Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool

Goedegebuur, J.; Abbel, D.; Accassat, S.; Achterberg, W. P.; Akbari, A.; Arfuch, V. M.; Baddeley, E.; Bax, J. J.; Becker, D.; Bergmeijer, B.; Bertoletti, L.; Blom, J. W.; Calvetti, A.; Cannegieter, S. C.; Castro, L.; Chavannes, N. H.; Coma-Auli, N.R.; Couffignal, C.P; Edwards, A.; Edwards, M.; Enggaard, H.; Font, C.; Gava, A.; Geersing, G. J.; Geijteman, E. C.T.; Greenley, S.; Gregory, C.; Gussekloo, J.; Hoffmann, I.; Højen, A. A.; van den Hout, W. B.; Huisman, M. V.; Jacobsen, S.; Jagosh, J.; Johnson, M. J.; Jørgensen, L.; Juffermans, C. C.M.; Kempers, E. K.; Konstantinides, S.; Kroder, A. F.; Kruip, M. J.H.A.; Lafaie, L.; Langendoen, J. W.; Larsen, T. B.; Lifford, K.; van der Linden, Y. M.; Mahé, I.; Maiorana, L.; Maraveyas, A.; Martens, E. S.L.; Mayeur, D.; van Mens, T. E.; Mohr, K.; Mooijaart, S. P.; Murtagh, F. E.M.; Nelson, A.; Nielsen, P. B.; Pearson, M.; Ording, A. G.; Ørskov, M.; Poenou, G.; Portielje, J. E.A.; Raczkiewicz, D.; Rasmussen, K.; Trinks-Roerdink, E.; Schippers, I.; Seddon, K.; Sexton, K.; Sivell, S.; Skjøth, F.; Søgaard, M.; Szmit, S.; Trompet, S.; Vassal, P.; Visser, C.M.; van Vliet, L. M.; Wilson, E.; Klok, F. A.; Noble, S. I.R.

doi:10.1016/j.thromres.2023.05.008

All Outputs (3)

Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making (2024)
Journal Article
Bravington, A., Boland, J. W., Greenley, S., Lind, M., Murtagh, F. E., Patterson, M., Pearson, M., & Johnson, M. J. (2024). Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making. PLoS ONE, 19(1 January), Article e0294218. https://doi.org/10.1371/journal.pone.0294218

Introduction Malignant bowel obstruction is a distressing complication of cancer, causing pain, nausea and vomiting, and often has a poor prognosis. Severe and rapidly developing symptoms, a lack of robust clinical guidelines and the need for multidi... Read More about Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making.

Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction (2023)
Journal Article
Bravington, A., Obita, G., Baddeley, E., Johnson, M., Murtagh, F., Currow, D., Boland, E., Nelson, A., Seddon, K., Oliver, A., Noble, S., & Boland, J. (2023). Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction. PLoS ONE, 18(8), Article e0289501. https://doi.org/10.1371/journal.pone.0289501

Background: Malignant bowel obstruction is experienced by 15% of people with advanced cancer, preventing them from eating and drinking and causing pain, nausea and vomiting. Surgery is not always appropriate. Management options include tube or stent... Read More about Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction.

Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool (2023)
Journal Article
Goedegebuur, J., Abbel, D., Accassat, S., Achterberg, W. P., Akbari, A., Arfuch, V. M., Baddeley, E., Bax, J. J., Becker, D., Bergmeijer, B., Bertoletti, L., Blom, J. W., Calvetti, A., Cannegieter, S. C., Castro, L., Chavannes, N. H., Coma-Auli, N., Couffignal, C., Edwards, A., Edwards, M., …Noble, S. I. (2023). Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool. Thrombosis Research, 228, 54-60. https://doi.org/10.1016/j.thromres.2023.05.008

BACKGROUND: Even though antithrombotic therapy has probably little or even negative effects on the well-being of people with cancer during their last year of life, deprescribing antithrombotic therapy at the end of life is rare in practice. It is oft... Read More about Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool.