/10.1080/02640414.2018.1553500

This study examined the relationship between sit-to-stand (STS) power and physical function in adults with severe obesity. Thirty-eight adults (age: 44 ± 12 years; body mass index [BMI]: 45.2 ± 7.8 kg/m2) completed evaluations of STS power, strength... Read More about Can sit-to-stand muscle power explain the ability to perform functional tasks in adults with severe obesity?.

Dynamic change in insulin resistance induced by free fatty acids is unchanged though insulin sensitivity improves following endurance exercise in PCOS (2018)
Journal Article
Aye, M. M., Butler, A. E., Kilpatrick, E. S., Kirk, R., Vince, R., Rigby, A. S., …Atkin, S. L. (2018). Dynamic change in insulin resistance induced by free fatty acids is unchanged though insulin sensitivity improves following endurance exercise in PCOS. Frontiers in endocrinology, 9(OCT), Article 592. https://doi.org/10.3389/fendo.2018.00592

Background: Insulin resistance (IR) is the hallmark of PCOS and it is known that exercise may decrease it. What is unknown is whether exercise may mechanistically alter the underlying IR, attenuating the dynamic lipid induced IR in insulin resistant... Read More about Dynamic change in insulin resistance induced by free fatty acids is unchanged though insulin sensitivity improves following endurance exercise in PCOS.

Test-Retest reliability of a commercial linear position transducer (GymAware PowerTool) to measure velocity and power in the Back Squat and Bench Press (2018)
Journal Article
Orange, S. T., Metcalfe, J. W., Vince, R. V., Marshall, P., Madden, L. A., & Liefeith, A. (2020). Test-Retest reliability of a commercial linear position transducer (GymAware PowerTool) to measure velocity and power in the Back Squat and Bench Press. Journal of strength and conditioning research, 34(3), 728-737. https://doi.org/10.1519/JSC.0000000000002715

This study examined the test-retest reliability of the GymAware PowerTool (GYM) to measure velocity and power in the free-weight back squat and bench press. Twenty-nine academy rugby league players (age: 17.6 ± 1.0 years; body mass: 87.3 ± 20.8 kg) c... Read More about Test-Retest reliability of a commercial linear position transducer (GymAware PowerTool) to measure velocity and power in the Back Squat and Bench Press.

Validity and reliability of a wearable inertial sensor to measure velocity and power in the back squat and bench press (2018)
Journal Article
Orange, S. T., Metcalfe, J. W., Liefeith, A., Marshall, P., Madden, L. A., Fewster, C. R., & Vince, R. V. (2019). Validity and reliability of a wearable inertial sensor to measure velocity and power in the back squat and bench press. Journal of strength and conditioning research, 33(9), 2398-2408. https://doi.org/10.1519/JSC.0000000000002574

Orange, ST, Metcalfe, JW, Liefeith, A, Marshall, P, Madden, LA, Fewster, CR, and Vince, RV. Validity and reliability of a wearable inertial sensor to measure velocity and power in the back squat and bench press. J Strength Cond Res 33(9): 2398-2408,... Read More about Validity and reliability of a wearable inertial sensor to measure velocity and power in the back squat and bench press.

Exercise prehabilitation in elective intra-cavity surgery: A role within the ERAS pathway? A narrative review (2018)
Journal Article
Orange, S. T., Northgraves, M. J., Marshall, P., Madden, L. A., & Vince, R. V. (2018). Exercise prehabilitation in elective intra-cavity surgery: A role within the ERAS pathway? A narrative review. International journal of surgery, 56, 328-333. https://doi.org/10.1016/j.ijsu.2018.04.054

The Enhanced Recovery after Surgery (ERAS) model integrates several elements of perioperative care into a standardised clinical pathway for surgical patients. ERAS programmes aim to reduce the rate of complications, improve surgical recovery, and lim... Read More about Exercise prehabilitation in elective intra-cavity surgery: A role within the ERAS pathway? A narrative review.

Short-Term Training and Detraining Effects of Supervised vs. Unsupervised Resistance Exercise in Aging Adults (2018)
Journal Article
Orange, S. T., Marshall, P., Madden, L. A., & Vince, R. V. (2019). Short-Term Training and Detraining Effects of Supervised vs. Unsupervised Resistance Exercise in Aging Adults. Journal of strength and conditioning research, 33(10), 2733-2742. https://doi.org/10.1519/JSC.0000000000002536

Orange, ST, Marshall, P, Madden, LA, and Vince, RV. Short-term training and detraining effects of supervised vs. unsupervised resistance exercise in aging adults. J Strength Cond Res 33(10): 2733-2742, 2019-This study compared the effects of a 4-week... Read More about Short-Term Training and Detraining Effects of Supervised vs. Unsupervised Resistance Exercise in Aging Adults.

The test-retest reliability of four functional mobility tests in apparently healthy adults (2016)
Journal Article
Northgraves, M. J., Hayes, S. C., Marshall, P., Madden, L. A., & Vince, R. V. (2016). The test-retest reliability of four functional mobility tests in apparently healthy adults. Isokinetics and Exercise Science, 24(3), 171-179. https://doi.org/10.3233/ies-160614

Background: Simple field tests are often used to assess functional mobility in clinical settings. Despite having many benefits, these tests are susceptible to measurement error and individual variation. Objectives: To examine the test-retest and abso... Read More about The test-retest reliability of four functional mobility tests in apparently healthy adults.

Implications of a pre-exercise alkalosis-mediated attenuation of HSP72 on its response to a subsequent bout of exercise (2015)
Journal Article
Peart, D. J., Kirk, R. J., Madden, L. A., & Vince, R. V. (2016). Implications of a pre-exercise alkalosis-mediated attenuation of HSP72 on its response to a subsequent bout of exercise. Amino acids, 48(2), 499-504. https://doi.org/10.1007/s00726-015-2103-1

The aim of this study was to investigate if a pre-exercise alkalosis-mediated attenuation of HSP72 had any effect on the response of the same stress protein after a subsequent exercise. Seven physically active males [25.0 ± 6.5 years, 182.1 ± 6.0 cm,... Read More about Implications of a pre-exercise alkalosis-mediated attenuation of HSP72 on its response to a subsequent bout of exercise.