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A hypoplastic model of skeletal muscle development displaying reduced foetal myoblast cell numbers, increased oxidative myofibres and improved specific tension capacity (2010)
Journal Article
Otto, A., Macharia, R., Matsakas, A., Valasek, P., Mankoo, B. S., & Patel, K. (2010). A hypoplastic model of skeletal muscle development displaying reduced foetal myoblast cell numbers, increased oxidative myofibres and improved specific tension capacity. Developmental Biology, 343(1-2), (51-62). doi:10.1016/j.ydbio.2010.04.014. ISSN 1095-564X

The major component of skeletal muscle is the myofibre. Genetic intervention inducing over-enlargement of myofibres beyond a certain threshold through acellular growth causes a reduction in the specific tension generating capacity of the muscle. Howe... Read More about A hypoplastic model of skeletal muscle development displaying reduced foetal myoblast cell numbers, increased oxidative myofibres and improved specific tension capacity.