All Outputs (2)

Heterogeneity of phenotype and function reflects the multistage development of t follicular helper cells (2017)
Journal Article
Trüb, M., Barr, T. A., Morrison, V. L., Brown, S., Caserta, S., Rixon, J., Ivens, A., & Gray, D. (2017). Heterogeneity of phenotype and function reflects the multistage development of t follicular helper cells. Frontiers in immunology, 8(APR), 489. https://doi.org/10.3389/fimmu.2017.00489

T follicular helper cells (Tfh) provide crucial signals for germinal center (GC) formation, but Tfh populations are heterogeneous. While PD1 hi Tfh are important in the GC response, the function of the PD1 lo Tfh-like subset is unknown. We show that... Read More about Heterogeneity of phenotype and function reflects the multistage development of t follicular helper cells.

CMV-specific T-cell responses at older ages: broad responses with a large central memory component may be key to long-term survival (2017)
Journal Article
Bajwa, M., Vita, S., Vescovini, R., Larsen, M., Sansoni, P., Terrazzini, N., Caserta, S., Thomas, D., Davies, K. A., Smith, H., & Kern, F. (2017). CMV-specific T-cell responses at older ages: broad responses with a large central memory component may be key to long-term survival. The journal of infectious diseases : official publication of the Infectious Diseases Society of America, 215(8), 1212-1220. https://doi.org/10.1093/infdis/jix080

© The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. Cytomegalovirus (CMV) infection sometimes causes large expansions of CMV-specific T cells, particularly in older people. This... Read More about CMV-specific T-cell responses at older ages: broad responses with a large central memory component may be key to long-term survival.