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A pilot study to investigate the role of the 26S proteasome in radiotherapy resistance and loco-regional recurrence following breast conserving therapy for early breast cancer (2011)
Journal Article
ELFadl, D., Hodgkinson, V. C., Long, E. D., Scaife, L., Drew, P. J., Lind, M. J., & Cawkwell, L. (2011). A pilot study to investigate the role of the 26S proteasome in radiotherapy resistance and loco-regional recurrence following breast conserving therapy for early breast cancer. The Breast : official journal of the European Society of Mastology, 20(4), 334-337. https://doi.org/10.1016/j.breast.2011.02.017

Breast conserving therapy is a currently accepted method for managing patients with early stage breast cancer. However, approximately 7% of patients may develop loco-regional tumour recurrence within 5 years. We previously reported that expression of... Read More about A pilot study to investigate the role of the 26S proteasome in radiotherapy resistance and loco-regional recurrence following breast conserving therapy for early breast cancer.

Review article: Reflux in cough and airway disease (2011)
Journal Article
Morice, A. H. (2011). Review article: Reflux in cough and airway disease. Alimentary Pharmacology and Therapeutics, 33(SUPPL. 1), 48-52. https://doi.org/10.1111/j.1365-2036.2011.4581.x

Chronic cough was previously thought to be attributed to three main aetiologies; asthma, reflux and postnasal drip. There is little to differentiate these three different diagnoses in the patients with chronic cough in terms of histology, cytokine pr... Read More about Review article: Reflux in cough and airway disease.

Angiotensin converting enzyme inhibitors effect on endothelial dysfunction: a meta-analysis of randomised controlled trials (2011)
Journal Article
Shahin, Y., Khan, J. A., Samuel, N., & Chetter, I. (2011). Angiotensin converting enzyme inhibitors effect on endothelial dysfunction: a meta-analysis of randomised controlled trials. Atherosclerosis, 216(1), 7-16. https://doi.org/10.1016/j.atherosclerosis.2011.02.044

ObjectiveSeveral studies have assessed the effect of angiotensin converting enzyme inhibitors (ACEIs) on endothelial dysfunction as measured by brachial flow-mediated vasodilatation (FMD). We conducted a meta-analysis to investigate this effect in co... Read More about Angiotensin converting enzyme inhibitors effect on endothelial dysfunction: a meta-analysis of randomised controlled trials.

Repeatedly identified differentially expressed proteins (RIDEPs) from antibody microarray proteomic analysis (2011)
Journal Article
Hodgkinson, V. C., ELFadl, D., Drew, P. J., Lind, M. J., & Cawkwell, L. (2011). Repeatedly identified differentially expressed proteins (RIDEPs) from antibody microarray proteomic analysis. Journal of Proteomics, 74(5), 698-703. https://doi.org/10.1016/j.jprot.2011.02.014

Antibody microarrays are powerful new tools in the field of comparative proteomics. The success of the biomarker discovery pipeline relies on the quality of data generated in the discovery phase and careful selection of proteins for the verification... Read More about Repeatedly identified differentially expressed proteins (RIDEPs) from antibody microarray proteomic analysis.

Randomized clinical trial of endovenous laser ablation compared with conventional surgery for great saphenous varicose veins (2011)
Journal Article
Carradice, D., Mekako, A. I., Mazari, F. A. K., Samuel, N., Hatfield, J., & Chetter, I. C. (2011). Randomized clinical trial of endovenous laser ablation compared with conventional surgery for great saphenous varicose veins. British journal of surgery, 98(4), 501-510. https://doi.org/10.1002/bjs.7394

Background: Endovenous laser ablation (EVLA) is a popular minimally invasive treatment for varicose veins. Surgical treatment, featuring junctional ligation and inversion stripping, has shown excellent clinical and cost effectiveness. The clinical ef... Read More about Randomized clinical trial of endovenous laser ablation compared with conventional surgery for great saphenous varicose veins.

Ultrasound evaluation of carotid body tumours (2011)
Journal Article
Samuel, N., Smith, G., Wolstenhulme, S., & Chetter, I. (2011). Ultrasound evaluation of carotid body tumours. Ultrasound, 19(1), 26-30. https://doi.org/10.1258/ult.2010.010037

Carotid body tumour (CBT) is a rare neoplasm that usually presents as an asymptomatic slow-growing neck mass at the carotid bifurcation. Due to these benign attributes, CBTs often go undiagnosed for a few years before a lateral neck mass becomes clin... Read More about Ultrasound evaluation of carotid body tumours.

Relationship Between Gastro-Oesophageal Reflux and Airway Diseases: The Airway Reflux Paradigm (2011)
Journal Article
Pacheco-Galván, A., Hart, S. P., & Morice, A. H. (2011). Relationship Between Gastro-Oesophageal Reflux and Airway Diseases: The Airway Reflux Paradigm. Archivos de Bronconeumología, 47(4), 195-203. https://doi.org/10.1016/S1579-2129%2811%2970046-5

Our understanding of the relationship between gastro-oesophageal reflux and respiratory disease has recently undergone important changes. The previous paradigm of airway reflux as synonymous with the classic gastro-oesophageal reflux disease (GORD) c... Read More about Relationship Between Gastro-Oesophageal Reflux and Airway Diseases: The Airway Reflux Paradigm.