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Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study (2020)
Journal Article
Nichols, S., Taylor, C., Goodman, T., Page, R., Kallvikbacka-Bennett, A., Nation, F., …Ingle, L. (2020). Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study. International journal of cardiology, https://doi.org/10.1016/j.ijcard.2020.01.044

Background: Routine exercise-based cardiac rehabilitation (CR) may not lead to a substantial increase in peak oxygen uptake (V̇O2peak). This could reduce the potential benefits of CR and explain why CR no longer improves patient survival in recent st... Read More about Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study.

The effect of atorvastatin (and subsequent metformin) on adipose tissue acylation-stimulatory-protein concentration and inflammatory biomarkers in overweight/obese women with polycystic ovary syndrome (2019)
Journal Article
Sathyapalan, T., Hobkirk, J. P., Javed, Z., Carroll, S., Coady, A. M., Pemberton, P., …Atkin, S. L. (2019). The effect of atorvastatin (and subsequent metformin) on adipose tissue acylation-stimulatory-protein concentration and inflammatory biomarkers in overweight/obese women with polycystic ovary syndrome. Frontiers in endocrinology, 10(JUN), https://doi.org/10.3389/fendo.2019.00394

Copyright © 2019 Sathyapalan, Hobkirk, Javed, Carroll, Coady, Pemberton, Smith, Cianflone and Atkin. Background: Atorvastatin has been shown to improve cardiovascular risk (CVR) indices in women with polycystic ovary syndrome (PCOS). Low-grade chroni... Read More about The effect of atorvastatin (and subsequent metformin) on adipose tissue acylation-stimulatory-protein concentration and inflammatory biomarkers in overweight/obese women with polycystic ovary syndrome.

Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective (2019)
Journal Article
Khushhal, A., Nichols, S., Carroll, S., Abt, G., & Ingle, L. (in press). Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective. PloS one, 14(6), https://doi.org/10.1371/journal.pone.0217654

Abstract: Background: In recent years, criticism of the percentage range approach for individualised exercise prescription has intensified and we were concerned that sub-optimal exercise dose (especially intensity) may be in part responsible for the... Read More about Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective.

Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription (2019)
Journal Article
Nichols, S., O'Doherty, A., Carroll, S., & Ingle, L. (in press). Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription. European Journal of Preventive Cardiology, https://doi.org/10.1177/2047487319856432

Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk (2019)
Journal Article
Swainson, M. G., Ingle, L., & Carroll, S. (2019). Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk. Scandinavian Journal of Medicine and Science in Sports, 29(9), 1402-1413. https://doi.org/10.1111/sms.13468

Development of cardiovascular disease (CVD) remains a public health concern for young-to-middle-aged adults, now exacerbated by the increasing prevalence of obesity and sedentary lifestyles. Cardiorespiratory fitness (CRF) improves the reclassificati... Read More about Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk.

Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? : a United Kingdom perspective (2019)
Journal Article
Pymer, S., Nichols, S., Prosser, J., Birkett, S., Carroll, S., & Ingle, L. (in press). Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? : a United Kingdom perspective. European Journal of Preventive Cardiology, https://doi.org/10.1177/2047487319852711

Background: In the United Kingdom (UK), exercise intensity is prescribed from a fixed percentage range (% heart rate reserve; %HRR) in cardiac rehabilitation (CR) programmes. We aimed to determine the accuracy of this approach by comparing it with an... Read More about Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? : a United Kingdom perspective.

Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease - a CARE CR study (2018)
Journal Article
Nichols, S., O'Doherty, A. F., Taylor, C., Clark, A. L., Carroll, S., & Ingle, L. (2019). Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease - a CARE CR study. Clinical physiology and functional imaging, 39(1), 93-102. https://doi.org/10.1111/cpf.12539

BACKGROUND In patients with chronic heart failure, there is a positive linear relationship between skeletal muscle mass (SMM) and peak oxygen consumption (V˙O2peak ); an independent predictor of all-cause mortality. We investigated the association b... Read More about Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease - a CARE CR study.

Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study (2018)
Journal Article
Nichols, S., Taylor, C., Page, R., Kallvikbacka-Bennett, A., Nation, F., Goodman, T., …Ingle, L. (2018). Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study. Sports Medicine - Open, 4(1), https://doi.org/10.1186/s40798-018-0138-z

© 2018, The Author(s). Background: Higher cardiorespiratory fitness (CRF) is associated with lower morbidity and mortality in patients with coronary heart disease (CHD). The mechanisms for this are not fully understood. A more favourable cardiometabo... Read More about Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study.

CARE CR-Cardiovascular and cardiorespiratory Adaptations to Routine Exercise-based Cardiac Rehabilitation: a study protocol for a community-based controlled study with criterion methods (2018)
Journal Article
Nichols, S., Nation, F., Goodman, T., Clark, A. L., Carroll, S., & Ingle, L. (2018). CARE CR-Cardiovascular and cardiorespiratory Adaptations to Routine Exercise-based Cardiac Rehabilitation: a study protocol for a community-based controlled study with criterion methods. BMJ open, 8(1), e019216. https://doi.org/10.1136/bmjopen-2017-019216

Introduction Cardiac rehabilitation (CR) reduces all-cause and cardiovascular mortality in patients with coronary heart disease (CHD). Much of this improvement has been attributed to the beneficial effects of structured exercise training. However, UK... Read More about CARE CR-Cardiovascular and cardiorespiratory Adaptations to Routine Exercise-based Cardiac Rehabilitation: a study protocol for a community-based controlled study with criterion methods.

The effects of acute interval exercise and strawberry intake on postprandial lipemia (2017)
Journal Article
O’Doherty, A., Jones, H. S., Sathyapalan, T., Ingle, L., & Carroll, S. (2017). The effects of acute interval exercise and strawberry intake on postprandial lipemia. Medicine and Science in Sports and Exercise, 49(11), 2315-2323. https://doi.org/10.1249/MSS.0000000000001341

Purpose: Raised postprandial triglycerides (TAG) and related oxidative stresses are strongly associated with increased cardiovascular disease (CVD) risk. Acute exercise and strawberry ingestion independently ameliorate postprandial lipid excursions a... Read More about The effects of acute interval exercise and strawberry intake on postprandial lipemia.

Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation? (2017)
Journal Article
Nichols, S., Gleadall-Siddall, D. O., Antony, R., Clark, A. L., Cleland, J. G. F., Carroll, S., & Ingle, L. (2018). Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation?. Clinical physiology and functional imaging, 38(4), 681-688. https://doi.org/10.1111/cpf.12468

Summary Objective Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method of determining VO2peak. When CPET is unavailable, VO2peak may be estimated from treadmill or cycle ergometer workloads and expressed as estimated metabolic equiva... Read More about Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation?.

Exercise dose and all-cause mortality within extended cardiac rehabilitation: a cohort study (2017)
Journal Article
Taylor, C., Tsakirides, C., Moxon, J., Moxon, J. W., Dudfield, M., Witte, K., …Carroll, S. (2017). Exercise dose and all-cause mortality within extended cardiac rehabilitation: a cohort study. Open heart, 4(2), e000623. https://doi.org/10.1136/openhrt-2017-000623

Aims: To investigate the relationship between exercise participation, exercise ‘dose’ expressed as metabolic equivalent (MET) hours (h) per week, and prognosis in individuals attending an extended, community-based exercise rehabilitation programme. M... Read More about Exercise dose and all-cause mortality within extended cardiac rehabilitation: a cohort study.

Validity and reliability of the Apple Watch for measuring heart rate during exercise (2017)
Journal Article
Khushhal, A., Nichols, S., Evans, W., Gleadall-Siddall, D., Page, R., O'Doherty, A. F., …Abt, G. (2017). Validity and reliability of the Apple Watch for measuring heart rate during exercise. SMIO / Sports Medicine International Open, 1(6), E206-E211. https://doi.org/10.1055/s-0043-120195

We examined the validity and reliability of the Apple Watch heart rate sensor during and in recovery from exercise. Twenty-one males completed treadmill exercise while wearing two Apple Watches (left and right wrists) and a Polar S810i monitor (crite... Read More about Validity and reliability of the Apple Watch for measuring heart rate during exercise.

Vitamin D3 supplementation of a high fat high sugar diet ameliorates prediabetic phenotype in female LDLR–/–and LDLR+/+mice (2017)
Journal Article
Carroll, S., Hobkirk, J., Browning, M. J., Janus, J., Kheder, R., Saeed, Z., & Stover, C. (2017). Vitamin D3 supplementation of a high fat high sugar diet ameliorates prediabetic phenotype in female LDLR–/–and LDLR+/+mice. Immunity, Inflammation and Disease, 5(2), 151-154. https://doi.org/10.1002/iid3.154

© 2017 The Authors. Immunity, Inflammation and Disease Published by John Wiley & Sons Ltd. INTRODUCTION: Fatty liver disease is prevalent in populations with high caloric intake. Nutritherapeutic approaches are being considered, such as supplementa... Read More about Vitamin D3 supplementation of a high fat high sugar diet ameliorates prediabetic phenotype in female LDLR–/–and LDLR+/+mice.

The development of a new sport-specific classification of coping and a meta-analysis of the relationship between different coping strategies and moderators on sporting outcomes (2016)
Journal Article
Nicholls, A. R., Carroll, S., Taylor, N. J., & Perry, J. L. (2016). The development of a new sport-specific classification of coping and a meta-analysis of the relationship between different coping strategies and moderators on sporting outcomes. Frontiers in psychology Frontiers Research Foundation, 7(NOV), 1674-1-1674-14. https://doi.org/10.3389/fpsyg.2016.01674

There is an ever growing coping and sports performance literature, with researchers using many different methods to assess performance and different classifications of coping. As such, it makes it difficult to compare studies and therefore identify h... Read More about The development of a new sport-specific classification of coping and a meta-analysis of the relationship between different coping strategies and moderators on sporting outcomes.

The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise (2016)
Journal Article
O’Doherty, A. F., Sathyapalan, T., Rigby, A. S., Ingle, L., & Carroll, S. (2018). The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise. European Journal of Nutrition, 57(1), 309-318. https://doi.org/10.1007/s00394-016-1320-z

© 2016 The Author(s) Purpose: The Oral Fat Tolerance Test (OFTT) is regarded as a repeatable measure used to assess postprandial triglyceride (TAG) levels, with higher levels observed in cardio-metabolic disorders. Acute aerobic exercise intervention... Read More about The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise.

Submaximal fitness and mortality risk reduction in coronary heart disease: A retrospective cohort study of community-based exercise rehabilitation (2016)
Journal Article
Taylor, C., Tsakirides, C., Moxon, J., Moxon, J. W., Dudfield, M., Witte, K. K., …Carroll, S. (2016). Submaximal fitness and mortality risk reduction in coronary heart disease: A retrospective cohort study of community-based exercise rehabilitation. BMJ open, 6(6), https://doi.org/10.1136/bmjopen-2016-011125

Objectives To examine the association between submaximal cardiorespiratory fitness (sCRF) and all-cause mortality in a cardiac rehabilitation (CR) cohort. Design Retrospective cohort study of participants entering CR between 26 May 1993 and 16 Octob... Read More about Submaximal fitness and mortality risk reduction in coronary heart disease: A retrospective cohort study of community-based exercise rehabilitation.

Effect of a non-dieting lifestyle randomised control trial on psychological well-being and weight management in morbidly obese pre-menopausal women (2015)
Journal Article
Borkoles, E., Carroll, S., Clough, P., & Polman, R. C. (2016). Effect of a non-dieting lifestyle randomised control trial on psychological well-being and weight management in morbidly obese pre-menopausal women. Maturitas, 83, 51-58. https://doi.org/10.1016/j.maturitas.2015.09.010

© 2015 The Authors. Published by Elsevier Ireland Ltd. This is an open access article under the CCBY-NC-ND license. Objective This study examined the effects of a non-dieting lifestyle intervention approach for morbidly obese women designed in the fr... Read More about Effect of a non-dieting lifestyle randomised control trial on psychological well-being and weight management in morbidly obese pre-menopausal women.

Exploring quality of life in patients with and without heart failure (2015)
Journal Article
Zhang, J., Hobkirk, J., Carroll, S., Pellicori, P., Clark, A. L., & Cleland, J. G. (2016). Exploring quality of life in patients with and without heart failure. International journal of cardiology, 202, 676-684. https://doi.org/10.1016/j.ijcard.2015.09.076

Aims The EuroHeart Failure Survey Questionnaire (EHFSQ-1) has 39 questions on symptoms and quality of life (QoL); many items are related. We sought to identify underlying clusters amongst EHFSQ-1 questions, construct an overall “QoL score” and invest... Read More about Exploring quality of life in patients with and without heart failure.

Variability of automated carotid intima-media thickness measurements by novice operators (2014)
Journal Article
Nichols, S., Milner, M., Meijer, R., Carroll, S., & Ingle, L. (2016). Variability of automated carotid intima-media thickness measurements by novice operators. Clinical physiology and functional imaging, 36(1), 25-32. https://doi.org/10.1111/cpf.12189

Carotid intima-media thickness (C-IMT) measurements provide a non-invasive assessment of sub-clinical atherosclerosis. The aim of the study was to assess the inter- and intra-observer variability of automated C-IMT measurements undertaken by two novi... Read More about Variability of automated carotid intima-media thickness measurements by novice operators.