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high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study (2020)
Journal Article
S, P., AE, H., S, I., G, M., C, H., M, T., …I. C, C. (in press). high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study. BMJ open,

Introduction: The first-line recommended treatment for patients with intermittent claudication (IC), is a supervised exercise programme (SEP), which includes a minimum of 2 hours exercise per week over a 12-week period. However, provision, uptake, an... Read More about high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study.

Presurgery conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease (2019)
Journal Article
Smith, G. E., Palmer, J., Pymer, S., Smith, G. E., Harwood, A. E., Ingle, L., …Chetter, I. C. (2019). Presurgery conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease. The Cochrane database of systematic reviews, 2019(9), https://doi.org/10.1002/14651858.cd013407

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effectiveness of prehabilitation (preoperative exercise, either alone or in combination with nutritional or psychological interventions or both)... Read More about Presurgery conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease.

A systematic review of high-intensity interval training as an exercise intervention for intermittent claudication (2019)
Journal Article
Pymer, S., Palmer, J., Harwood, A. E., Ingle, L., Smith, G. E., & Chetter, I. C. (2019). A systematic review of high-intensity interval training as an exercise intervention for intermittent claudication. Journal of vascular surgery, https://doi.org/10.1016/j.jvs.2019.03.050

Background Intermittent claudication (IC) is the most common symptom of peripheral arterial disease, which significantly affects walking ability, functional capacity and quality of life. Supervised exercise programs (SEP) are recommended as first-lin... Read More about A systematic review of high-intensity interval training as an exercise intervention for intermittent claudication.

Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? : a United Kingdom perspective (2019)
Journal Article
Pymer, S., Nichols, S., Prosser, J., Birkett, S., Carroll, S., & Ingle, L. (in press). Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? : a United Kingdom perspective. European Journal of Preventive Cardiology, https://doi.org/10.1177/2047487319852711

Background: In the United Kingdom (UK), exercise intensity is prescribed from a fixed percentage range (% heart rate reserve; %HRR) in cardiac rehabilitation (CR) programmes. We aimed to determine the accuracy of this approach by comparing it with an... Read More about Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? : a United Kingdom perspective.

Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication (2018)
Journal Article
Harwood, A. E., Totty, J. P., Pymer, S., Huang, C., Hitchman, L., Carradice, D., …Chetter, I. C. (2019). Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication. Journal of vascular surgery, 69(6), 1899-1908.e1. https://doi.org/10.1016/j.jvs.2018.10.065

Objective Intermittent claudication occurs in 20 % of the population over 70 and treatment includes a supervised exercise programme (SEP). Whilst there is evidence demonstrating walking improvements following a SEP there is conflicting data on the ph... Read More about Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication.

Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis (2018)
Journal Article
Pymer, S., Tew, G. A., Palmer, J., Ingle, L., Smith, G. E., Chetter, I., & Harwood, A. E. (2018). Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis. SAGE Open Medicine, 6, 205031211881829. doi:10.1177/2050312118818295

Background: The aim of this updated review is to consider the evidence base for the effectiveness of home-based exercise programmes (HEP) as a treatment option for improving walking distance in patients with IC. Methods: The Medline, EMBASE, CINAHL,... Read More about Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis.


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