All Outputs (53)

Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study (2023)
Journal Article
James, E., Goodall, S., Nichols, S., Walker, K., Carroll, S., O’Doherty, A. F., & Ingle, L. (2023). Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study. Frontiers in Medicine, 10, Article 1094733. https://doi.org/10.3389/fmed.2023.1094733

Background: Low muscle mass disproportionately affects people with coronary heart disease compared to healthy controls but is under-researched and insufficiently treated. Inflammation, poor nutrition, and neural decline might contribute to low muscle... Read More about Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study.

Metabolic risk is associated with sociodemographic characteristics in adolescents from both rural and urban regions from southern Brazil (2022)
Journal Article
de Souza, S., Francisco de Castro Silveira, J., Marques, K. C., Gaya, A. R., Franke, S. I. R., Renner, J. D. P., Hobkirk, J. P., Carroll, S., & Reuter, C. P. (2022). Metabolic risk is associated with sociodemographic characteristics in adolescents from both rural and urban regions from southern Brazil. BMC Pediatrics, 22(1), Article 324. https://doi.org/10.1186/s12887-022-03386-z

Background: The prevalence of several cardiovascular metabolic disorders are increasingly cause for concern in adolescents worldwide. Given the complex interrelations between metabolic risk (MR) and sociodemographic variables, the present study aims... Read More about Metabolic risk is associated with sociodemographic characteristics in adolescents from both rural and urban regions from southern Brazil.

Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study (2021)
Journal Article
Nichols, S., Engin, B., Carroll, S., Buckley, J., & Ingle, L. (2021). Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study. Annals of physical and rehabilitation medicine, 64(6), Article 101462. https://doi.org/10.1016/j.rehab.2020.101462

Background: Exercise prescription guidelines for individuals undergoing cardiovascular rehabilitation (CR) are often based on heart rate training zones and rating of perceived exertion (RPE). United Kingdom guidelines indicate that patients should ex... Read More about Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study.

Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers (2021)
Journal Article
Marsden, A. J., Riley, D. R., Birkett, S., Rodriguez-Barucg, Q., Guinn, B. A., Carroll, S., Ingle, L., Sathyapalan, T., & Beltran-Alvarez, P. (in press). Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers. Amino acids, https://doi.org/10.1007/s00726-021-03024-5

Cardiovascular disease is the major cause of death worldwide. Extensive cardiovascular biomarkers are available using blood tests but very few, if any, investigations have described non-invasive tests for cardiovascular biomarkers based on readily av... Read More about Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers.

The effects of exercise to promote quality of life in individuals with traumatic brain injuries: a systematic review (2020)
Journal Article
O'Caroll, G., King, S. L., Carroll, S., Perry, J., & Vanicek, N. (in press). The effects of exercise to promote quality of life in individuals with traumatic brain injuries: a systematic review. Brain Injury, 1-13. https://doi.org/10.1080/02699052.2020.1812117

© 2020 Taylor & Francis Group, LLC. Objective: To systematically review the effects of exercise interventions that may enhance quality of life (QOL) in individuals with traumatic brain injury (TBI). Methods: A systematic search was conducted using... Read More about The effects of exercise to promote quality of life in individuals with traumatic brain injuries: a systematic review.

Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication (2020)
Journal Article
Pymer, S., Ibeggazene, S., Palmer, J., Smith, G. E., Carroll, S., Ingle, L., Harwood, A., & Chetter, I. C. (2021). Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication. Journal of Cardiopulmonary Rehabilitation and Prevention, 41(3), 188-193. https://doi.org/10.1097/HCR.0000000000000551

Considering the Feasibility, Tolerability and Safety of High-Intensity Interval Training as a Novel Treatment for Patients with Intermittent Claudication.

Structured Abstract
Purpose: This study assessed the feasibility, tolerability, safety and... Read More about Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication.

Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme (2020)
Journal Article
Khushhal, A., Nichols, S., Carroll, S., Abt, G., & Ingle, L. (in press). Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme. PLoS ONE, 15(8), Article e0237197. https://doi.org/10.1371/journal.pone.0237197

BACKGROUND: Recent concerns have cast doubt over the effectiveness of cardiac rehabilitation [CR] programmes for improving cardiorespiratory fitness [CRF] in patients with a history of cardiac disease in the United Kingdom [UK]. We aimed to character... Read More about Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme.

high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study (2020)
Journal Article
Pymer, S., Harwood, A., Ibeggazene, S., McGregor, G., Huang, C., Twiddy, M., Nicholls, A. R., Ingle, L., Carroll, S., Long, J., Rooms, M., & Chetter, I. C. (2020). high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study. BMJ open, 10(7), Article e038825. https://doi.org/10.1136/bmjopen-2020-038825

Introduction: The first-line recommended treatment for patients with intermittent claudication (IC), is a supervised exercise programme (SEP), which includes a minimum of 2 hours exercise per week over a 12-week period. However, provision, uptake, an... Read More about high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study.

Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study (2020)
Journal Article
Nichols, S., Taylor, C., Goodman, T., Page, R., Kallvikbacka-Bennett, A., Nation, F., Clark, A. L., Birkett, S. T., Carroll, S., & Ingle, L. (2020). Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study. International journal of cardiology, 305, 25-34. https://doi.org/10.1016/j.ijcard.2020.01.044

© 2020 The Authors Background: Recent evidence suggests that routine exercise-based cardiac rehabilitation (CR) may not lead to a substantial increase in estimated peak oxygen uptake (V̇O2peak). This could reduce the potential benefits of CR and expl... Read More about Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study.

The effect of atorvastatin (and subsequent metformin) on adipose tissue acylation-stimulatory-protein concentration and inflammatory biomarkers in overweight/obese women with polycystic ovary syndrome (2019)
Journal Article
Sathyapalan, T., Hobkirk, J. P., Javed, Z., Carroll, S., Coady, A. M., Pemberton, P., Smith, A., Cianflone, K., & Atkin, S. L. (2019). The effect of atorvastatin (and subsequent metformin) on adipose tissue acylation-stimulatory-protein concentration and inflammatory biomarkers in overweight/obese women with polycystic ovary syndrome. Frontiers in endocrinology, 10(JUN), Article 394. https://doi.org/10.3389/fendo.2019.00394

Copyright © 2019 Sathyapalan, Hobkirk, Javed, Carroll, Coady, Pemberton, Smith, Cianflone and Atkin. Background: Atorvastatin has been shown to improve cardiovascular risk (CVR) indices in women with polycystic ovary syndrome (PCOS). Low-grade chroni... Read More about The effect of atorvastatin (and subsequent metformin) on adipose tissue acylation-stimulatory-protein concentration and inflammatory biomarkers in overweight/obese women with polycystic ovary syndrome.

Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective (2019)
Journal Article
Khushhal, A., Nichols, S., Carroll, S., Abt, G., & Ingle, L. (in press). Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective. PLoS ONE, 14(6), Article e0217654. https://doi.org/10.1371/journal.pone.0217654

Abstract:
Background: In recent years, criticism of the percentage range approach for individualised exercise prescription has intensified and we were concerned that sub-optimal exercise dose (especially intensity) may be in part responsible for the... Read More about Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective.

Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription (2019)
Journal Article
Nichols, S., O'Doherty, A., Carroll, S., & Ingle, L. (in press). Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription. European Journal of Preventive Cardiology, https://doi.org/10.1177/2047487319856432

Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk (2019)
Journal Article
Swainson, M. G., Ingle, L., & Carroll, S. (2019). Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk. Scandinavian Journal of Medicine and Science in Sports, 29(9), 1402-1413. https://doi.org/10.1111/sms.13468

Development of cardiovascular disease (CVD) remains a public health concern for young-to-middle-aged adults, now exacerbated by the increasing prevalence of obesity and sedentary lifestyles. Cardiorespiratory fitness (CRF) improves the reclassificati... Read More about Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk.

Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? : a United Kingdom perspective (2019)
Journal Article
Pymer, S., Nichols, S., Prosser, J., Birkett, S., Carroll, S., & Ingle, L. (in press). Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? : a United Kingdom perspective. European Journal of Preventive Cardiology, https://doi.org/10.1177/2047487319852711

Background: In the United Kingdom (UK), exercise intensity is prescribed from a fixed percentage range (% heart rate reserve; %HRR) in cardiac rehabilitation (CR) programmes. We aimed to determine the accuracy of this approach by comparing it
with an... Read More about Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? : a United Kingdom perspective.

Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease - a CARE CR study (2018)
Journal Article
Nichols, S., O'Doherty, A. F., Taylor, C., Clark, A. L., Carroll, S., & Ingle, L. (2019). Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease - a CARE CR study. Clinical physiology and functional imaging, 39(1), 93-102. https://doi.org/10.1111/cpf.12539

BACKGROUND
In patients with chronic heart failure, there is a positive linear relationship between skeletal muscle mass (SMM) and peak oxygen consumption (V˙O2peak ); an independent predictor of all-cause mortality. We investigated the association b... Read More about Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease - a CARE CR study.

Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study (2018)
Journal Article
Nichols, S., Taylor, C., Page, R., Kallvikbacka-Bennett, A., Nation, F., Goodman, T., Clark, A. L., Carroll, S., & Ingle, L. (2018). Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study. Sports Medicine - Open, 4(1), https://doi.org/10.1186/s40798-018-0138-z

© 2018, The Author(s). Background: Higher cardiorespiratory fitness (CRF) is associated with lower morbidity and mortality in patients with coronary heart disease (CHD). The mechanisms for this are not fully understood. A more favourable cardiometabo... Read More about Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study.

CARE CR-Cardiovascular and cardiorespiratory Adaptations to Routine Exercise-based Cardiac Rehabilitation: a study protocol for a community-based controlled study with criterion methods (2018)
Journal Article
Nichols, S., Nation, F., Goodman, T., Clark, A. L., Carroll, S., & Ingle, L. (2018). CARE CR-Cardiovascular and cardiorespiratory Adaptations to Routine Exercise-based Cardiac Rehabilitation: a study protocol for a community-based controlled study with criterion methods. BMJ open, 8(1), e019216. https://doi.org/10.1136/bmjopen-2017-019216

Introduction Cardiac rehabilitation (CR) reduces all-cause and cardiovascular mortality in patients with coronary heart disease (CHD). Much of this improvement has been attributed to the beneficial effects of structured exercise training. However, UK... Read More about CARE CR-Cardiovascular and cardiorespiratory Adaptations to Routine Exercise-based Cardiac Rehabilitation: a study protocol for a community-based controlled study with criterion methods.

The effects of acute interval exercise and strawberry intake on postprandial lipemia (2017)
Journal Article
O’Doherty, A., Jones, H. S., Sathyapalan, T., Ingle, L., & Carroll, S. (2017). The effects of acute interval exercise and strawberry intake on postprandial lipemia. Medicine and Science in Sports and Exercise, 49(11), 2315-2323. https://doi.org/10.1249/MSS.0000000000001341

Purpose: Raised postprandial triglycerides (TAG) and related oxidative stresses are strongly associated with increased cardiovascular disease (CVD) risk. Acute exercise and strawberry ingestion independently ameliorate postprandial lipid excursions a... Read More about The effects of acute interval exercise and strawberry intake on postprandial lipemia.

Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation? (2017)
Journal Article
Nichols, S., Gleadall-Siddall, D. O., Antony, R., Clark, A. L., Cleland, J. G. F., Carroll, S., & Ingle, L. (2018). Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation?. Clinical physiology and functional imaging, 38(4), 681-688. https://doi.org/10.1111/cpf.12468

Summary Objective Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method of determining VO2peak. When CPET is unavailable, VO2peak may be estimated from treadmill or cycle ergometer workloads and expressed as estimated metabolic equiva... Read More about Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation?.

Exercise dose and all-cause mortality within extended cardiac rehabilitation: a cohort study (2017)
Journal Article
Taylor, C., Tsakirides, C., Moxon, J., Moxon, J. W., Dudfield, M., Witte, K., Ingle, L., & Carroll, S. (2017). Exercise dose and all-cause mortality within extended cardiac rehabilitation: a cohort study. Open heart, 4(2), e000623. https://doi.org/10.1136/openhrt-2017-000623

Aims: To investigate the relationship between exercise participation, exercise ‘dose’ expressed as metabolic equivalent (MET) hours (h) per week, and prognosis in individuals attending an extended, community-based exercise rehabilitation programme. M... Read More about Exercise dose and all-cause mortality within extended cardiac rehabilitation: a cohort study.