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Dual-functionalised shellac nanocarriers give a super-boost of the antimicrobial action of berberine (2018)
Journal Article
Al-Obaidy, S. S., Greenway, G. M., & Paunov, V. N. (in press). Dual-functionalised shellac nanocarriers give a super-boost of the antimicrobial action of berberine. Nanoscale advances, doi:10.1039/c8na00121a

We have developed highly efficient antimicrobial nanocarriers for berberine (BRB) based on shellac nanoparticles (NPs) which were surface-functionalised with a surface active polymer, Poloxamer 407 (P407), and the cationic surfactant octadecyltrimeth... Read More

Microcapsules as assay compartments formed through layer-by-layer deposition (2018)
Journal Article
Alorabi, A. Q., Tarn, M. D., Thomas, M., Paunov, V. N., & Pamme, N. (2018). Microcapsules as assay compartments formed through layer-by-layer deposition. Analytical Methods, 10(44), 5335-5340. doi:10.1039/c8ay02012d

We investigate the potential of using microcapsules, generated through layer-by-layer assembly, as reaction compartments for bioassays. A streptavidin-biotin and an esterase-fluorescein diacetate (FDA) assay were employed for proof-of-concept. Strept... Read More

Amplified antimicrobial action of chlorhexidine encapsulated in PDAC-functionalized acrylate copolymer nanogel carriers (2018)
Journal Article
Al-Awady, M. J., Weldrick, P. J., Hardman, M. J., Greenway, G. M., & Paunov, V. N. (2018). Amplified antimicrobial action of chlorhexidine encapsulated in PDAC-functionalized acrylate copolymer nanogel carriers. Materials Chemistry Frontiers, 2(11), 2032-2044. doi:10.1039/c8qm00343b

We have developed and tested a novel functionalised nanocarrier for chlorhexidine (CHX) which provides a very strong enhancement of its antimicrobial action. The nanocarrier was based on lightly-cross-linked acrylate copolymer nanogel particles loade... Read More

Smart soaps: stimulus responsive soap–hydrogel bead composites for controlled dissolution and release of actives (2018)
Journal Article
Thompson, B. R., Rutkevičius, M., Horozov, T. S., Stoyanov, S. D., & Paunov, V. N. (2018). Smart soaps: stimulus responsive soap–hydrogel bead composites for controlled dissolution and release of actives. Materials Chemistry Frontiers, 2(2), 402-409. doi:10.1039/c7qm00556c

We designed pressure responsive soap–hydrogel bead composites by incorporating agar hydrogel beads of different size distributions within a molten soap matrix at various volume fractions. Upon cooling, the combined suspension of hydrogel beads into t... Read More

Thermally responsive capillary suspensions (2017)
Journal Article
Das, A. A. K., Das, A. A., Dunstan, T. S., Stoyanov, S. D., Starck, P., & Paunov, V. N. (2017). Thermally responsive capillary suspensions. ACS applied materials & interfaces, 9(50), (44152-44160). doi:10.1021/acsami.7b11358. ISSN 1944-8244

© 2017 American Chemical Society. We demonstrate that stimulus-responsive capillary-structured materials can be formed from hydrophobized calcium carbonate particles suspended in a non-polar phase (silicone oil) and bridged by very small amounts of a... Read More

High throughput fabrication of cell spheroids by templating water-in-water Pickering emulsions (2017)
Journal Article
Das, A. A. K., Filby, B. W., Geddes, D. A., Legrande, D., & Paunov, V. N. (2017). High throughput fabrication of cell spheroids by templating water-in-water Pickering emulsions. Materials Horizons, 4(6), 1196-1200. doi:10.1039/c7mh00677b

© The Royal Society of Chemistry 2017. We report a simple technique for the high throughput generation of tissue spheroids based on the encapsulation of dispersed adherent cells in particle-stabilised water-in-water emulsions. We demonstrate cell enc... Read More

Hierarchically porous composites fabricated by hydrogel templating and viscous trapping techniques (2017)
Journal Article
Thompson, B. R., Horozov, T. S., Stoyanov, S. D., & Paunov, V. N. (2017). Hierarchically porous composites fabricated by hydrogel templating and viscous trapping techniques. Materials & design, 137, 384-393. doi:10.1016/j.matdes.2017.10.046

© 2017 Elsevier Ltd Two methods for the preparation of hierarchically porous composites have been developed and explored. The first involved templating mixed slurries of hydrogel beads with two different average bead size distributions with gypsum sl... Read More

Enhanced antimicrobial effect of berberine in nanogel carriers with cationic surface functionality (2017)
Journal Article
Al-Awady, M. J., Fauchet, A., Greenway, G. M., & Paunov, V. N. (2017). Enhanced antimicrobial effect of berberine in nanogel carriers with cationic surface functionality. Journal of materials chemistry B, Materials for biology and medicine /, 5(38), 7885-7897. doi:10.1039/c7tb02262j

We report a strong enhancement in the antimicrobial action of berberine encapsulated into polyacrylic acid-based nanogels followed by further surface functionalisation with a cationic polyelectrolyte (PDAC). Due to the highly developed surface area,... Read More

An ultra melt-resistant hydrogel from food grade carbohydrates (2017)
Journal Article
Thompson, B. R., Horozov, T. S., Stoyanov, S. D., & Paunov, V. N. (2017). An ultra melt-resistant hydrogel from food grade carbohydrates. RSC advances, 7(72), 45535-45544. doi:10.1039/c7ra08590g

© 2017 The Royal Society of Chemistry. We report a binary hydrogel system made from two food grade biopolymers, agar and methylcellulose (agar-MC), which does not require addition of salt for gelation to occur and has very unusual rheological and the... Read More

Structuring and calorie control of bakery products by templating batter with ultra melt-resistant food-grade hydrogel beads (2017)
Journal Article
Thompson, B. R., Horozov, T. S., Stoyanov, S. D., & Paunov, V. N. (2017). Structuring and calorie control of bakery products by templating batter with ultra melt-resistant food-grade hydrogel beads. Food and Function, 8(8), (2967-2973). doi:10.1039/c7fo00867h. ISSN 2042-6496

This journal is © The Royal Society of Chemistry. We report the use of a temperature insensitive, food-grade hydrogel to reduce the caloric density of pancakes that were prepared at temperatures much higher than the boiling point of water. This cheap... Read More

Cancer bioimprinting and cell shape recognition for diagnosis and targeted treatment (2017)
Journal Article
Medlock, J., Das, A. A. K., Madden, L. A., Allsup, D. J., & Paunov, V. N. (2017). Cancer bioimprinting and cell shape recognition for diagnosis and targeted treatment. Chemical Society Reviews, 46(16), (5110-5127). doi:10.1039/c7cs00179g. ISSN 0306-0012

Cancer incidence and mortality have both increased in the last decade and are predicted to continue to rise. Diagnosis and treatment of cancers are often hampered by the inability to specifically target neoplastic cells. Bioimprinting is a promising... Read More

Colloid particle formulations for antimicrobial applications (2017)
Journal Article
Halbus, A. F., Horozov, T. S., & Paunov, V. N. (2017). Colloid particle formulations for antimicrobial applications. Advances in Colloid and Interface Science, 249, 134-148. doi:10.1016/j.cis.2017.05.012

Colloidal particles are being extensively studied in various antimicrobial applications due to their small size to volume ratio and ability to exhibit a wide spectrum of antibacterial, antifungal, antialgal and antiviral action. The present review fo... Read More

Preparation and attachment of liquid-infused porous supra-particles to liquid interfaces (2016)
Journal Article
Al-Shehri, H., Horozov, T. S., & Paunov, V. N. (2016). Preparation and attachment of liquid-infused porous supra-particles to liquid interfaces. Soft matter, 12(40), (8375-8387). doi:10.1039/c6sm01651k. ISSN 1744-683X

© 2016 The Royal Society of Chemistry. We prepared model porous composite supra-particles and investigated the effect of the initial infused fluid phase on their attachment at the liquid-fluid interface. We used a simple method for fabrication of mil... Read More

Attachment of composite porous supra-particles to air–water and oil–water interfaces: theory and experiment (2016)
Journal Article
Paunov, V. N., Al-Shehri, H., & Horozov, T. S. (2016). Attachment of composite porous supra-particles to air–water and oil–water interfaces: theory and experiment. Physical chemistry chemical physics : PCCP, 18(38), (26495-26508). doi:10.1039/c6cp05453f. ISSN 1463-9076

We developed and tested a theoretical model for the attachment of fluid-infused porous supra-particles to a fluid–liquid interface. We considered the wetting behaviour of agglomerated clusters of particles, typical of powdered materials dispersed in... Read More

Fabrication of living soft matter by symbiotic growth of unicellular microorganisms (2016)
Journal Article
Das, A. A. K., Bovill, J., Ayesh, M., Stoyanov, S. D., & Paunov, V. N. (2016). Fabrication of living soft matter by symbiotic growth of unicellular microorganisms. Journal of materials chemistry B, Materials for biology and medicine /, 4(21), (3685-3694). doi:10.1039/c5tb02489g. ISSN 2050-750X

We report the fabrication of living soft matter made as a result of the symbiotic relationship of two unicellular microorganisms. The material is composed of bacterial cellulose produced in situ by acetobacter (Acetobacter aceti NCIMB 8132) in the pr... Read More

Cell shape recognition by colloidal cell imprints: Energy of the cell-imprint interaction (2015)
Journal Article
Borovicka, J., Stoyanov, S. D., & Paunov, V. N. (2015). Cell shape recognition by colloidal cell imprints: Energy of the cell-imprint interaction. Physical review. E, Statistical, nonlinear, and soft matter physics, 92(3), (1-8). doi:10.1103/physreve.92.032730. ISSN 1539-3755

The results presented in this study are aimed at the theoretical estimate of the interactions between a spherical microbial cell and the colloidal cell imprints in terms of the Derjaguin, Landau, Vervey, and Overbeek (DLVO) surface forces. We adapted... Read More