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Visualizing kinetically robust CoIII4L6 assemblies in Vivo: SPECT imaging of the encapsulated [99mTc]TcO4- Anion (2018)
Journal Article
Burke, B. P., Grantham, W., Burke, M. J., Nichol, G. S., Roberts, D., Renard, I., …Lusby, P. J. (2018). Visualizing kinetically robust CoIII4L6 assemblies in Vivo: SPECT imaging of the encapsulated [99mTc]TcO4- Anion. Journal of the American Chemical Society, 140(49), 16877-16881. https://doi.org/10.1021/jacs.8b09582

© 2018 American Chemical Society. Noncovalent encapsulation is an attractive approach for modifying the efficacy and physiochemical properties of both therapeutic and diagnostic species. Abiotic self-assembled constructs have shown promise, yet many... Read More about Visualizing kinetically robust CoIII4L6 assemblies in Vivo: SPECT imaging of the encapsulated [99mTc]TcO4- Anion.

Textural analysis demonstrates heterogeneous [18F]-fluorodeoxyglucose uptake in radiologically normal lung in patients with idiopathic pulmonary fibrosis (2018)
Journal Article
Aliyu, S. A., Avery, G., Cawthorne, C., Archibald, S. J., Kadir, T., Willaime, J. M., …Crooks, M. G. (2018). Textural analysis demonstrates heterogeneous [18F]-fluorodeoxyglucose uptake in radiologically normal lung in patients with idiopathic pulmonary fibrosis. The European respiratory journal, 52(5), 1801138. https://doi.org/10.1183/13993003.01138-2018

Positron Emission Tomography (PET) scanning in idiopathic pulmonary fibrosis (IPF) has revealed increased [18F]-fluorodeoxyglucose ([18F]-FDG) uptake in areas of the lungs that appear normal on high resolution computed tomography (HRCT). We hypothesi... Read More about Textural analysis demonstrates heterogeneous [18F]-fluorodeoxyglucose uptake in radiologically normal lung in patients with idiopathic pulmonary fibrosis.

Bisphosphonate Functionalized Gadolinium Oxide Nanoparticles Allow Long-Term MRI/CT Multimodal Imaging of Calcium Phosphate Bone Cement (2018)
Journal Article
Mastrogiacomo, S., Kownacka, A. E., Dou, W., Burke, B. P., de Rosales, R. T., Heerschap, A., …Walboomers, X. F. (2018). Bisphosphonate Functionalized Gadolinium Oxide Nanoparticles Allow Long-Term MRI/CT Multimodal Imaging of Calcium Phosphate Bone Cement. Advanced Healthcare Materials, 7(19), https://doi.org/10.1002/adhm.201800202

Direct in vivo monitoring of bioconstructs using noninvasive imaging modalities such as magnetic resonance imaging (MRI) or computed tomography (CT) is not possible for many materials. Calcium phosphate–based composites (CPCs) that are applicable to... Read More about Bisphosphonate Functionalized Gadolinium Oxide Nanoparticles Allow Long-Term MRI/CT Multimodal Imaging of Calcium Phosphate Bone Cement.

Increase of Direct C-C Coupling Reaction Yield by Identifying Structural and Electronic Properties of High-Spin Iron Tetra-azamacrocyclic Complexes (2018)
Journal Article
Brewer, S. M., Wilson, K. R., Jones, D. G., Reinheimer, E. W., Archibald, S. J., Prior, T. J., …Green, K. N. (2018). Increase of Direct C-C Coupling Reaction Yield by Identifying Structural and Electronic Properties of High-Spin Iron Tetra-azamacrocyclic Complexes. Inorganic chemistry, 57(15), 8890-8902. https://doi.org/10.1021/acs.inorgchem.8b00777

Macrocyclic ligands have been explored extensively as scaffolds for transition metal catalysts for oxygen and hydrogen atom transfer reactions. C–C reactions facilitated using earth abundant metals bound to macrocyclic ligands have not been well-unde... Read More about Increase of Direct C-C Coupling Reaction Yield by Identifying Structural and Electronic Properties of High-Spin Iron Tetra-azamacrocyclic Complexes.

Plastic scintillator-based microfluidic devices for miniaturized detection of Positron Emission Tomography radiopharmaceuticals (2018)
Journal Article
Tarn, M. D., Kızılyer, N. Y., Esfahani, M. M. N., Joshi, P., Brown, N. J., Pamme, N., …Archibald, S. J. (2018). Plastic scintillator-based microfluidic devices for miniaturized detection of Positron Emission Tomography radiopharmaceuticals. Chemistry : a European journal, 24(52), 13749-13753. https://doi.org/10.1002/chem.201802395

A miniaturized radio-HPLC detector has been developed comprising a microfluidic device fabricated from plastic scintillator in combination with a silicon photomultiplier light sensor, and tested with samples containing a positron-emitting radionuclid... Read More about Plastic scintillator-based microfluidic devices for miniaturized detection of Positron Emission Tomography radiopharmaceuticals.

Synthesis, Crystal Structure, and Cytotoxicity Studies of titanacalix[4 and 8]arene Complexes (2018)
Journal Article
Miller-Shakesby, D. M., Nigam, S., Hughes, D. L., Lopez-Estelles, E., Elsegood, M. R., Cawthorne, C. J., …Redshaw, C. (2018). Synthesis, Crystal Structure, and Cytotoxicity Studies of titanacalix[4 and 8]arene Complexes. Dalton transactions : an international journal of inorganic chemistry / RSoC, 47(27), 8992-8999. https://doi.org/10.1039/c8dt01992d

© 2018 The Royal Society of Chemistry. Reaction of 5,11,17,23-tetra-tert-butyl-dihydroxy-26,28-bis(2-pentoxy)calix[4]arene (L(OH)2(Opentyl)2) with [TiCl4] afforded the dichlorotitanoacalix[4]arene complex [TiCl2L(O)2(Opentyl)2] (1) in good yield. Hyd... Read More about Synthesis, Crystal Structure, and Cytotoxicity Studies of titanacalix[4 and 8]arene Complexes.

Fluoride doped γ-Fe2O3 nanoparticles with increased MRI relaxivity (2018)
Journal Article
Jones, N. E., Burnett, C. A., Salamon, S., Landers, J., Wende, H., Lazzarini, L., …Francesconi, M. G. (2018). Fluoride doped γ-Fe2O3 nanoparticles with increased MRI relaxivity. Journal of Materials Chemistry B, 6(22), 3665-3673. https://doi.org/10.1039/c8tb00360b

Iron oxide nanoparticles (IONs) are being actively researched and experimented with as contrast agents for Magnetic Resonance Imaging (MRI), as well as image-directed delivery of therapeutics. The efficiency of an MRI contrast agent can be described... Read More about Fluoride doped γ-Fe2O3 nanoparticles with increased MRI relaxivity.