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All Outputs (2)

The synthesis of cationic porphyrins for use in photodynamic antimicrobial chemotherapy (PACT (2008)
Thesis
Hall, C. E. The synthesis of cationic porphyrins for use in photodynamic antimicrobial chemotherapy (PACT. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4212816

Photodynamic therapy (PDT) has been widely used in recent years for the treatment of cancers. However the growing problem of drug resistance in bacteria has led to PDT being used to treat bacterial infections in a new type of therapy called Photodyna... Read More about The synthesis of cationic porphyrins for use in photodynamic antimicrobial chemotherapy (PACT.

Development of synthetic routes towards bis (macrocyclic) compounds for imaging and therapy of cancer (2008)
Thesis
Welch, C. J. Development of synthetic routes towards bis (macrocyclic) compounds for imaging and therapy of cancer. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4208906

Porphyrin molecules are efficient generators of singlet oxygen and are used as photosensitisers in PDT. They are also known to accumulate in tumour tissue due to the hyperpermeability of tumour vasculature and poor lymphatic drainage, thus exhibiting... Read More about Development of synthetic routes towards bis (macrocyclic) compounds for imaging and therapy of cancer.