All Outputs (190)

Mechanisms of growth inhibition of primary prostate epithelial cells following gamma irradiation or photodynamic therapy including senscence, necrosis, and autophagy, but not apoptosis (2015)
Journal Article
Frame, F. M., Savoie, H., Bryden, F., Giuntini, F., Mann, V. M., Simms, M. S., Boyle, R. W., & Maitland, N. J. (2016). Mechanisms of growth inhibition of primary prostate epithelial cells following gamma irradiation or photodynamic therapy including senscence, necrosis, and autophagy, but not apoptosis. Cancer medicine, 5(1), 61-73. https://doi.org/10.1002/cam4.553

In comparison to more differentiated cells, prostate cancer stem-like cells are radioresistant, which could explain radio-recurrent prostate cancer. Improvement of radiotherapeutic efficacy may therefore require combination therapy. We have investiga... Read More about Mechanisms of growth inhibition of primary prostate epithelial cells following gamma irradiation or photodynamic therapy including senscence, necrosis, and autophagy, but not apoptosis.

Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin (2015)
Journal Article
Entract, G. M., Bryden, F., Domarkas, J., Savoie, H., Allott, L., Archibald, S. J., Cawthorne, C., & Boyle, R. W. (2015). Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin. Molecular pharmaceutics, 12(12), 4414-4423. https://doi.org/10.1021/acs.molpharmaceut.5b00606

Synthesis of the first water-soluble porphyrin radiolabeled with fluorine-18 is described: a new molecular theranostic agent which integrates the therapeutic selectivity of photodynamic therapy (PDT) with the imaging efficacy of positron emission tom... Read More about Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin.

Thermographic laser Doppler velocimetry (2015)
Journal Article
Ojo, A. O., Fond, B., Van Wachem, B. G. M., Heyes, A. L., & Beyrau, F. (2015). Thermographic laser Doppler velocimetry. Optics letters, 40(20), 4759-4762. https://doi.org/10.1364/ol.40.004759

We propose a point measurement technique for simultaneous gas temperature and velocity measurement based on thermographic phosphor particles dispersed in the fluid. The flow velocity is determined from the frequency of light scattered by BaMgAl10O17:... Read More about Thermographic laser Doppler velocimetry.

3-(4-Bromophenyl)-5-(4-hydroxyphenyl)isoxazole: a versatile, new molecular building block for side-chain liquid crystal oligomers and polymers (2015)
Journal Article
Vilela, G. D., Fernandes, T. H. M., da Rosa, R. R., Kelly, S. M., Kitney, S. P., & Merlo, A. A. (2016). 3-(4-Bromophenyl)-5-(4-hydroxyphenyl)isoxazole: a versatile, new molecular building block for side-chain liquid crystal oligomers and polymers. Polymer Bulletin, 73(4), 959-973. https://doi.org/10.1007/s00289-015-1529-7

The synthesis and liquid crystalline behaviour of new comb-shaped methacrylate oligomers, derived from a new key intermediate in the synthesis of heterocyclic liquid crystals, i.e., 3-(4-bromophenyl)-5-(4-hydroxyphenyl)isoxazole, are reported. These... Read More about 3-(4-Bromophenyl)-5-(4-hydroxyphenyl)isoxazole: a versatile, new molecular building block for side-chain liquid crystal oligomers and polymers.

Site-selective multi-porphyrin attachment enables the formation of a next-generation antibody-based photodynamic therapeutic (2015)
Journal Article
Maruani, A., Savoie, H., Bryden, F., Caddick, S., Boyle, R., & Chudasama, V. (2015). Site-selective multi-porphyrin attachment enables the formation of a next-generation antibody-based photodynamic therapeutic. Chemical communications : Chem comm / the Royal Society of Chemistry, 51(83), 15304-15307. https://doi.org/10.1039/c5cc06985h

Herein we present a significant step towards next-generation antibody-based photodynamic therapeutics. Site-selective modification of a clinically relevant monoclonal antibody, with a serum-stable linker bearing a strained alkyne, allows for the cont... Read More about Site-selective multi-porphyrin attachment enables the formation of a next-generation antibody-based photodynamic therapeutic.

Büchwald-Hartwig reaction applied to synthesis of new luminescent liquid crystal triarylamines derived from isoxazoles (2015)
Journal Article
Vilela, G. D., Fernandes, T. H. M., Kelly, S. M., & Merlo, A. A. (2015). Büchwald-Hartwig reaction applied to synthesis of new luminescent liquid crystal triarylamines derived from isoxazoles. Molecular crystals and liquid crystals, 612(1), 169-182. https://doi.org/10.1080/15421406.2015.1030982

© 2015 Taylor & Francis Group, LLC. The present work describes the synthesis and characterization of novel series of triarylamines isoxazoles (TAA) addressed to the organic photovoltaic materials. Diarylisoxazoles were synthesized by sequential [3+... Read More about Büchwald-Hartwig reaction applied to synthesis of new luminescent liquid crystal triarylamines derived from isoxazoles.

Effects of low seawater pH on the marine polychaete Platynereis dumerilii (2015)
Journal Article
Wäge, J., Hardege, J. D., Larsson, T. A., Simakov, O., Chapman, E. C., Arendt, D., & Rotchell, J. M. (2015). Effects of low seawater pH on the marine polychaete Platynereis dumerilii. Marine pollution bulletin, 95(1), 166-172. https://doi.org/10.1016/j.marpolbul.2015.04.027

An important priority for any organism is to maintain internal cellular homeostasis including acidbase balance. Yet, the molecular level impacts of changing environmental conditions, such as low pH, remain uncharacterised. Herein, we isolate partial... Read More about Effects of low seawater pH on the marine polychaete Platynereis dumerilii.

PET/PDT theranostics: Synthesis and biological evaluation of a peptide-targeted gallium porphyrin (2015)
Journal Article
Bryden, F., Savoie, H., Rosca, E. V., & Boyle, R. W. (2015). PET/PDT theranostics: Synthesis and biological evaluation of a peptide-targeted gallium porphyrin. Dalton Transactions : an international journal of inorganic chemistry, 44(11), 4925-4932. https://doi.org/10.1039/c4dt02949f

The development of novel theranostic agents is an important step in the pathway towards personalised medicine, with the combination of diagnostic and therapeutic modalities into a single treatment agent naturally lending itself to the optimisation an... Read More about PET/PDT theranostics: Synthesis and biological evaluation of a peptide-targeted gallium porphyrin.

Studies on the sulfation of cellulose α-lipoate and ability of the sulfated product to stabilize colloidal suspensions of gold nanoparticles (2015)
Journal Article
Sarbova, V., Koschella, A., Cheng, F., Kelly, S. M., & Heinze, T. (2015). Studies on the sulfation of cellulose α-lipoate and ability of the sulfated product to stabilize colloidal suspensions of gold nanoparticles. Carbohydrate Polymers, 124, 117-123. https://doi.org/10.1016/j.carbpol.2015.01.080

© 2015 Elsevier Ltd. A versatile method for the synthesis of cellulose α-lipoate with a low degree of substitution (DS) has been developed using N,N-dimethylacetamide (DMA)/LiCl as a solvent and N,N′-carbonyldiimidazole (CDI) as an esterification rea... Read More about Studies on the sulfation of cellulose α-lipoate and ability of the sulfated product to stabilize colloidal suspensions of gold nanoparticles.

Secondary contact seeds phenotypic novelty in cichlid fishes (2015)
Journal Article
Nichols, P., Genner, M. J., van Oosterhout, C., Smith, A., Parsons, P., Sungani, H., Swanstrom, J., & Joyce, D. A. (2015). Secondary contact seeds phenotypic novelty in cichlid fishes. Proceedings of the Royal Society B: Biological Sciences, 282(1798), Article ARTN 20142272. https://doi.org/10.1098/rspb.2014.2272

Theory proposes that genomic admixture between formerly reproductively isolated populations can generate phenotypic novelty for selection to act upon. Secondary contact may therefore be a significant promoter of phenotypic novelty that allows species... Read More about Secondary contact seeds phenotypic novelty in cichlid fishes.

Microwave oven fabricated hybrid memristor devices for non-volatile memory storage (2014)
Journal Article
Verrelli, E., Gray, R. J., O'Neill, M., Kelly, S. M., & Kemp, N. T. (2014). Microwave oven fabricated hybrid memristor devices for non-volatile memory storage. Materials Research Express, 1(4), Article ARTN 046305. https://doi.org/10.1088/2053-1591/1/4/046305

© 2014 IOP Publishing Ltd. Novel hybrid non-volatile memories made using an ultra-fast microwave heating method are reported for the first time. The devices, consisting of aligned ZnO nanorods embedded in poly (methyl methacrylate), require no formin... Read More about Microwave oven fabricated hybrid memristor devices for non-volatile memory storage.

Green synthesis of highly concentrated aqueous colloidal solutions of large starch-stabilised silver nanoplatelets (2014)
Journal Article
Cheng, F., Betts, J. W., Kelly, S. M., & Hector, A. L. (2015). Green synthesis of highly concentrated aqueous colloidal solutions of large starch-stabilised silver nanoplatelets. Materials Science and Engineering: C, 46, 530-537. https://doi.org/10.1016/j.msec.2014.10.041

© 2014 Elsevier B.V. All rights reserved. A simple, environmentally friendly and cost-effective method has been developed to prepare a range of aqueous silver colloidal solutions, using ascorbic acid as a reducing agent,water-soluble starch as a comb... Read More about Green synthesis of highly concentrated aqueous colloidal solutions of large starch-stabilised silver nanoplatelets.

UV-stable paper coated with APTES-modified P25 TiO₂ nanoparticles (2014)
Journal Article
Cheng, F., Sajedin, S. M., Kelly, S. M., Lee, A. F., & Kornherr, A. (2014). UV-stable paper coated with APTES-modified P25 TiO₂ nanoparticles. Carbohydrate Polymers, 114, 246-252. https://doi.org/10.1016/j.carbpol.2014.07.076

In order to inhibit the photocatalytic degradation of organic material supports induced by small titania (TiO₂) nanoparticles, highly photocatalytically active, commercially available P25-TiO₂ nanoparticles were first modified with a thin layer of (3... Read More about UV-stable paper coated with APTES-modified P25 TiO₂ nanoparticles.

Whiter, brighter, and more stable cellulose paper coated with antibacterial carboxymethyl starch stabilized ZnO nanoparticles (2014)
Journal Article
Cheng, F., Betts, J. W., Kelly, S. M., Wareham, D. W., Kornherr, A., Dumestre, F., Schaller, J., & Heinze, T. (2014). Whiter, brighter, and more stable cellulose paper coated with antibacterial carboxymethyl starch stabilized ZnO nanoparticles. Journal of Materials Chemistry B, 2(20), 3057-3064. https://doi.org/10.1039/c3tb21734e

Small, carboxymethyl-starch-stabilised zinc oxide nanoparticles with a defined shape, size and morphology were prepared in situ in water at relatively low reaction temperatures using soluble carboxymethyl starch (CMS) as a combined crystallising, sta... Read More about Whiter, brighter, and more stable cellulose paper coated with antibacterial carboxymethyl starch stabilized ZnO nanoparticles.

Regioselective and stoichiometrically controlled conjugation of photodynamic sensitizers to a HER2 targeting antibody fragment (2014)
Journal Article
Bryden, F., Maruani, A., Savoie, H., Chudasama, V., Smith, M. E. B., Caddick, S., & Boyle, R. W. (2014). Regioselective and stoichiometrically controlled conjugation of photodynamic sensitizers to a HER2 targeting antibody fragment. Bioconjugate chemistry, 25(3), 611-617. https://doi.org/10.1021/bc5000324

The rapidly increasing interest in the synthesis of antibody–drug conjugates as powerful targeted anticancer agents demonstrates the growing appreciation of the power of antibodies and antibody fragments as highly selective targeting moieties. This t... Read More about Regioselective and stoichiometrically controlled conjugation of photodynamic sensitizers to a HER2 targeting antibody fragment.

Solution-processed bilayer photovoltaic devices with nematic liquid crystals (2013)
Journal Article
AlKhalifah, M. S., Lei, C., Myers, S. A., O’Neill, M., Kitney, S. P., & Kelly, S. M. (2014). Solution-processed bilayer photovoltaic devices with nematic liquid crystals. Liquid crystals, 41(3), 402-417. https://doi.org/10.1080/02678292.2013.834082

The cross-linking of polymerisable liquid crystalline semiconductors is a promising approach to solution-processable, multilayer, organic photovoltaics. Here we demonstrate an organic bilayer photovoltaic with an insoluble electron-donating layer for... Read More about Solution-processed bilayer photovoltaic devices with nematic liquid crystals.

The Manichean temptation: Moralising rhetoric and the invocation of evil in US foreign policy (2013)
Journal Article
Kennedy, C. (2013). The Manichean temptation: Moralising rhetoric and the invocation of evil in US foreign policy. International Politics, 50(5), 623-638. https://doi.org/10.1057/ip.2013.26

The United States, Richard Hofstadter once remarked, is a country that has the misfortune not to have an ideology but to be one. In this article, an amendment to Hofstadter's claim is made, suggesting that tied in with the United States's sense of se... Read More about The Manichean temptation: Moralising rhetoric and the invocation of evil in US foreign policy.

The removal of thermally aged films of triacylglycerides by surfactant solutions (2013)
Journal Article
Dunstan, T. S., & Fletcher, P. D. I. (2014). The removal of thermally aged films of triacylglycerides by surfactant solutions. Journal of surfactants and detergents, 17(5), 899-910. https://doi.org/10.1007/s11743-013-1514-9

Thermal ageing of triacylglycerides (TAG) at high temperatures produces films which resist removal using aqueous surfactant solutions. We used a mass loss method to investigate the removal of thermally aged TAG films from hard surfaces using aqueous... Read More about The removal of thermally aged films of triacylglycerides by surfactant solutions.

Whiter, brighter, and more stable cellulose paper coated with TiO 2/SiO2 core/shell nanoparticles using a layer-by-layer approach (2013)
Journal Article
Cheng, F., Lorch, M., Sajedin, S. M., Kelly, S. M., & Kornherr, A. (2013). Whiter, brighter, and more stable cellulose paper coated with TiO 2/SiO2 core/shell nanoparticles using a layer-by-layer approach. ChemSusChem, 6(8), 1392-1399. https://doi.org/10.1002/cssc.201300305

To inhibit the photocatalytic degradation of organic material supports induced by small titania (TiO2) nanoparticles, four kinds of TiO2 nanoparticles, that is, commercial P25-TiO2, commercial rutile phase TiO2, rutile TiO2 nanorods and rutile TiO2 s... Read More about Whiter, brighter, and more stable cellulose paper coated with TiO 2/SiO2 core/shell nanoparticles using a layer-by-layer approach.

The influence of the nematic phase on the phase separation of blended organic semiconductors for photovoltaics (2013)
Journal Article
Myers, S. A., Al Kalifah, M. S., Lei, C., O'Neill, M., Kitney, S. P., & Kelly, S. M. (2013). The influence of the nematic phase on the phase separation of blended organic semiconductors for photovoltaics. Solar Energy Materials and Solar Cells, 116, 262-269. https://doi.org/10.1016/j.solmat.2013.05.006

Differential scanning calorimetry in combination with atomic force microscopy is used to examine the phase separation of a blended nematic liquid crystalline electron-donor and crystalline perylene electron-acceptor mixture. Separate domains of donor... Read More about The influence of the nematic phase on the phase separation of blended organic semiconductors for photovoltaics.