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A 3D cephalometric protocol for the accurate quantification of the craniofacial symmetry and facial growth (2019)
Journal Article
Pinheiro, M., Ma, X., Fagan, M. J., McIntyre, G. T., Lin, P., Sivamurthy, G., & Mossey, P. A. (2019). A 3D cephalometric protocol for the accurate quantification of the craniofacial symmetry and facial growth. Journal of Biological Engineering, 13(1), https://doi.org/10.1186/s13036-019-0171-6

© 2019 The Author(s). Background: Cephalometric analysis is used to evaluate facial growth, to study the anatomical relationships within the face. Cephalometric assessment is based on 2D radiographic images, either the sagittal or coronal planes and... Read More

Neurocranial development of the coelacanth and the evolution of the sarcopterygian head (2019)
Journal Article
Dutel, H., Galland, M., Tafforeau, P., Long, J. A., Fagan, M. J., Janvier, P., …Herbin, M. (2019). Neurocranial development of the coelacanth and the evolution of the sarcopterygian head. Nature, 569, 556–559. https://doi.org/10.1038/s41586-019-1117-3

The neurocranium of sarcopterygian fishes was originally divided into an anterior (ethmosphenoid) and posterior (otoccipital) portion by an intracranial joint, and underwent major changes in its overall geometry before fusing into a single unit in lu... Read More

Characterizing and Modeling Bone Formation during Mouse Calvarial Development (2019)
Journal Article
Marghoub, A., Libby, J., Babbs, C., Ventikos, Y., Fagan, M. J., & Moazen, M. (2019). Characterizing and Modeling Bone Formation during Mouse Calvarial Development. Physical review letters, 122(4), https://doi.org/10.1103/PhysRevLett.122.048103

© 2019 American Physical Society. The newborn mammalian cranial vault consists of five flat bones that are joined together along their edges by soft fibrous tissues called sutures. Early fusion of these sutures leads to a medical condition known as c... Read More

Modelling human skull growth: a validated computational model (2017)
Journal Article
Libby, J., Marghoub, A., Johnson, D., Khonsari, R. H., Fagan, M. J., & Moazen, M. (2017). Modelling human skull growth: a validated computational model. Journal of the Royal Society interface / the Royal Society, 14(130), 20170202. https://doi.org/10.1098/rsif.2017.0202

© 2017 The Author(s) Published by the Royal Society. All rights reserved. During the first year of life, the brain grows rapidly and the neurocranium increases to about 65% of its adult size. Our understanding of the relationship between the biomecha... Read More

Form-function relationships in dragonfly mandibles under an evolutionary perspective (2017)
Journal Article
Blanke, A., Schmitz, H., Patera, A., Dutel, H., & Fagan, M. J. (2017). Form-function relationships in dragonfly mandibles under an evolutionary perspective. Journal of the Royal Society interface / the Royal Society, 14(128), https://doi.org/10.1098/rsif.2016.1038

© 2017 The Author(s). Functional requirements may constrain phenotypic diversification or foster it. For insect mouthparts, the quantification of the relationship between shape and function in an evolutionary framework remained largely unexplored. He... Read More

The effect of boundary constraints on finite element modelling of the human pelvis (2017)
Journal Article
Watson, P., Dostanpor, A., Fagan, M. J., & Dobson, C. A. (2017). The effect of boundary constraints on finite element modelling of the human pelvis. Medical engineering & physics, 43, 48-57. https://doi.org/10.1016/j.medengphy.2017.02.001

The use of finite element analysis (FEA) to investigate the biomechanics of anatomical systems critically relies on the specification of physiologically representative boundary conditions. The biomechanics of the pelvis has been the specific focus of... Read More

Computational biomechanics changes our view on insect head evolution (2017)
Journal Article
Blanke, A., Watson, P. J., Holbrey, R., & Fagan, M. J. (2017). Computational biomechanics changes our view on insect head evolution. Proceedings. the Royal Society. Biological sciences /, 284(1848), https://doi.org/10.1098/rspb.2016.2412

© 2017 The Author(s) Published by the Royal Society. All rights reserved. Despite large-scale molecular attempts, the relationships of the basal winged insect lineages dragonflies, mayflies and neopterans, are still unresolved. Other data sources, su... Read More

A virtual approach to evaluate therapies for management of multiple myeloma induced bone disease: Modelling Therapies for Multiple Myeloma Induced Bone Disease (2015)
Journal Article
Ji, B., Genever, P. G., & Fagan, M. J. (2016). A virtual approach to evaluate therapies for management of multiple myeloma induced bone disease: Modelling Therapies for Multiple Myeloma Induced Bone Disease. International journal for numerical methods in biomedical engineering, 32(3), e02735. https://doi.org/10.1002/cnm.2735

Multiple myeloma bone disease is devastating for patients and a major cause of morbidity. The disease leads to bone destruction by inhibiting osteoblast activity while stimulating osteoclast activity. Recent advances in multiple myeloma research have... Read More

Foam pads properties and their effects on posturography in participants of different weight (2015)
Journal Article
Fagan, M., & Gosselin, G. (2015). Foam pads properties and their effects on posturography in participants of different weight. Chiropractic & manual therapies, 23(2), https://doi.org/10.1186/s12998-014-0045-4

Background: Foam pads are increasingly used on force platforms during balance assessments in order to produce increased instability thereby permitting the measurement of enhanced posturographic parameters. A variety of foam pads providing different m... Read More

Effects of cervical muscle fatigue on the perception of the subjective vertical and horizontal (2014)
Journal Article
Gosselin, G., & Fagan, M. J. (2014). Effects of cervical muscle fatigue on the perception of the subjective vertical and horizontal. SpringerPlus, 3(1), https://doi.org/10.1186/2193-1801-3-78

Introduction: Cervical functional capacity outcome measures that are simple and reliable are urgently needed in order permit accurate assessment/reassessment during treatments and rehabilitation. Induced neck muscle fatigue has been shown to alter fu... Read More

Development and three-dimensional morphology of the zygomaticotemporal suture in primate skulls (2014)
Journal Article
Curtis, N., Witzel, U., & Fagan, M. J. (2014). Development and three-dimensional morphology of the zygomaticotemporal suture in primate skulls. Folia primatologica, 85(2), 77-87. https://doi.org/10.1159/000357526

Cranial sutures are an essential part of the growing skull, allowing bones to increase in size during growth, with their morphology widely believed to be dictated by the forces and displacements that they experience. The zygomaticotemporal suture in... Read More

Functional evolution of the feeding system in rodents (2012)
Journal Article
Cox, P. G., Rayfield, E. J., Fagan, M. J., Herrel, A., Pataky, T. C., & Jeffery, N. (2012). Functional evolution of the feeding system in rodents. PloS one, 7(4), e36299. https://doi.org/10.1371/journal.pone.0036299

The masticatory musculature of rodents has evolved to enable both gnawing at the incisors and chewing at the molars. In particular, the masseter muscle is highly specialised, having extended anteriorly to originate from the rostrum. All living rodent... Read More

Improving the validation of finite element models with quantitative full-field strain comparisons (2012)
Journal Article
Gröning, F., Bright, J. A., Fagan, M. J., & O'Higgins, P. (2012). Improving the validation of finite element models with quantitative full-field strain comparisons. Journal of biomechanics, 45(8), 1498-1506. https://doi.org/10.1016/j.jbiomech.2012.02.009

The techniques used to validate finite element (FE) models against experimental results have changed little during the last decades, even though the traditional approach of using single point measurements from strain gauges has major limitations: the... Read More

The head and neck muscles associated with feeding in sphenodon (Reptilia: Lepidosauria: Rhynchocephalia) (2011)
Journal Article
Curtis, N., Jones, M. E., Junfen, S., O'Higgins, P., Evans, S. E., & Fagan, M. (2011). The head and neck muscles associated with feeding in sphenodon (Reptilia: Lepidosauria: Rhynchocephalia). Palaeontologia electronica, 12(2), 0 - 0. https://doi.org/10.1371/journal.pone.0029804

Feeding in Sphenodon, the tuatara of New Zealand, is of interest for several reasons. First, the modern animal is threatened by extinction, and some populations are in competition for food with Pacific rats. Second, Sphenodon demonstrates a feeding a... Read More

Finite element modelling of squirrel, guinea pig and rat skulls: using geometric morphometrics to assess sensitivity. (2011)
Journal Article
Cox, P. G., Fagan, M. J., Rayfield, E. J., & Jeffery, N. (2011). Finite element modelling of squirrel, guinea pig and rat skulls: using geometric morphometrics to assess sensitivity. Journal of anatomy, 219(6), 696-709. https://doi.org/10.1111/j.1469-7580.2011.01436.x

Rodents are defined by a uniquely specialized dentition and a highly complex arrangement of jaw-closing muscles. Finite element analysis (FEA) is an ideal technique to investigate the biomechanical implications of these specializations, but it is ess... Read More

The Mechanical Significance of the Temporal Fasciae in Macaca fascicularis: An Investigation Using Finite Element Analysis (2011)
Journal Article
Curtis, N., Witzel, U., Fitton, L., O'Higgins, P., & Fagan, M. (2011). The Mechanical Significance of the Temporal Fasciae in Macaca fascicularis: An Investigation Using Finite Element Analysis. Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 294(7), 1178-1190. https://doi.org/10.1002/ar.21415

Computational finite element analyses (FEAs) of the skull predict structural deformations under user specified loads and constraints, with results normally presented as stress and strain distributions over the skull's surface. The applied loads are g... Read More

The effects of the periodontal ligament on mandibular stiffness: a study combining finite element analysis and geometric morphometrics (2011)
Journal Article
Gröning, F., Fagan, M. J., & O'Higgins, P. (2011). The effects of the periodontal ligament on mandibular stiffness: a study combining finite element analysis and geometric morphometrics. Journal of biomechanics, 44(7), 1304-1312. https://doi.org/10.1016/j.jbiomech.2011.01.008

It is generally accepted that the periodontal ligament (PDL) plays a crucial role in transferring occlusal forces from the teeth to the alveolar bone. Studies using finite element analysis (FEA) have helped to better understand this role and show tha... Read More

Isolated word recognition of silent speech using magnetic implants and sensors (2010)
Journal Article
Gilbert, J. M., Rybchenko, S. I., Hofe, R., Ell, S. R., Fagan, M. J., Moore, R. K., & Green, P. (2010). Isolated word recognition of silent speech using magnetic implants and sensors. Medical engineering & physics, 32(10), 1189-1197. https://doi.org/10.1016/j.medengphy.2010.08.011

There are a number of situations where individuals wish to communicate verbally but are unable to use conventional means so called 'silent speech'. These include speakers in noisy and covert situations as well as patients who have lost their voice as... Read More

Feedback control from the jaw joints during biting: An investigation of the reptile Sphenodon using multibody modelling (2010)
Journal Article
Curtis, N., Jones, M. E. H., Evans, S., Evans, S. E., O'Higgins, P., & Fagan, M. J. (2010). Feedback control from the jaw joints during biting: An investigation of the reptile Sphenodon using multibody modelling. Journal of biomechanics, 43(16), 3132-3137. https://doi.org/10.1016/j.jbiomech.2010.08.001

Sphenodon, a lizard-like reptile, is the only living representative of a group that was once widespread at the time of the dinosaurs. Unique jaw mechanics incorporate crushing and shearing motions to breakdown food, but during this process excessive... Read More