Skip to main content

Research Repository

Advanced Search

All Outputs (19)

Registration of supine MR mammography with breast ultrasound for surgical planning of breast conserving surgery: a feasibility study (2015)
Journal Article
Pickles, M. D., Gibbs, P., Hubbard, A., Rahman, A., Wieczorek, J., Roychaudhury, R., …Turnbull, L. W. (2017). Registration of supine MR mammography with breast ultrasound for surgical planning of breast conserving surgery: a feasibility study. Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie, 38(4), 420-426. https://doi.org/10.1055/s-0041-108008

Purpose To report the feasibility, accuracy and initial clinical experience of the use of real-time magnetic resonance navigated ultrasound (rtMRnUS) in the surgical planning of breast-conserving surgery (BCS) via guide wire insertion. Materials and... Read More about Registration of supine MR mammography with breast ultrasound for surgical planning of breast conserving surgery: a feasibility study.

Impaired glucose tolerance or newly diagnosed diabetes mellitus diagnosed during admission adversely affects prognosis after myocardial infarction: An observational study (2015)
Journal Article
George, A., Bhatia, R. T., Buchanan, G. L., Whiteside, A., Moisey, R. S., Beer, S. F., …John, J. (2015). Impaired glucose tolerance or newly diagnosed diabetes mellitus diagnosed during admission adversely affects prognosis after myocardial infarction: An observational study. PLoS ONE, 10(11), e0142045. https://doi.org/10.1371/journal.pone.0142045

Objective To investigate the prognostic effect of newly diagnosed diabetes mellitus (NDM) and impaired glucose tolerance (IGT) post myocardial infarction (MI). Research Design and Methods Retrospective cohort study of 768 patients without preexisting... Read More about Impaired glucose tolerance or newly diagnosed diabetes mellitus diagnosed during admission adversely affects prognosis after myocardial infarction: An observational study.

A prospective observational study to assess the impact of operator seniority on outcome following arteriovenous fistula formation (2015)
Journal Article
Barnes, R., Smith, G. E., & Chetter, I. C. (2015). A prospective observational study to assess the impact of operator seniority on outcome following arteriovenous fistula formation. The journal of vascular access, 16(5), 372-376. https://doi.org/10.5301/jva.5000401

Purpose: Arteriovenous fistula (AVF) surgery affords an excellent opportunity for junior surgeons to learn key vascular techniques. However, implementation of the European Working Time Directive has reduced trainee surgeon’s working hours, leading to... Read More about A prospective observational study to assess the impact of operator seniority on outcome following arteriovenous fistula formation.

Association between omega-3 index and blood lipids in older Australians (2015)
Journal Article
Ferguson, J. J., Veysey, M., Lucock, M., Niblett, S., King, K., MacDonald-Wicks, L., & Garg, M. L. (2016). Association between omega-3 index and blood lipids in older Australians. Journal of Nutritional Biochemistry, 27, 233-240. https://doi.org/10.1016/j.jnutbio.2015.09.010

Management of hyperlipidaemia remains a cornerstone therapy for the prevention of cardiovascular disease (CVD). Dietary supplementation with n-3 polyunsaturated fatty acid (PUFA) has been shown to modulate blood lipid profiles and reduce the risk of... Read More about Association between omega-3 index and blood lipids in older Australians.

Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure (2015)
Journal Article
Damy, T., Hobkirk, J., Walters, M., Ciobanu, A., Rigby, A. S., Kallvikbacka-Bennett, A., …Cleland, J. G. F. (2015). Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure. Journal of Cardiovascular Pharmacology, 66(3), 229-238. https://doi.org/10.1097/fjc.0000000000000262

Background: Pulmonary hypertension is associated with poor outcome in patients with chronic heart failure (CHF) and may be a therapeutic target. Our aims were to develop a noninvasive model for studying pulmonary vasoreactivity in CHF and characteriz... Read More about Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure.

Defining chronic cough: A systematic review of the epidemiological literature (2015)
Journal Article
Song, W. J., Chang, Y. S., Faruqi, S., Kang, M. K., Kim, J. Y., Kang, M. G., …Morice, A. H. (2016). Defining chronic cough: A systematic review of the epidemiological literature. Allergy Asthma and Immunology Research, 8(2), 146-155. https://doi.org/10.4168/aair.2016.8.2.146

© The Korean Academy of Asthma, Allergy and Clinical Immunology. Purpose: Recent evidence suggests a global burden of chronic cough in general populations. However, the definitions vary greatly among epidemiological studies, and none have been valida... Read More about Defining chronic cough: A systematic review of the epidemiological literature.

A review of the potential local mechanisms by which exercise improves functional outcomes in intermittent claudication (2015)
Journal Article
Harwood, A., Cayton, T., Sarvanandan, R., Lane, R., & Chetter, I. (2016). A review of the potential local mechanisms by which exercise improves functional outcomes in intermittent claudication. Annals of vascular surgery, 30, 312-320. https://doi.org/10.1016/j.avsg.2015.05.043

© 2016 Elsevier Inc. All rights reserved. Background Intermittent claudication (IC) is a common condition which is associated with significant quality of life limitation. National Institute for Health and Care Excellence guidelines recommend a group-... Read More about A review of the potential local mechanisms by which exercise improves functional outcomes in intermittent claudication.

A systematic review and meta-analysis of systemic intraoperative anticoagulation during arteriovenous access formation for dialysis (2015)
Journal Article
Smith, G. E., Souroullos, P., Cayton, T., Harwood, A., Carradice, D., & Chetter, I. C. (2016). A systematic review and meta-analysis of systemic intraoperative anticoagulation during arteriovenous access formation for dialysis. The journal of vascular access, 17(1), 1-5. https://doi.org/10.5301/jva.5000484

Purpose: Surgical arteriovenous fistula (AVF) or graft (AVG) is preferred to a central venous catheter for dialysis access. Surgical access may suffer thrombosis early after placement and systemic anticoagulation during surgical access formation may... Read More about A systematic review and meta-analysis of systemic intraoperative anticoagulation during arteriovenous access formation for dialysis.

Divided maxillary artery in relation to the lateral pterygoid muscle (2015)
Journal Article
Aland, R. C., & Shaw, V. (2016). Divided maxillary artery in relation to the lateral pterygoid muscle. Anatomical Science International, 91(2), 207-210. https://doi.org/10.1007/s12565-015-0289-7

We describe an anatomical variation of the right maxillary artery. The variation loops deep, giving off a middle meningeal artery with an extremely short extracranial segment, then bifurcates into unequal branches. The smaller branch passes superfici... Read More about Divided maxillary artery in relation to the lateral pterygoid muscle.

Risk factors for emergency presentation with lung and colorectal cancers: A systematic review (2015)
Journal Article
Mitchell, E. D., Pickwell-Smith, B., & Macleod, U. (2015). Risk factors for emergency presentation with lung and colorectal cancers: A systematic review. BMJ open, 5(4), Article e006965. https://doi.org/10.1136/bmjopen-2014-006965

© 2015, BMJ. All rights reserved. Objective: To identify patient and practitioner factors that influence cancer diagnosis via emergency presentation (EP). Design: Systematic review. Data sources: MEDLINE, EMBASE, CINAHL, EBM Reviews, Science and Soci... Read More about Risk factors for emergency presentation with lung and colorectal cancers: A systematic review.

A randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins (2015)
Journal Article
Nandhra, S., El-sheikha, J., Carradice, D., Wallace, T., Souroullas, P., Samuel, N., …Chetter, I. C. (2015). A randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins. Journal of vascular surgery, 61(3), 741-746. https://doi.org/10.1016/j.jvs.2014.09.037

Background: This randomized clinical trial compared endovenous laser ablation (EVLA) and surgical ligation with attempted stripping in the treatment of small saphenous vein (SSV) insufficiency. The early results demonstrated that EVLA was more likely... Read More about A randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins.

Central and Peripheral Fatigue in Male Cyclists after 4-, 20-, and 40-km Time Trials (2015)
Journal Article
Thomas, K., Goodall, S., Stone, M., Howatson, G., Gibson, A. S. C., & ANSLEY, L. (2015). Central and Peripheral Fatigue in Male Cyclists after 4-, 20-, and 40-km Time Trials. Medicine and Science in Sports and Exercise, 47(3), 537-546. https://doi.org/10.1249/mss.0000000000000448

Purpose Few studies have assessed neuromuscular fatigue after self-paced locomotor exercise; moreover, none have assessed the degree of supraspinal fatigue. This study assessed central and peripheral fatigue after self-paced exercise of different d... Read More about Central and Peripheral Fatigue in Male Cyclists after 4-, 20-, and 40-km Time Trials.

Chronic kidney disease in Nigeria: an evaluation of the spatial accessibility to healthcare for diagnosed cases in Edo State (2015)
Journal Article
Oviasu, O., Rigby, J. E., & Ballas, D. (2015). Chronic kidney disease in Nigeria: an evaluation of the spatial accessibility to healthcare for diagnosed cases in Edo State. Journal of Public Health in Africa, 6(1), 40-44. https://doi.org/10.4081/jphia.2015.394

Chronic kidney disease (CKD) is a growing problem in Nigeria, presenting challenges to the nation’s health and economy. This study evaluates the accessibility to healthcare in Edo State of CKD patients diagnosed between 2006 and 2009. Using cost anal... Read More about Chronic kidney disease in Nigeria: an evaluation of the spatial accessibility to healthcare for diagnosed cases in Edo State.

Myocardial fibrosis in stroke survivors (2015)
Journal Article
Wong, K., Sze, S., Wong, S., McSwiggan, S., Allgar, V., MacWalter, R., & Struthers, A. D. (2015). Myocardial fibrosis in stroke survivors. International journal of cardiology, 187(1), 138-140. https://doi.org/10.1016/j.ijcard.2015.03.212

Stroke survivors are most likely to die of cardiac death, yet few undergo comprehensive cardiac assessment to look for reversible causes. Myocardial fibrosis (MF) is not only the hallmark of cardiomyopathy, but also a substrate for sudden cardiac dea... Read More about Myocardial fibrosis in stroke survivors.

Aspartame sensitivity? : a double blind randomised crossover study (2015)
Journal Article
Sathyapalan, T., Thatcher, N. J., Hammersley, R., Rigby, A. S., Pechlivanis, A., Gooderham, N. J., …Courts, F. (2015). Aspartame sensitivity? : a double blind randomised crossover study. PLoS ONE, 10(3), e0116212. https://doi.org/10.1371/journal.pone.0116212

Background Aspartame is a commonly used intense artificial sweetener, being approximately 200 times sweeter than sucrose. There have been concerns over aspartame since approval in the 1980s including a large anecdotal database reporting severe sympto... Read More about Aspartame sensitivity? : a double blind randomised crossover study.

Oxidized LDL activates blood platelets through CD36/NOX2–mediated inhibition of the cGMP/protein kinase G signaling cascade (2015)
Journal Article
Magwenzi, S., Woodward, C., Wraith, K. S., Aburima, A., Raslan, Z., Jones, H., …Naseem, K. M. (2015). Oxidized LDL activates blood platelets through CD36/NOX2–mediated inhibition of the cGMP/protein kinase G signaling cascade. Blood, 125(17), 2693-2703. https://doi.org/10.1182/blood-2014-05-574491

Oxidized low-density lipoprotein (oxLDL) promotes unregulated platelet activation in dyslipidemic disorders. Although oxLDL stimulates activatory signaling, it is unclear how these events drive accelerated thrombosis. Here, we describe a mechanism fo... Read More about Oxidized LDL activates blood platelets through CD36/NOX2–mediated inhibition of the cGMP/protein kinase G signaling cascade.

QT peak prolongation predicts cardiac death following stroke (2015)
Journal Article
Wong, K. Y. K., MacWalter, R. S., Wong, S. Y. S., Suich, J., Douglas, D., Fraser, H. W., …Struthers, A. D. (2015). QT peak prolongation predicts cardiac death following stroke. Journal of cardiology and current research, 2(1), Article 00050. https://doi.org/10.15406/jccr.2015.02.00050

Cardiac death has been linked in many populations to prolongation of the QT interval (QTe). However, basic science research suggested that the best estimate of the time point when repolarisation begins is near the T-wave peak. We found QT peak (QTp)... Read More about QT peak prolongation predicts cardiac death following stroke.

Prescribing patterns to optimize heart rate (2015)
Journal Article
Dierckx, R., Cleland, J. G., Parsons, S., Putzu, P., Pellicori, P., Dicken, B., …Clark, A. L. (2015). Prescribing patterns to optimize heart rate. JACC: Heart Failure, 3(3), 224-230. https://doi.org/10.1016/j.jchf.2014.11.003

Objectives This study sought to characterize patients attending a community heart failure (HF) clinic and identified those who were eligible for optimization of beta-blockers (BB) or ivabradine. Background Among patients with HF due to left vent... Read More about Prescribing patterns to optimize heart rate.

Methylation diet and methyl group genetics in risk for adenomatous polyp occurrence (2015)
Journal Article
Lucock, M., Yates, Z., Martin, C., Choi, J., Beckett, E., Boyd, L., …Veysey, M. (2015). Methylation diet and methyl group genetics in risk for adenomatous polyp occurrence. Bba Clinical, 3, 107-112. https://doi.org/10.1016/j.bbacli.2014.11.005

Purpose The aim of this study is to explore whether a methylation diet influences risk for adenomatous polyps (AP) either independently, or interactively with one-carbon metabolism-dependent gene variants, and whether such a diet modifies blood homoc... Read More about Methylation diet and methyl group genetics in risk for adenomatous polyp occurrence.