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All Outputs (33)

Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication (2018)
Journal Article
Harwood, A. E., Totty, J. P., Pymer, S., Huang, C., Hitchman, L., Carradice, D., …Chetter, I. C. (2019). Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication. Journal of vascular surgery, 69(6), 1899-1908.e1. https://doi.org/10.1016/j.jvs.2018.10.065

Objective Intermittent claudication occurs in 20 % of the population over 70 and treatment includes a supervised exercise programme (SEP). Whilst there is evidence demonstrating walking improvements following a SEP there is conflicting data on the ph... Read More about Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication.

High risk (B3) breast lesions: What is the incidence of malignancy for individual lesion subtypes? A systematic review and meta-analysis (2018)
Journal Article
Forester, N. D., Lowes, S., Mitchell, E., & Twiddy, M. (2019). High risk (B3) breast lesions: What is the incidence of malignancy for individual lesion subtypes? A systematic review and meta-analysis. European journal of surgical oncology, 45(4), 519-527. https://doi.org/10.1016/j.ejso.2018.12.008

© 2018 Introduction: Provide evidence to support evolving management strategies for high-risk (B3) breast lesions by assessing risk of carcinoma in subgroups of B3 lesions using systematic review and meta-analysis. Methods: Databases identified obser... Read More about High risk (B3) breast lesions: What is the incidence of malignancy for individual lesion subtypes? A systematic review and meta-analysis.

Hidden morbidity: the results of a collaborative community chronic obstructive pulmonary disease screening initiative (2018)
Journal Article
Crooks, M. G., Thompson, J. L., Cummings, H., Watkins, K., Jackson, N., Platten, S., …Faruqi, S. (2019). Hidden morbidity: the results of a collaborative community chronic obstructive pulmonary disease screening initiative. Clinical Respiratory Journal, 13(1), 43-49. https://doi.org/10.1111/crj.12978

Chronic obstructive pulmonary disease (COPD) often goes unrecognised resulting in people living with the disease without a diagnosis. We investigated the characteristics, symptom burden and flow of participants in a community COPD screening initiativ... Read More about Hidden morbidity: the results of a collaborative community chronic obstructive pulmonary disease screening initiative.

Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis (2018)
Journal Article
Pymer, S. A., Tew, G. A., Palmer, J., Ingle, L., Smith, G. E., Chetter, I. C., & Harwood, A. E. (2018). Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis. SAGE Open Medicine, 6, https://doi.org/10.1177/2050312118818295

Background: The aim of this updated review is to consider the evidence base for the effectiveness of home-based exercise programmes as a treatment option for improving walking distance in patients with intermittent claudication. Methods: The Medline,... Read More about Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis.

Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 (2018)
Journal Article
James, S. L., Theadom, A., Ellenbogen, R. G., Bannick, M. S., Montjoy-Venning, W., Lucchesi, L. R., …Murray, C. J. L. (2019). Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurology, 18(1), 56-87. https://doi.org/10.1016/S1474-4422%2818%2930415-0

Background Traumatic brain injury (TBI) and spinal cord injury (SCI) are increasingly recognised as global health priorities in view of the preventability of most injuries and the complex and expensive medical care they necessitate. We aimed to measu... Read More about Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016.

Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016 (2018)
Journal Article
Soyiri, I., & GBD 2016 Neurology Collaborators. (2018). Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurology, https://doi.org/10.1016/S1474-4422%2818%2930499-X

Background Traumatic brain injury (TBI) and spinal cord injury (SCI) are increasingly recognised as global health priorities in view of the preventability of most injuries and the complex and expensive medical care they necessitate. We aimed to measu... Read More about Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.

TIGA-CUB-manualised psychoanalytic child psychotherapy versus treatment as usual for children aged 5–11 with treatment-resistant conduct disorders and their primary carers: results from a randomised controlled feasibility trial (2018)
Journal Article
Edginton, E., Walwyn, R., Twiddy, M., Wright-Hughes, A., Tubeuf, S., Reed, S., …Cottrell, D. (2018). TIGA-CUB-manualised psychoanalytic child psychotherapy versus treatment as usual for children aged 5–11 with treatment-resistant conduct disorders and their primary carers: results from a randomised controlled feasibility trial. Journal of Child and Adolescent Mental Health, 30(3), 167-182. https://doi.org/10.2989/17280583.2018.1532433

Background: Parenting programmes are recommended for conduct disorders in 5–11 year olds, but ineffective for 25–33%. A feasibility trial was needed to determine whether a confirmatory trial of second-line, manualised short-term psychoanalytic child... Read More about TIGA-CUB-manualised psychoanalytic child psychotherapy versus treatment as usual for children aged 5–11 with treatment-resistant conduct disorders and their primary carers: results from a randomised controlled feasibility trial.

Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017 (2018)
Journal Article
Stanaway, J. D., Afshin, A., Gakidou, E., Lim, S. S., Abate, D., Abate, K. H., …Murray, C. J. L. (2018). Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017. Lancet, 392(10159), 1923-1994. https://doi.org/10.1016/S0140-6736%2818%2932225-6

Background The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising evidence on risks and risk–ou... Read More about Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017.

Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017 (2018)
Journal Article
Bin Sayeed, M. S., Lozano, R., Fullman, N., Abate, D., Abay, S. M., Abbafati, C., …Murray, C. J. L. (2018). Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017. Lancet, 392(10159), 2091-2138. https://doi.org/10.1016/s0140-6736%2818%2932281-5

Background Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of “leaving... Read More about Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017.

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017 (2018)
Journal Article
Roth, G. A., Abate, D., Abate, K. H., Abay, S. M., Abbafati, C., Abbasi, N., …Murray, C. J. L. (2018). Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet, 392(10159), 1736-1788. https://doi.org/10.1016/S0140-6736%2818%2932203-7

Background Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, nation... Read More about Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017.

Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: A systematic analysis for the Global Burden of Disease Study 2017 (2018)
Journal Article
Dicker, D., Nguyen, G., Abate, D., Abate, K. H., Abay, S. M., Abbafati, C., …Murray, C. J. L. (2018). Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: A systematic analysis for the Global Burden of Disease Study 2017. Lancet, 392(10159), 1684-1735. https://doi.org/10.1016/S0140-6736%2818%2931891-9

Background Assessments of age-specific mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Affairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Glo... Read More about Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: A systematic analysis for the Global Burden of Disease Study 2017.

Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017 (2018)
Journal Article
Kyu, H. H., Abate, D., Abate, K. H., Abay, S. M., Abbafati, C., Abbasi, N., …Murray, C. J. L. (2018). Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017. Lancet, 392(10159), 1859-1922. https://doi.org/10.1016/S0140-6736%2818%2932335-3

Background How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and provision of services.... Read More about Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017.

Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017 (2018)
Journal Article
Naik, G., James, S. L., Abate, D., Abate, K. H., Abay, S. M., Abbafati, C., …Murray, C. J. L. (2018). Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017. Lancet, 392(10159), 1789-1858. https://doi.org/10.1016/S0140-6736%2818%2932279-7

Background The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990... Read More about Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017.

Population and fertility by age and sex for 195 countries and territories, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017 (2018)
Journal Article
Murray, C. J. L., Callender, C. S. K. H., Kulikoff, X. R., Srinivasan, V., Abate, D., Abate, K. H., …Lim, S. S. (2018). Population and fertility by age and sex for 195 countries and territories, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet, 392(10159), 1995-2051. https://doi.org/10.1016/S0140-6736%2818%2932278-5

© 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Background: Population estimates underpin demographic and epidemiological research and are used to track progress on numerous international in... Read More about Population and fertility by age and sex for 195 countries and territories, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017.

A validation and calibration process for self-reported tobacco use with participants’ cotinine levels: an example from the Building Blocks trial (2018)
Journal Article
Huang, C., Roberts, Z., Cannings-John, R., Sanders, J., Pickett, K., Montgomery, A., & Robling, M. (2019). A validation and calibration process for self-reported tobacco use with participants’ cotinine levels: an example from the Building Blocks trial. Nicotine and Tobacco Research, 21(12), 1660-1664. https://doi.org/10.1093/ntr/nty232

Reducing smoking in pregnancy was a primary outcome in our Building Blocks trial of the Family Nurse Partnership. We calibrated maternal reports of smoking using cotinine values derived from urine samples to assess tobacco use. This involves identify... Read More about A validation and calibration process for self-reported tobacco use with participants’ cotinine levels: an example from the Building Blocks trial.

A prospective, mixed-methods, before and after study to identify the evidence base for the core components of an effective Paediatric Early Warning System and the development of an implementation package containing those core recommendations for use in the UK: Paediatric early warning system - utilisation and mortality avoidance- the PUMA study protocol (2018)
Journal Article
Thomas-Jones, E., Lloyd, A., Roland, D., Sefton, G., Tume, L., Hood, K., …Powell, C. (2018). A prospective, mixed-methods, before and after study to identify the evidence base for the core components of an effective Paediatric Early Warning System and the development of an implementation package containing those core recommendations for use in the UK: Paediatric early warning system - utilisation and mortality avoidance- the PUMA study protocol. BMC Pediatrics, 18(1), Article 244. https://doi.org/10.1186/s12887-018-1210-z

© 2018 The Author(s). Background: In hospital, staff need to routinely monitor patients to identify those who are seriously ill, so that they receive timely treatment to improve their condition. A Paediatric Early Warning System is a multi-faceted so... Read More about A prospective, mixed-methods, before and after study to identify the evidence base for the core components of an effective Paediatric Early Warning System and the development of an implementation package containing those core recommendations for use in the UK: Paediatric early warning system - utilisation and mortality avoidance- the PUMA study protocol.

High health gain patients with asthma: a cross-sectional study analysing national Scottish data sets (2018)
Journal Article
Mukherjee, M., Nwaru, B. I., Soyiri, I., Grant, I., & Sheikh, A. (2018). High health gain patients with asthma: a cross-sectional study analysing national Scottish data sets. NPJ Primary Care Respiratory Medicine, 28, Article 27. https://doi.org/10.1038/s41533-018-0094-6

Studies have shown that a small proportion of patients have particularly high needs and are responsible for disproportionally high disease burden. Estimates suggest that 2–5% of patients are high users of healthcare for their health gain. Such patien... Read More about High health gain patients with asthma: a cross-sectional study analysing national Scottish data sets.

Determinants of physiological uptake of 18F-fluorodeoxyglucose in palatine tonsils (2018)
Journal Article
Birkin, E., Moore, K. S., Huang, C., Christopher, M., Rees, J. I., Jayaprakasam, V., & Fielding, P. A. (2018). Determinants of physiological uptake of 18F-fluorodeoxyglucose in palatine tonsils. Medicine, 97(24), Article e11040. https://doi.org/10.1097/md.0000000000011040

To determine the extent of physiological variation of uptake of 18F-flurodeoxyglucose (FDG) within palatine tonsils. To define normal limits for side-to-side variation and characterize factors affecting tonsillar uptake of FDG. Over a period of 16... Read More about Determinants of physiological uptake of 18F-fluorodeoxyglucose in palatine tonsils.

Exogenous sex steroid hormones and asthma in females: protocol for a population-based retrospective cohort study using a UK primary care database (2018)
Journal Article
Nwaru, B. I., Simpson, C. R., Soyiri, I. N., Pillinger, R., Appiagyei, F., Ryan, D., …Sheikh, A. (2018). Exogenous sex steroid hormones and asthma in females: protocol for a population-based retrospective cohort study using a UK primary care database. BMJ open, 8(6), Article e020075. https://doi.org/10.1136/bmjopen-2017-020075

© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Introduction Female sex steroid hormones have been implicated in sex-related differences in the development... Read More about Exogenous sex steroid hormones and asthma in females: protocol for a population-based retrospective cohort study using a UK primary care database.

Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: A systematic analysis from the Global Burden of Disease Study 2016 (2018)
Journal Article
Fullman, N., Yearwood, J., Abay, S. M., Abbafati, C., Abd-Allah, F., Abdela, J., …Lozano, R. (2018). Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: A systematic analysis from the Global Burden of Disease Study 2016. Lancet, 391(10136), 2236-2271. https://doi.org/10.1016/S0140-6736%2818%2930994-2

Copyright © 2018 The Author(s). Published by Elsevier Ltd. Background A key component of achieving universal health coverage is ensuring that all populations have access to quality health care. Examining where gains have occurred or progress has falt... Read More about Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: A systematic analysis from the Global Burden of Disease Study 2016.